Filtyp
AIMS/HYPOTHESIS: Type 1 diabetes in children is characterised by autoimmune destruction of pancreatic beta cells and the presence of certain risk genotypes. In adults the same situation is often referred to as latent autoimmune diabetes in adults (LADA). We tested whether genetic markers associated with type 1 or type 2 diabetes could help to discriminate between autoimmune and non-autoimmune diab
Böcker, dagstidningar och lagrad information, t.ex. cd-skivor, fyller inte sin funktion som det självklara valet för en stor del i dagens moderna samhälle där det ska gå fort att få tag i uppdaterad information. Valet för många är Internet, där man kan få tag i aktuell information endast genom att par enkla musklick. Det är inte enbart för individen möjligheterna finns att ta del av den senaste in
The taxation of the digital economy has become a relevant subject, as business models and value creation chains of all sectors have been transformed bringing challenges to the international tax system and parameters for the allocation of taxing rights between source and residence jurisdictions. In view of these changes, the European Commission has published two proposals for directives on the taxa
The Swedish household debt has been quite high and increasing for the past 30 years. In this thesis I tried to find the underlying reasons for the development in the long-run by using the Engle-Granger two-step model for co-integration but found that there was no co-integration between the household debt to disposable income ratio and the chosen variables. In the short-run analysis I de-trended al
En förutsättning för att ett beteende ska kriminaliseras är att det tänkta straffbudet avser ett identifierat och konkretiserat intresse som är skyddsvärt, det vill säga godtagbart. Ett godtagbart skyddsintresse kan definieras som det värde som skyddas i ett visst straffbud. Föreställningarna om skyddsintresse har systematisk betydelse för indelningen av brottstyper. Att finna arten av det intressA prerequisite for a behavior to be criminalized is that the intended criminal law provision applies to an identified and concretized interest that should be protected. An acceptable protective interest can be defined as the value protected in a particular criminal law provision. The concepts of protective interests have a systematic significance for the classification of the type of crime. Determ
Climate change will alter the hydrological cycle in the 21st century with implications for the water balance and water quality. As characteristics of the landscape may vary significantly between nearby locations, hydrological models need to be able to delineate responses attributed to specific landscape characteristics, to estimate their responses to altered climatic drivers. Small streams are the
Syftet med uppsatsen är att redogöra för svensk rätt avseende ogiltighet av vilseledande avtal i förhållande till bluffakturor. Sedan tio år tillbaka har antalet polisanmälningar ökat markant rörande just bluffakturor, då finns det även ett stort mörkertal. Förutom att det drabbar många, är det betydande summor som årligen omsätts på grund av detta, således är detta ett ämne som förtjänar att belyThe purpose of this paper is to display Swedish law in regards to fake invoices and how these contracts under misleading agreements can be voided. The amount of police reports regarding fake invoices have increased significantly during the last ten years, one should also consider the big number of hidden statistics. Apart from the fact that it affects a lot of people it also has a high yearly turn
This study presents reconstructions of black carbon (BC), including spheroidal and amorphous carbonaceous particles (SCP and ACP), organic matter (OM; total organic carbon, TOC; total nitrogen, TN; total sulfur, TS), and heavy metals (Fe, Zn, Pb, Cu, As and Hg) in coastal sediments off the south-west coast of Sweden. Sediment records from eight stations along a north-south transect off the south-w
In order to fully understand the underlying processes of catalysis, it is vital to combine measurements of the catalyst surface, where the reaction occurs, with measurements of the gas concentration close to the catalyst. We have developed a convenient setup, which uses a single laser system to visualise the gas surrounding a working catalyst in situ at realistic operating conditions. Planar Lase
Leukemia is the most common type of cancer in children, with B-cell acute lymphocytic leukemia (B-ALL) being a common type in both children and adults. Different types of treatments are available, such as chemotherapy, stem cell treatment and immunotherapy. However, a recurring problem is relapses, with the survival rate after relapse being very low. In combating this issue new methods have been d
Aircraft observations of precipitating clouds with cloud top temperatures higher than -38°C have revealed that Secondary Ice Production (SIP) is responsible for presence of majority of ice particles. One such SIP mechanism is fragmentation via collisions between ice particles. The central theme of this study is to understand the dependencies of this SIP mechanism and improve its existing numerical
This master thesis project was performed in collaboration with Johnson Matthey. Johnson Matthey is a worldwide company working with sustainable technologies. The site in Perstorp, where this work was performed, focus on formaldehyde production. In order to continuously improve chemical processes, simulation and modeling are advantageous tools. They can give a better understanding of the processes
Heterologous overexpression of proteins signifies that the encoding gene of a protein in one organism is expressed in another host organism that normally does not have that gene in its genome. In basic biochemical research, this is an important method for studying various protein functions such as activity and interactions in biological processes, as well as obtaining sufficient amounts to determi
1. In a correlative study, we investigated the relative importance of fish predation, refuge availability and resource supply in determining the abundance and size distributions of the introduced and omnivorous signal crayfish (Pacifastacus leniusculus) in lakes and streams. Moreover, the biomass and food selection of predatory fish was estimated in each habitat type and stable isotopes of carbon
Large increases in regional cerebral blood flow (rCBF) have been measured in patients with Parkinson's disease (PD) following the administration of L-DOPA, but the underlying mechanisms have remained unknown. In this study, we have used rats with unilateral 6-hydroxydopamine (6-OHDA) lesions as a model of PD in order to compare the patterns of rCBF and regional cerebral glucose utilisation (rCGU)
Popular Abstract in Swedish Förmågan att planera med en medveten mental simulering har ansetts vara unikt mänsklig sedan Aristoteles. När människor planerar för psykologiska eller fysiologiska driftstillstånd som de för närvarande inte upplever, tror man att de använder sig av så kallad episodisk framförhållning. Den episodiska framförhållningen är en del av det större episodiska kognitiva systemeThe ability to plan for future, not currently experienced, mental or physiological states has been regarded as unique to humans. When humans plan for such states it has been hypothesized that they make use of what has been known as episodic foresight. Episodic foresight is a part of the episodic cognitive system, which also includes episodic memory. The defining feature of this system is so-called
Objective: We used dual X-ray absorptiometry (DXA) to measure calcaneal bone mineral density (BMD) and estimate the prevalence of osteoporosis in a population with distal forearm fracture and a normative cohort. Methods: Patients 20 to 80 years of age with distal forearm fracture treated at one emergency hospital during two consecutive years were invited to calcaneal BMD measurement; 270 women (81
BackgroundInflammation and tyrosine-kinases are known mediators in the pathobiology of cardiovascular disease. Plasma biomarkers reflecting these systems may provide a noninvasive complement reflecting hemodynamics, aiding in clinical decision-making. We therefore aimed to investigate the plasma levels of vascular and inflammatory proteins, and their associations with invasive hemodynamics in adva
Background: Rare variants of the triggering receptor expressed on myeloid cell 2 (TREM2) gene are strong risk factors for Alzheimer’s disease (AD), and drugs targeting the TREM2 protein are being developed. However, it is unknown what the effect of TREM2 variants is on the AD phenotype. Methods: Here we studied a full range of clinical and biomarker measures in a large cohort of TREM2 variant carr
