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Mitochondrial diseases involve the dysfunction of the oxidative phosphorylation (OXPHOS) system. This group of diseases presents with heterogeneous clinical symptoms affecting mainly organs with high energy demands. Defects in the multimeric complexes comprising the OXPHOS system have a dual genetic origin, mitochondrial or nuclear DNA. Although many nuclear DNA mutations involve genes coding for

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The legitimacy of the judiciary hinges on the presumption that truth can be found through the judicial process. Even though a distinction can be made between "truth" in a legal sense and "real truth", the legal truth can only be justified by its anchorage in "real truth". During the last few decades, the previosly all-powerful assumption of the objective nature of reality and knowledge has been ch

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In this article, a framework for hadronic rescattering in the general-purpose Pythia event generator is introduced. The starting point is the recently presented space–time picture of the hadronization process. It is now extended with a tracing of the subsequent motion of the primary hadrons, including both subsequent scattering processes among them and decays of them. The major new component is cr

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Which images are made manifest across an artist’s practice and which are the ones that disappear? How do objects—whether seen or unseen—and the knowledge they possess traverse across place and time to avow their resistance? These are amongst the questions asked by artist Nour Bishouty in her artist’s book 1—130, a project that draws upon her ongoing research into the works of her father, Ghassan B

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Background: We studied whether nitrous oxide (N(2)O) added to a fluid allows the infused volume to be quantified by measuring N(2)O in the expired air during normal breathing. If so, N(2)O might serve as a tracer of fluid absorption during endoscopic surgery.Methods: Twelve male volunteers received continuous and intermittent i.v. infusions (5-45 min) of fluid containing 40 ml litre(-1) of N(2)O.

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Background: The protein C anticoagulant system plays a key role in maintaining the hemostatic balance. Although several studies have identified thrombomodulin gene (THBD) variants among venous thromboembolism (VTE) patients, the role of THBD in relation to VTE in humans remains to be clarified. Objectives: This study aimed to determine the thrombotic risk of rare and common THBD variants in a larg

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Numerical analysis have been performed on tensile test experiment data to evaluated the performances of a 9 microns thick aluminium foil. The identification of the anisotropic material properties is based on tensile tests performed in 11 di↵erent angles from 0 to 90 from the rolling direction. By least square fitting and extrapolation to zero load the elastic modulus is, as opposed to the general Numerical analysis have been performed on tensile test experiment data toevaluated the performances of a 9 microns thick aluminium foil. The identification of theanisotropic material properties is based on tensile tests performed in 11 different anglesfrom 0◦to 90◦from the rolling direction. By least square fitting and extrapolation tozero load the elastic modulus is, as opposed to t

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We show that entrepreneurs are co-located within cities. One plausible source of such spatial clustering is local social interactions, where individuals' decisions to become entrepreneurs are influenced by entrepreneurial neighbors. Using geo-coded matched employer-employee data for Sweden, we find that sharing residential neighborhood with established entrepreneurs has a statistically significant

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Background: As part of I-O Optimise, a multinational research platform providing real-world insights into the management of lung cancers, the SCAN-LEAF study aims to describe the epidemiology, clinical care, and outcomes for pts with NSCLC in Scandinavia. Here, we report temporal OS trends among pts diagnosed with incident NSCLC from 2005 to 2015 in Denmark and Sweden. Methods: The SCAN-LEAF Danis

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In this presentation I will focus on lessons from the arts to qualitative inquiry, especially, what reflection on jazz improvisation may bring to qualitative inquiry. First, I will make the general suggestion that qualitative investigations, seen as reflective practices, have much in common with – and probably much to learn from – jazz improvisational practices. The complex processes of hermeneuti

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This thesis analyzes the legitimacy of lay judge’s participation in Swedish courts, addressed as ‘nämndemän’. The Swedish lay judges are assigned in accordance to the proportional share that the political parties receive in the municipal elections. Lay judges therefore represent a political party in court, though sworn by oath not to be affected by it in their judging. The question stated is wheth

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In recent years there has been an intensive discussion about how Sweden should be organized in the future. At the turn of 2010/2011six Halland communes formed Region Halland. In this thesis the changes of the Swedish state space are studied through a theoretical approach which focuses on the spatial selectivity. By the concept of spatial selectivity the political-economic aspects of spatial chang

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Across 2016 and 2017, YouTube was subjected to an advertising boycott, widely known as the Adpocalypse, after a number of adverts were placed in content that promoted extremism. In response YouTube undertook a complete restructuring of their advertiser-friendly guidelines. These changes involved a number of restrictions on the content creators, who were forced to adapt or risk losing out. The chan

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This thesis uses an evaluative approach to analyse the European Union’s Eel Regulation Framework (ERF). By using theories on both legitimacy and posthumanism, the aim of the study is to answer the question of in which ways the ERF can be considered legitimate with both human and non-human stakeholders in mind. As environmental issues and biodiversity loss become increasingly severe, there is an ur

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Since the collapse of the Bretton Woods system, the system of fixed exchange rates amongst principal industrial countries, in the early 1970s, a new era began, introducing the floating exchange rate regime. Since the inception of the floating rate regime, the general interest in forecasting exchange rate movements has grown considerably. Yet, forecasting the exchange rate is extremely difficult, a

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The lifetime extension of smartphones is seen as a prominent way to reduce the environmental impacts caused during the production of the devices. Smartphones may be small devices, but their impact is no longer small as for the past years e-waste has been the largest growing waste generated globally. This research aimed to learn what perspectives Swedish smartphone users had towards repairability a