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Cold adapted yeasts as producers of cold active polygalacturonases
Eight cold-adapted, polygalacturonase-producing yeasts belonging to four species were isolated from frozen environmental samples in Iceland. They were identified as Cystofilobasidium lari-marini, Cystofilobasidium capitatum, Cryptococcus macerans and Cryptococcus aquaticus species by sequence analysis of rDNA regions. Growth behavior of the isolates was investigated. All strains could grow at 2°C.
Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast
Individual patient data were available for all four of the randomized trials that began before 1995, and that compared adjuvant radiotherapy vs no radiotherapy following breast-conserving surgery for ductal carcinoma in situ (DCIS). A total of 3729 women were eligible for analysis. Radiotherapy reduced the absolute 10-year risk of any ipsilateral breast event (ie, either recurrent DCIS or invasive
The most valuable areas for preservation of biodiversity in southern Sweden – woodliving beetles as guides to hot-spots
In Sweden a new red list was issued 2000, but there is no published list of the most important areas for biodiversity preservation. I use woodliving and red-listed beetles as indicators of “hot-spots” for biodiversity preservation, since these insects constitute a large proportion of the red-listed forest living species in Sweden. Based on museum and many large private collections of beetles from
Signal-averaged P wave analysis for delineation of interatrial conduction - Further validation of the method
ABSTRACT: BACKGROUND: The study was designed to investigate the effect of different measuring methodologies on the estimation of P wave duration. The recording length required to ensure reproducibility in unfiltered, signal-averaged P wave analysis was also investigated. An algorithm for automated classification was designed and its reproducibility of manual P wave morphology classification invest
Patterns of Care : Relating Altruism in Sociobiology and the Christian Tradition of Agape
Popular Abstract in Swedish Avhandlingens titel Patterns of Care: Relating Altruism in Sociobiology and the Christian Tradition of Agape kan översättas som Omsorgsmönster: Förhållandet mellan hur altruism förstås i sociobiologin och den kristna agape-traditionen. (Ordet agape är grekiska för kärlek. Sociobiologi är ett naturvetenskapligt forskningsprogram som undersöker socialt beteendes biologisThe purpose of this study is to relate sociobiological theories of altruism to theories within the Christian tradition of agape. Firstly, it discusses the relation between scientific, ethical and theological understandings of altruism, and argues that it is possible to compare discussions of benevolent acts towards others or other-directedness. Such acts are determined in content by the extent an
Bioinformatic analysis of protein structure-function relationships: case study of leukocyte elastase (ELA2) missense mutations.
Cyclic and congenital neutropenia are caused by mutations in the human neutrophil elastase (HNE) gene (ELA2), leading to an immunodeficiency characterized by decreased or oscillating levels of neutrophils in the blood. The HNE mutations presumably cause loss of enzyme activity, consequently leading to compromised immune system function. To understand the structural basis for the disease, we implem
Text Production in Adults with Reading and Writing Difficulties
This thesis deals primarily with the production of written texts by adults with reading and writing difficulties. Their writing is analysed from three different aspects: error analysis, non-error-oriented text analysis and analysis of the production process. These studies are based on data from on-line recordings of writing. The main question is how the written language production of adults with r
Autologous cranioplasty following decompressive craniectomy in the trauma setting
Background. Decompressive craniectomy (DC) is an option for the treatment of increased intracranial pressure resulting from an acute neurological insult, including insults caused by trauma. When the brain swelling has receded, the skull is reconstructed with a wide choice of materials, each with its own advantages and disadvantages in terms of cost, cosmetic appearance, biocompatibility, implant s
Inter-market variability in CO2 emission-intensities in tourism: Implications for destination marketing and carbon management
There is a growing gap between tourism's rapidly growing greenhouse gas emissions and the sector's 'aspirational' emission reduction targets as well as the international policy consensus to reduce emissions from this and all other sectors of the economy. The transport component is the largest GHG contributor to the global tourism system. In the absence of supranational policy agreements to curb em
