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In current recommendations from FAO/WHO, foods that elicit low glycaemic responses and thus have low glycaemic indices (GIs) are advocated. The rationale for this recommendation is that low-GI diets have been shown to reduce risk factors for e.g. type II diabetes and cardiovascular disease. A major problem in this context is that most important starch rich staple foods in our diet, such as potato
Background: Graft rejection (GR) is common complication after haploidentical hematopoietic cell transplantation (haplo-HCT). There are only a few studies describing the clinical presentation and potential risk factors of GR, and the optimal rescue strategy is not established. Objectives: To evaluate the cumulative incidence and potential risk factors for GR following haplo-HCT, and to compare surv
Introduction: South Africa has one of the highest incidence rates of notified tuberculosis (TB) in the world. Achieving TB control requires strengthening treatment and support services. The implementation of differentiated delivery models can be used to improve service quality and enhance retention in care. This study aimed to identify treatment and support delivery preferences among people on TB
Aims: To assess the prevalence and prevalence relative risk (PRR) of Type 1 diabetes mellitus (T1DM) and Type 2 diabetes mellitus (T2DM) among people with intellectual disabilities (ID) compared to the general population using a register-based cohort in Sweden. Methods: The study included 14,716 people with ID and 1226,955 people from the general population in Skåne, Sweden, on January 1st, 2014.
Background: The aim of heart transplantation is prolonged survival and improved quality of life. Chronic pain is a common and distressing symptom after heart transplantation. To our knowledge, there are no person-centred interventions aimed at chronic pain and symptom distress after heart transplantation. The aim was to assess the feasibility and acceptability of systematic, person-centred symptom
The Late Pleistocene cataclysmic releases of glacial meltwater left distinct footprint across the Central European Lowland. Deeply incised tunnel valleys, oversized ice-marginal spillways, fields of mega-dunes, and glacial curvilineations carved by rapid drainage events occur along the southern margin of the last (Weichselian) Scandinavian Ice Sheet margin. These meltwater releases contributed sigThe Late Pleistocene cataclysmic releases of glacial meltwater left distinct footprint across the Central European Lowland. Deeply incised tunnel valleys, oversized ice-marginal spillways, fields of mega-dunes, and glacial curvilineations carved by rapid drainage events occur along the southern margin of the last (Weichselian) Scandinavian Ice Sheet margin. These meltwater releases contributed sig
Introduction. The fourth edition of the Transatlantic Orthopedic Surgery Webinar 2022 took place on December 12th, 2022. The main theme of the webinar was the treatment of crouch gait in children with cerebral palsy (CP). Speakers from Australia, Canada, China, Germany, India, Poland, Spain, Sweden, Turkey, the United Kingdom, and the United States participated. Results. The first general session
This paper reports on the challenges of handling menstrual waste in informal settlements in Kisumu, Kenya, and the emerging conflicts between reducing the use of these ‘complicated plastics’ and ensuring human health and dignity. To investigate these interconnections, we draw on a survey conducted among sanitation workers conducting manual pit emptying. We then conducted a knowledge co-production
Background: Stereotactic body radiotherapy (SBRT) is an established treatment for previously unirradiated spinal metastases; however, the literature is limited with respect to SBRT as a re-irradiation salvage therapy. We performed a systematic review and meta-analysis as basis for joint ESTRO-ISRS clinical practice recommendations of salvage SBRT for spinal metastases. Methods: A systematic review
Herein, we present a case of severe immune-related adverse events (irAEs), myocarditis with myositis, and myasthenia gravis overlap syndrome (IM3OS) in a patient receiving an immune checkpoint inhibitor (ICI), as adjuvant therapy after surgery for muscle-invasive bladder cancer. An 80-year-old woman who had undergone a total cystectomy for bladder cancer presented with ptosis, diplopia, and paraly
Background: Insulin resistance and impaired insulin secretion are hallmarks of type 2 diabetes (T2D) and may influence risks of complications including dementia. We investigated dementia risk across T2D subgroups defined by beta-cell function and insulin sensitivity. Methods: We used Homeostasis Model Assessment-2 indices of beta-cell function (HOMA2-B) and insulin sensitivity (HOMA2-S) to classif
In the future, buildings need to be energy resilient to tackle the energy crisis. This article introduces a concept for classifying the energy resilience of buildings in extreme cold and warm weather in Finland during blackouts. It presents a techno-economic comparison between an old and a new single-family building integrated with photovoltaic (PV) systems and batteries, analyzing their resilienc
IntroductionMidwifery knowledge, education and training in practice are challenged in contemporary maternity care by the growing trend towards interventions during childbirth, a dominant risk perspective and medicalised care. There is an ongoing debate about the definition of normal birth, however, midwives continue to advocate for normal birth.ObjectiveTo explore midwives’ views and definitions o
Electric power systems are undergoing significant transformations as more sectors in society are electrified and new electric power generation from solar and wind is added to the grid. The growing share of renewable generation is expected to influence the dynamic behaviour of power systems, creating a need to develop new control strategies for power systems. This thesis investigates robust and opt
A separation between mecA+ strains of Staphylococcus aureus and strains lacking mecA was achieved by the disk diffusion assay and the agar dilution method, utilizing disks containing 5 microg of oxacillin and inocula of approximately 5 x 10(5) CFU/spot, respectively, provided that agar with 0 to 0.5% NaCl and incubation at 30 degrees C were employed. The 5-microg oxacillin disks clearly discrimina
An open, crossover and randomized study was carried out to compare the safety and efficacy of salbutamol inhaled using the dry-powder inhaler Turbuhaler, and using a pressurized metered-dose inhaler (pMDI). Twelve patients with moderate to severe asthma, aged 47-68 years, were included in the study. On two separate days, patients received a total dose of 1600 micrograms of salbutamol administered
Clinicians may record patients presenting with osteoarthritis (OA) symptoms with joint pain rather than an OA diagnosis. This may have implications for OA research studies and patient care. The objective was to assess whether older adults recorded with joint pain are similar to those with a recorded OA diagnosis.
Maternal enterovirus infections during pregnancy may increase the risk of offspring developing type 1 diabetes during childhood. The aim of this study was to investigate whether gestational enterovirus infections increase the offspring's risk of type 1 diabetes later in life. Serum samples from 30 mothers without diabetes whose offspring developed type 1 diabetes between 15 and 25 years of age wer
