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Preclinical Studies of Crosstalk between Pathways in Breast Cancer
Abstract Breast cancer is the most commonly diagnosed type of cancer in women worldwide. Inherited or acquired aberrations of genes in DNA damage repair, cell cycle checkpoint, apoptosis, and growth signaling pathways are responsible for the generation of breast cancer. Recently, increasing evidence shows that signaling pathways can be highly interconnected and are interacting with each other rat
KBT behandling i grupp för vuxna med ADHD
The purpose of the present study was to examine the potential effectiveness of a group cognitive-behavioral therapy (CBT) for adults with attention-deficit hyperactivity disorder (ADHD) with residual significant clinical symptoms after being stabilized on medication. All adult patients with ADHD in an outpatient psychiatric clinic who had been stabilized on medication but still showed clinical sig
Ökad hänvisning till ljud- och bildupptagning i hovrätten - Vilka är nackdelarna?
Sammanfattning Sedan den första november 2008 har metoden för framställning av muntlig bevisning i hovrätt ändrats. Med anledning av reformen ”En modernare rättegång” moderniserades rättegången i hovrätten. Moderniseringen innebar bland annat att ljud- och bildupptagning som gjorts i tingsrätten, i regel spelas upp som muntlig bevisning i hovrätten. Nu finns förslag på att den delen av hovrättsförSummary Since November 1st 2008, the method of presenting oral testimonies in the Swedish Court of Appeal has changed. Since the reform “More modern court proceedings” the trials in Court of Appeal have become modernized. The modernization meant, inter alia, that audiovisual recording that have been conducted at the Swedish District Courts are, as a rule, played at the Court of Appeal. The recordi
Constitutionalizing the International Normative Environment: An Investigation of the Systemic Nature of International and Global Law
2005 släppte Förenta Nationernas folkrättskommission rapporten "Fragmentation of International Law: Difficulties arising from the diversification and expansion of International Law". Även om fragmenteringen av folkrätten hade varit ett diskussionsämne långt före 2005 fick rapporten verkligen debatten ta fart och fragmentering att bli en av de mest omdebatterade frågorna under senare år bIn 2005 the United Nations International Law Commission released the report Fragmentation of International Law: Difficulties arising from the diversification and expansion of International Law. Although fragmentation of international law had been a topic of discussion long before 2005 the report really made the debate take off, becoming one of the most debated issues in recent years among internat
Reformeringen av Sveriges säkerhet - En studie om Sveriges krishantering av tsunamin i Thailand år 2004, och reformeringen av säkerheten som skedde därefter
In the year of 2004, a tsunami struck the coast of Thailand. Around 30 000 Swedish tourist was present, and over 500 was killed. The Swedish government acted slowly in helping its citizens, which created a political crisis in Sweden when the support for the government declined. After the crisis management of the tsunami was over, the government started to reform Sweden’s national security. The mai
Fastighetspaketering - Hur bör man sätta stopp för ett oönskat skatteplaneringsförfarande?
Istället för att ett bolag säljer en fastighet direkt kan bolaget sälja ett dotterbolag som äger fastigheten och därmed undgå beskattning på vinsten på försäljningen tack vare reglerna om näringsbetingade andelar. Förfarandet kallas fastighetspaketering. Fastighetspaketering kan genomföras med olika bolagstyper och i olika bolagsstrukturer. Vissa av paketeringsuppläggen har tidigare angripits med Instead of a company selling real estate directly, the company may sell a subsidiary that owns the the real estate and thus avoid taxation on the profit of the sale due to the rules on business-related shares. The process is called packaging of assets, in this case regarding real estate. Packaging of real estate can be carried out using different types of companies and in different corporate struc
Biology and distribution of chafers (Coleoptera, Scarabaeidae) living in hollow trees in Sweden.