Sex differences in muscular load among house painters performing identical work tasks
The present study aimed to estimate possible differences in upper body muscular load between male and female house painters performing identical work tasks. Sex-related differences in muscular load may help explain why women, in general, have more musculoskeletal complaints than men. In a laboratory setting, 16 male and 16 female house painters performed nine standardised work tasks common to hous
Phase-difference and spectroscopic imaging for monitoring of human brain temperature during cooling
Decrease of the human brain temperature was induced by intranasal cooling. The main purpose of this study was to compare the two magnetic resonance methods for monitoring brain temperature changes during cooling: phase-difference and magnetic resonance spectroscopic imaging (MRSI) with high spatial resolution. Ten healthy volunteers were measured. Selective brain cooling was performed through nasa
Gender-specific differences in carotid intima-media thickness and its progression over three years: A multicenter European study
Background and aims: This multicentre European study evaluated, in a young-to-middle-aged healthy population without carotid atherosclerosis, the gender-related differences in carotid intima-media thickness (IMT) and its short-term (3-year) progression, and whether these differences are related to different vascular ageing rate, cardiovascular risk profile or different susceptibility to family pre
18F-AV-1451 and CSF T-tau and P-tau as biomarkers in Alzheimer's disease
To elucidate the relationship between cerebrospinal fluid (CSF) total-tau (T-tau) and phosphorylated tau (P-tau) with the tau PET ligand 18F-AV-1451 in Alzheimer's disease (AD), we examined 30 cognitively healthy elderly (15 with preclinical AD), 14 prodromal AD, and 39 AD dementia patients. CSF T-tau and P-tau were highly correlated (R = 0.92, P < 0.001), but they were only moderately associated
Shrunken pore syndrome and mortality : a cohort study of patients with measured GFR and known comorbidities
Shrunken pore syndrome (SPS) is defined by a cystatin C-based estimation of glomerular filtration rate (eGFRCYS) being less than 60% or 70% of a creatinine-based GFR estimation (eGFRCR) in the absence of extrarenal influences on cystatin C or creatinine concentrations. SPS has been associated with a substantial increase in mortality or morbidity in all investigated populations. However, in these s
A reduced chemical kinetic reaction mechanism for kerosene-air combustion
Development of a new reduced chemical kinetic reaction mechanism for kerosene-air combustion is presented. The new mechanism uses a modular based development technique and is a further development on previously presented kerosene-air mechanisms. The new mechanism consists of 30 species and 77 irreversible reactions and is developed to accurate reproduce key flame parameters yet being small enough
Parents in adult psychiatric care and their children : a call for more interagency collaboration with social services and child and adolescent psychiatry
Background: A parental mental illness affects all family members and should warrant a need for support. Aim: To investigate the extent to which psychiatric patients with underage children are the recipients of child-focused interventions and involved in interagency collaboration. Methods: Data were retrieved from a psychiatric services medical record database consisting of data regarding 29,972 in
Impaired brain metabolism and neurocognitive function in childhood leukemia survivors despite complete hormone supplementation in adulthood
Cranial radiotherapy is a known risk factor for neurocognitive impairment in survivors of childhood acute lymphoblastic leukemia (ALL). Understanding the nature of cognitive dysfunction during adulthood in ALL survivors is important as it has an impact on major life situations. Thirty-eight (21 women) ALL survivors were investigated 34 years after diagnosis. Median-age was 38 (27–46) years. All we
Pullout strength of all suture anchors in the repair of rotator cuff tears: a biomechanical study.
Faxeholm i maktens landskap : en historisk arkeologi
Popular Abstract in Swedish Hur gick det till när det svenska riket expanderade norrut och införlivade Hälsingland? Denna bok är uppställd som en generalhypotes över denna långt utdragna process, som tar sin utgångspunkt i den samhälleliga kollaps som är skönjbar under 500-talet. De inhemska maktstrukturer som gradvis byggdes upp efteråt kom under medeltidens inledande århundraden att få känna på
