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The IgG-degrading enzyme of Streptococcus pyogenes causes rapid clearance of anti-glomerular basement membrane antibodies in patients with refractory anti-glomerular basement membrane disease

In anti-glomerular basement membrane (anti-GBM) disease, IgG class autoantibodies induce rapidly progressive glomerulonephritis. Regrettably, many patients are diagnosed at a late stage when even intensive conventional treatment fails to restore renal function The endopeptidase IdeS (Immunoglobulin G degrading enzyme of Streptococcus pyogenes) (imliflidase) rapidly cleaves all human IgG subclasses

Polygenic pathways shape white matter vulnerability to Alzheimer’s disease-related pathophysiological changes

Background: The accumulation of amyloid-β1−42 (Aβ1−42) peptides and phosphorylated-Tau181 (p-Tau181) tangles from the preclinical stages of Alzheimer’s disease (AD) has led to a biological definition of the disease. However, among Aβ1−42-positive individuals, cognitive decline onset varies, and some never develop symptoms. Genetic influences on molecular pathways and their interactions with protei

Contextual adaptation, implementation, and outcomes of individual placement and support: a case study

Background: Implementing the evidence-based Individual Placement and Support (IPS) model in welfare states like Sweden faces contextual challenges that often necessitate local adaptations to enhance fit and effectiveness. While fidelity assessments aim to ensure effective outcomes, adaptations may lead to unintended drift from core components. The Model for Adaptation Design and Impact (MADI) helpBackground: Implementing the evidence-based Individual Placement and Support (IPS) model in welfare states like Sweden faces contextual challenges that often necessitate local adaptations to enhance fit and effectiveness. While fidelity assessments aim to ensure effective outcomes, adaptations may lead to unintended drift from core components. The Model for Adaptation Design and Impact (MADI) help

Ethanol from Sugarcane Lignocellulosic Residues - Opportunities for Process Improvement and Production Cost Reduction

Popular Abstract in English Modern society is still largely based on fossil resources. However, there are growing concerns about the security and cost of these resources, as well as climate change resulting from the combustion of fossil fuels. Biofuels represent renewable fuels with the potential to mitigate the adverse effects of fossil fuels, providing a more sustainable alternative. The transpBioethanol from sugarcane is a sustainable alternative to fossil fuels, and the increasing demand for fuel ethanol has prompted studies on the use of the lignocellulosic residues of sugarcane, namely bagasse and leaves, as new feedstock. This thesis describes various process designs and the economic feasibility of producing second generation (2G) ethanol from bagasse and leaves via the enzymatic r

Using Blockchain Technology and Smart Contracts to Create a Distributed Securities Depository

In the existing securities market structure, a securities trade between two parties requires the involvement of several financial intermediaries ensuring the safety of the transaction. However, the complexity of today’s market structure in conjunction with the lack of interoperability between financial data infrastructures and the disalignment of business practices, are causing costs, risks and fr

Alla är överens, men ingen tar ansvar? En kvalitativ undersökning om ansvar gällande långsiktiga boenden för barnfamiljer i hemlöshet

This study investigates how representatives from the Swedish Social Service and the Sweden City missions describe their responsibility concerning long-term housing for families in structural homelessness. The aim is also to have the representatives’ perspectives on how the situation for the target group can be improved. Even though the research concerning structural homelessness is well examined,

Skådepenningar i enväldets tjänst: Ekonomisk och politisk legitimitet i Gustav III:s kungliga medaljer 1772–1792

This bachelor’s thesis in Historical Archaeology concerns how the royal medals of the Swedish King Gustav III (1756-1792) functioned as a means of political propaganda, namely in what ways an official legitimizing narrative was created about the country’s economy and the role of the King herein, through the images and texts of the royal medals. Inspired by Clifford Geertz’ anthropological perspec

Eligibility Form LUSEM LTH N 2025

Microsoft Word - Eligibility form - new version Eligibility form This eligibility form is compulsory to fill out for any exchange student who wishes to apply for courses with prerequisites at the Lund University School of Economics and Management (LUSEM) and the Faculty of Science, or courses in Engineering at the Faculty of Engineering (LTH). Required information: Name: __________________________

https://www.science.lu.se/sites/science.lu.se/files/2025-03/Eligibility_Form_LUSEM_LTH_N_2025.pdf - 2026-04-29

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Master’s Dissertation Structural Mechanics INFLUENCE OF ANNUAL RING ORIENTATION ON COMPRESSION STRENGTH PERPENDICULAR TO GRAIN IN GLULAM Report TV SM -5203 PH ILIP W A LLIN IN FLU EN C E O F A N N U A L R IN G O R IEN TA TIO N O N C O M PR ESSIO N STR EN G TH PER PEN D IC U LA R TO G R A IN IN G LU LA M PHILIP WALLIN 5203HO.indd 15203HO.indd 1 2015-06-23 15:03:362015-06-23 15:03:36 DEPARTMENT OF C

https://www.byggmek.lth.se/fileadmin/byggnadsmekanik/publications/tvsm5000/web5203.pdf - 2026-04-27

Lab-scale versus industrial-scale thermal runaway tests for lithium-ion battery cells

Lithium-ion battery safety is a topic of large importance, and testing is associated with large costs. Safety evaluation is therefore needed also at an early stage in cell design and development, in order to evaluate potential short-comings or to screen large platforms of materials and cells. Previous thermal runaway tests on lab-scale cells have, however, indicated differences in heat release and