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High Affinity Antibodies to Plasmodium falciparum Merozoite Antigens Are Associated with Protection from Malaria

Background: Malaria kills almost 1 million people every year, but the mechanisms behind protective immunity against the disease are still largely unknown. Methodology/Principal Findings: In this study, surface plasmon resonance technology was used to evaluate the affinity (measured as kd) of naturally acquired antibodies to the Plasmodium falciparum antigens MSP2 and AMA1. Antibodies in serum samp

Proteolysis of purified IgGs by human and bacterial enzymes in vitro and the detection of specific proteolytic fragments of endogenous IgG in rheumatoid synovial fluid

A comparative in vitro survey of physiologically relevant human and microbial proteinases defined a number of enzymes that induced specific hinge domain cleavage in human IgG1. Several of these proteinases have been associated with tumor growth, inflammation, and infection. A majority of the identified proteinases converted IgG to F(ab')(2), and a consistent feature of their action was a transient

A Heterobimetallic FeIIIMnII Complex of an Unsymmetrical Dinucleating Ligand: A Structural and Functional Model Complex for the Active Site of Purple Acid Phosphatase of Sweet Potato

The heterodinuclear mixed-valence complex [FeMn(ICIMP)(OAc)(2)Cl] (1) {H2ICIMP = 2-(N-carboxylmethyl)-[N-(N-methylimidazolyl-2-methyl)aminomethyl]-[6-(N-isopropylmethyl)-[N-(N-methylimidazolyl-2-methyl)]aminomethyl-4-methylphenol], an unsymmetrical N4O2 donor ligand} has been synthesized and fully characterized by several spectroscopic techniques as well as by X-ray crystallography. The crystal st

Intercomparison of C-14 Analysis of Carbonaceous Aerosols: Exercise 2009

Radiocarbon analysis of the carbonaceous aerosol allows an apportionment of fossil and non-fossil sources of airborne particulate matter (PM). A chemical separation of total carbon (TC) into its subfractions organic carbon (OC) and elemental carbon (EC) refines this powerful technique, as OC and EC originate from different sources and undergo different processes in the atmosphere. Although C-14 an

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro

Certain monoclonal antibodies (mAbs) to type II collagen (CII) induce arthritis in vivo after passive transfer and have adverse effects on chondrocyte cultures and inhibit self assembly of collagen fibrils in vitro. We have examined whether such mAbs have detrimental effects on pre-existing cartilage. Bovine cartilage explants were cultured over 21 days in the presence of two arthritogenic mAbs to

Highly efficient CO2 and propylene oxide co-polymerization using Zn glutarate/Zn-Cr double metal cyanide composite catalyst

A highly active zinc glutarate-double metal cyanide (DMC) composite catalyst (ZnGA/Zn-CrDMC) was designed for the carbon dioxide (CO2) and propylene oxide (PO) copolymerization reaction. The composite catalyst was synthesized in a rheological phase reaction and characterized using Fourier transform infrared spectroscopy (FT-IR), powder X-ray diffraction (PXRD), and scanning electron microscopy (SE

Dissecting the properties of circulating IgG against streptococcal pathogens through a combined systems antigenomics-serology workflow

This study showcases an integrative mass spectrometry-based strategy combining systems antigenomics and systems serology to characterize human antibodies in clinical samples. This strategy involves using antibodies circulating in plasma to affinity-enrich antigenic proteins in biochemically fractionated pools of bacterial proteins, followed by their identification and quantification using mass spe

Asymptotic Performance Analysis of Distributed Non-Bayesian Quickest Change Detection with Energy Harvesting Sensors

This paper focuses on the distributed non-Bayesian quickest change detection based on the Cumulative Sum (CUSUM) algorithm in an energy harvesting wireless sensor network (WSN), where the distributions before and after the change point are assumed to be known. Each sensor is powered by randomly available harvested energy from the surroundings. It samples the observation signal and computes the log

Automatic Landing without GPS

Sagem Défense et Sécurité (now Safran Electronics & Defense), a French space and defense company of the SAFRAN group, is working on the next generation of Unmanned Aerial System (UAS). This UAS features a fully automatic Unmanned Aerial Vehicle (UAV) equipped with a state-of-the-art navigation system. This navigation system relies mainly on a high-accuracy Inertial Measurement Unit (IMU) coupl

Changing the game - The effects of a radical logo rebranding strategy on the consumer-brand relationship in football

Purpose: The purpose of this thesis is to provide an understanding of how consumer-brand relationships are affected by a radical rebranding strategy of a football club’s logo. This further leads the paper to contribute to the literature of consumer-brand relationships in the special context of football. Methodology: The interpretative nature of this research calls for a qualitative research appro

Geol01-installation av endnote

Microsoft Word - GEOL01Installation av EndNote-2.docx Installation av EndNote För att ladda ner EndNote, gå till Studentportalen (via Lunds universitets hemsida, välj Student, sedan Studentportalen, eller http://www.student.lu.se/uPortal/render.userLayoutRootNode.uP) Logga in med ditt Stil-id. Välj Mina tjänster, sedan Hämta programvaror. Gör du detta när du befinner dig utanför Lunds universitets

https://www.geology.lu.se/sites/geology.lu.se/files/geol01-installation_av_endnote.pdf - 2026-04-30

The feasibility of using Pareto fronts for comparison of treatment planning systems and delivery techniques

Pareto optimality is a concept that formalises the trade-off between a given set of mutually contradicting objectives. A solution is said to be Pareto optimal when it is not possible to improve one objective without deteriorating at least one of the other. A set of Pareto optimal solutions constitute the Pareto front. The Pareto concept applies well to the inverse planning process, which involves

Två sidor av samma mynt? - Om den dubbla tillämpningen av armlängdsprincipen under artikel 7 och 9 i OECD:s modellavtal och vilka skillnader som finns däremellan.

Armlängdsprincipen kan betraktas som en av de mest centrala principerna inom den internationella beskattningsrätten. I OECD:s modellavtal, som ligger till grund för utformningen av bilaterala dubbelbeskattningsavtal, stadgas armlängdsprincipen i artikel 9, den regel som tillåter korrigering av ett företags vinst när interna transaktioner prissatts på ett sätt som inte är armlängdsmässigt. SamtidigThe ALP can be considered one of the most significant principles within international taxation law. It is regulated under article 9 of the OECD MTC, which acts as a model for developing new bilateral tax treaties. According to article 9, the profit of an enterprise may be adjusted if the enterprise has been involved in transactions with an associated enterprise on conditions that are not of an arm

Rött kort för sportswashing: En kvalitativ analys av Saudiarabiens nationsvarumärkning

Denna kandidatuppsats är en kvalitativ undersökning över hur länder i en rykteskris använder nationsvarumärkning och mjuk makt för att motverka negativa stereoty- per och förbättra sitt globala rykte. Nationsvarumärkning beskrivs som ett strate- giskt verktyg för att förbättra ett lands rykte och attraktivitet genom olika mark- nadsförings- och varumärkesmetoder. Flerstegsmodellen introduceras som

Khm2 info samlad sv feb 19

Konsthögskolans galleri, KHM2, Bergsgatan 29, 3 våning Kontakta Sophie eller respektive tekniker om utrustning du vill låna. Kontakta Kristian i god tid för att planera transporten till lokalen. Samtransport från Khm till Galleriet och lastning av föregående utställningar för tillbakatransport till Khm, på måndag f.m. För att få tillträde till byggnaden, hissen och gallerirummet måste du ha ett LU

https://www.khm.lu.se/en/sites/khm.lu.se.en/files/khm2_info_samlad_sv_feb_19.pdf - 2026-04-30