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Smoking has recently been recognised as causally associated with the development of gastric cancer (GC). However, evidence on the effect by sex, duration and intensity of smoking, anatomic subsite and cessation of smoking is limited. Our objective was to assess the relation between tobacco use and GC incidence in the European Prospective Investigation into Cancer and Nutrition (EPIC). We studied d
It is recommended that the hip joints be flexed to 90 degrees during dual-energy X-ray absorptiometry scanning of the lumbar spine in the anteroposterior projection; however, some patients are unable to maintain this position because of the presence of degenerative changes in lower limb joints. This study examines the effect of a lesser degree of hip flexion on the lumbar spine bone mineral densit
A case study is presented that evaluates the impact of partial automation strategies on productivity and ergonomics. A company partly automated its assembly and transportation functions while moving from a parallel-batch to a serial line-based production system. Data obtained from company records and key informants were combined with detailed video analysis, biomechanical modelling data and field
Two different dowel-type joints of differing size were loaded in tension parallel to the grain. The strain distribution in the joint area was studied using a contact-free measurement system. The results were compared with those of numerical analysis. The measurement system was found to be a valuable complement to traditional measurement techniques and also to numerical analyses performed in parame
Plumage ornamentation often signals the quality of males and, therefore, female birds may choose elaborately ornamented mates to increase their fitness. Such mate choice may confer both direct and indirect benefits to the offspring. Males with elaborate ornaments may provide good genes, which can result in better nestling growth, survival or resistance against parasitic infections. However, these
In the female turnip moth, Agrotis segetum, a pheromone biosynthesis activating neuropeptide (PBAN) stimulates sex pheromone biosynthesis which exhibits a daily rhythm. Here we show data supporting a circadian rhythm in PBAN release from the corpora cardiaca, which we propose regulates the endogenous rhythm in sex pheromone biosynthesis. This conclusion is drawn as the observed daily rhythm in PBA
This paper deals with a diverse fauna of polychaetes possessing jaws (= scolecodonts) from the late Silurian Kopanina Formation of the Prague Basin (Czech Republic). The most common genera are Kettnerites, Oenonites and Pistoprion; the entire collection contains at least 16 genera. This is in stark contrast to the four genera recorded from this region by previous authors. The fauna described shows
Selenium is an essential element, but its metabolism in humans is not well characterized. A few small studies indicate that the trimethylselenonium ion (TMSe) is a common selenium metabolite in humans.
Lymphomas belong to the few cancer sites with increasing incidence over past decades, and only a few risk factors have been established. We explored the association between education and the incidence of lymphoma in the prospective EPIC study. Within 3,567,410 person-years of follow-up, 1,319 lymphoma cases [1,253 non-Hodgkin lymphomas (NHL) and 66 Hodgkin lymphomas (HL)] were identified. Cox prop
Despite the widely held belief that Parkinson's disease is caused by both underlying genetics and exposure to environmental risk factors, it is still widely modelled in preclinical models using a single genetic or neurotoxic insult. This single-insult approach has resulted in a variety of models that are limited with respect to their aetiological, construct, face and/or predictive validity. Thus,
In recent years there have been increasing evidence associating liver disease with hypercoagulability, rather than bleeding. The aim of the study was to evaluate the haemostatic potential in patients with liver disease.
To determine whether expression patterns of segmentation genes found in Drosophila melanogaster can be scaled to pattern larger insects, we studied the expression of the Krüppel (Kr) gene in the blowfly Lucilia sericata. Compared with Drosophila Kr, L. sericata Kr showed an unexpected 10% shift of expression towards the anterior pole. Furthermore, expression domains not found in D. melanogaster we
One particular approach of behavioral economics has gained attention within environmental politics during the last decade. The idea of nudging (“gently pushing”) people in situations of decision-making towards the choice that in the long run is best for them as well as for the society and/or the environment seems to attract policy makers around the world. Many governments inside and outside the EU
The CJEU recently enriched its case law concerning the concept of a single taxable person through its ruling in Skandia America. Established case law differentiate two concepts of single taxable person. According to FCE Bank, a head office and its branch are to be deemed as one single taxable person, with the result that no taxable supplies occur between these entities. In Ampliscientifica, the CJ
The role of the CIO has undergone a complex transformation over the past three decades, evolving from a function which purely consisted of technical support and administration towards a high-level position of senior executive responsibility and business management. A considerable body of research exists on the role of the CIO as well as desired leadership capabilities and the CIO relationship with
On July 8, 2013, the United States and the European Union started negotiations for the Transatlantic Trade and Investment Partnership (TTIP). The TTIP is a proposed international trade and investment agreement (IIA) that aims to create the largest free trade area in the world. Despite the promises of the TTIP, including job opportunities and economic gains of over €100 billion in the EU alone, the
