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BACKGROUND: Accumulating evidence suggests a relationship between endometrial cancer and ovarian cancer. Independent genome-wide association studies (GWAS) for endometrial cancer and ovarian cancer have identified 16 and 27 risk regions, respectively, four of which overlap between the two cancers. We aimed to identify joint endometrial and ovarian cancer risk loci by performing a meta-analysis of
BACKGROUND: The objective of this study was firstly to develop and evaluate an automated method for the detection of new lesions and changes in bone scan index (BSI) in serial bone scans and secondly to evaluate the prognostic value of the method in a group of patients receiving chemotherapy.METHODS: The automated method for detection of new lesions was evaluated in a group of 266 patients using t
The arsenic adsorption characteristics of a macroporous polymer coated with coprecipi-tated iron-aluminium hydroxides (MHCMP) is evaluated in this study. The MHCMP had a maximum adsorption capacity of 82.3 and 49.6 mg As/g adsorbent for As(III) and As(V) ions respectively. Extended X-ray Absorption Fine Structure (EXAFS) confirmed that binding of As(III) ions took place on the iron hydroxides coat
The production of D*±, D± and Ds ± charmed mesons has been measured with the ATLAS detector in pp collisions at s=7 TeV at the LHC, using data corresponding to an integrated luminosity of 280 nb-1. The charmed mesons have been reconstructed in the range of transverse momentum 3.5
Background: Arterial hypertension is common in adults with repaired coarctation of the aorta, and is associated with several severe complications. Aims: This study aimed to investigate the prevalence of poorly controlled (⩾140/90 mmHg) blood pressure among patients with diagnosed hypertension and to identify associated factors. Methods: In the national register for CHD, adults with repaired coarct
BACKGROUND: Lower urinary tract symptoms (LUTS) have a significant impact on quality of life (QoL) in post-stroke patients. AIM: The aim of this study was to evaluate the effect of pelvic floor muscle training (PFMT) on QoL parameters in men with post-stroke LUTS. DESIGN: Randomized, controlled and single-blinded trial. SETTING: Outpatients, University Hospital. POPULATION: Thirty-one men, median
The diagnostic steps for primary aldosteronism (PA) include case screening tests, confirmatory tests, and localization. The aim of this study was to identify useful confirmatory tests and their cut-off values for differentiating the subtype of primary aldosteronism, especially in unilateral PA, such as aldosterone-producing adenoma, and bilateral PA, such as idiopathic hyperaldosteronism. Seventy-
In this chapter, we explore whether eyeblinks can be used as a measurementof spectators’ narrative transportation into a cinematic narrative. In ourexperiment, we show that spectators’ eyeblinks increase when watchingfilm clips together with what might be called congruent music. Increasedeyeblinks indicate an emotional arousal that motivates attention, whichin turn is a prerequisite for narrative
An ultrasonically-enhanced mechanochemical method was developed to synthesize CaFe-layered double hydroxides (LDHs) with various interlayer anions (CO3 2−, NO3 −, ClO4 −, N3 −, F−, Cl−, Br− and I−). The duration of pre-milling and ultrasonic irradiation and the variation of synthesis temperature in the wet chemical step were investigated to obtain the optimal parameters of preparation. The main me
Background: Chronic rhinosinusitis with and without nasal polyps (CRSw/sNP) are common conditions decreasing health-related quality of life (HRQOL). Individual symptoms capable of predicting outcome after endoscopic sinus surgery (ESS) are poorly defined, and the indirect costs of CRS is rarely reported in Europe. Methodology: Patients with CRSw/sNP admitted for ESS were prospectively enrolled. Pa
This report describes the characterization of Swedish families with inherited resistance to activated protein C (APC resistance) and/or protein S deficiency, two genetic disorders associated with functional impairment of the protein C anticoagulant pathway. The APC resistance phenotype was linked to the factor V gene locus in a kindred with independent inheritance of APC resistance and protein S d
Background It has been reported increased serum apoM levels seen in the patients suffered from obstructive sleep apnoea and chronic obstructive pulmonary diseases. In the present, we further examine the prevalence of apoM gene SNPs in COPD patients. And a new method base-quenched probe technique is established. Methods In the present study, we first used the Roche 454 GS Junior high-throughput seq
Background: Combinations of multiple fatty acids may influence cardiometabolic risk more than single fatty acids. The association of a combination of fatty acids with incident type 2 diabetes (T2D) has not been evaluated. Methods and findings: We measured plasma phospholipid fatty acids by gas chromatography in 27,296 adults, including 12,132 incident cases of T2D, over the follow-up period betwee
During recent years, numerous studies have shown the ability of dietary fiber toprotect the colon from disease and to improve intestinal health. Beneficial healtheffects, such as the lowering of blood cholesterol levels and a reduction in the risk of coronary heart disease, are often directly related to cereal β-glucan, one of the major components of dietary fiber found in oat and barley. No defin
Purpose: A multifunctional diet (MFD) targeting subclinical inflammation was developed as a tool to decrease risk factors for cardiometabolic disease in healthy “at-risk” individuals (BMI 25–33 kg/m2). MFD contains several components that are degraded in the colon by the microbiota, such as dietary fibers from rye, barley, oats and berries. It also contains soy beans, oily fish and plant stanols.
BACKGROUND: Symptoms of anxiety, irritability, and agitation (AIA) are prevalent among patients with bipolar I disorder (BD-I) mania with depressive symptoms, and could potentially be used to aid physicians in the identification of this more severe form of BD-I. Using data from two clinical trials, the aims of this post hoc analysis were to describe the phenomenology of bipolar mania in terms of A
Carbon fiber reinforced plastics, CFRP, are attractive materials not only because of their strength and stiffness but also because of their electrical conductivity and high thermal conductivity and diffusivity. One application where induction heating of CFRP is particularly interesting is tools for fast thermal cycling, beneficial inmany industrial processes, for example in composite manufacturingCarbon fiber reinforced plastics, CFRP, are attractive materials not only because of their strength and stiffness but also because of their electrical conductivity and high thermal conductivity and diffusivity. One application where induction heating of CFRP is particularly interesting is tools for fast thermal cycling, beneficial in many industrial processes, for example in composite manufacturin