We review the ecology and distributions of the chafers Liocola marmorata (F.), Gnorimus nobilis (L.) and Gnorimus variabilis (L.) in Sweden based on museum and several large private collections. These species live in hollow deciduous trees, in Sweden especially in oaks. The former and recently documented localities are shown on maps. More than 100 years ago, all the species as well as their habita
Measurement of linewidths and permanent electric dipole moment change of the Ce 4f-5d transition in Y2SiO5 for qubit readout scheme in rare-earth ion based quantum computing
In this work the inhomogeneous (zero-phonon line) and homogeneous linewidths and the permanent electric dipole moment change (averaged value of all dipole orientations) for the Ce 4f-5d transition in Y2SiO5 were measured in order to investigate the possibility for using Ce as a sensor to detect the hyperfine state of a spatially close-lying Pr or Eu ion. The experiments were carried out on Ce dope
Factors influencing PM10 emissions from road pavement wear
Accelerated pavement wear is one of the major environmental disadvantages of studded tyres in northern regions and results in increased levels of PM10. Measurements of PM10 in a road simulator hall have been used to study the influence of pavement properties, tyre type and vehicle speed on pavement wear. The test set-up included three different pavements (one granite and two quartzite with differe
Reduction behavior of oxidized Pd(100) and Pd75Ag25(100) surfaces using CO
The reduction of the (A root 5x root 5)R27 degrees surface oxide on Pd(100) and Pd75Ag25(100) surfaces by CO has been investigated by high-resolution X-ray photoelectron spectroscopy in combination with kinetic analysis using the Avrami-Erofeev theory. For both surfaces we observed faster reduction with increasing temperature. Kinetic analysis indicates that the reduction process is phase boundary
Epidemiology of MRSA in southern Sweden: strong relation to foreign country of origin, health care abroad and foreign travel
Pollen production estimates (PPEs) and fall speeds for major tree taxa and relevant source areas of pollen (RSAP) in Changbai Mountain, northeastern China
For model-based quantitative reconstructions of past vegetation cover on the scale of landscapes, pollen productivity estimates (PPEs) are key input parameters. In this study, we employed a random sampling strategy to collect moss polsters at 20 sites in Changbai Mountain, northeastern China. A detailed vegetation survey within 1000-m radius around each sampling point was carried out and digitized
High maternal body mass index increases the risk of neonatal early onset group B streptococcal disease
Objective: The aim of this study was to analyse the occurrence of neonatal early onset group B streptococcal (EOGBS) disease relative to maternal body mass index (BMI). Method: A cohort of Swedish parturients with an early pregnancy BMI registered was investigated. Data were retrieved from population-based registers during 1997-2001, (n = 344 127, elective caesarean section excluded). Medical reco
Endograft Repair of Complicated Acute Type B Aortic Dissections
Objectives: This study aims to assess patient outcomes and aortic remodelling following coverage of the proximal entry tear with an endograft in complicated acute type B aortic dissections (caTBADs). Material and methods: All patients with caTBAD treated with a thoracic endograft in three high-volume vascular centres were retrospectively studied. Inclusion criteria were branch-vessel malperfusion,
Rapid ecosystem response to abrupt climate changes during the last glacial period in western Europe, 40-16 ka
We present a high-resolution and independently dated multiproxy lake sediment record from the paleolake at Les Echets in southeastern France that displays synchronous changes in independent limnic and terrestrial ecosystem proxies, in concert with millennial-scale climate oscillations during the last glacial period. Distinct lake-level fluctuations, low lake organic productivity, and open, treeles
Structures and burning velocity of biomass derived gas flames
Biomass derived gases produced via gasification, pyrolysis, and fermentation are carbon neutral alternative fuels that can be used in gas turbines, furnaces, and piston engines. To make use of these environmentally friendly but energy density low fuels the combustion characteristics of these fuels have to be fully understood. In this study the structure and laminar burning velocity of biomass deri
Upper gastrointestinal bleeding: incidence, etiology and outcomes in a population-based setting
Objective. The authors aimed to investigate the incidence and outcomes of acute upper gastrointestinal bleeding (AUGIB) and to examine the role of drugs potentially associated with AUGIB. Methods. The study was prospective, population-based and consisted of all patients who underwent upper gastrointestinal endoscopy (UGE), during the year of 2010 at the National University Hospital of Iceland. Dru
Preliminary results of oxygen isotope ratio measurement with a particle-gamma coincidence method
The possibility to study variations in the oxygen isotopic ratio with photon tagged nuclear reaction analysis (pNRA) is evaluated in the current work. The experiment described in the article was performed at Lund Ion Beam Analysis Facility (LIBAF) with a 2 MeV deuteron beam. Isotopic fractionation of light elements such as carbon, oxygen and nitrogen is the basis of many analytical tools in hydrol
