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Background: Earlier studies have found a positive effect of alcohol consumption, with a reduced disease activity in rheumatoid arthritis (RA). The aim of this study was to assess alcohol consumption and its association with disease activity and health related quality of life (HRQL) in Swedish RA patients. Methods: Between 1992 and 2005, 2,800 adult patients were included in the BARFOT study of ear
Background Families with parental intellectual disabilities (ID) are likely to need support in achieving a decent family life. In order to accurately plan for such support services, society needs data regarding the occurrence of those parents and their children. The aim of this study was to investigate the 5-year incidence of children born to women with ID in a county in Sweden. Methods Women born
A search is presented for direct top squark pair production in final states with one isolated electron or muon, jets, and missing transverse momentum in proton-proton collisions at root s = 7 TeV. The measurement is based on 4.7 fb(-1) of data collected with the ATLAS detector at the LHC. Each top squark is assumed to decay to a top quark and the lightest supersymmetric particle (LSP). The data ar
The Fontan procedure has improved survival in children with functionally univentricular hearts. With time, however, complications such as reduced exercise capacity are seen more frequently. Exercise intolerance is multifactorial, but pulmonary vascular resistance probably plays a crucial role. Elevated pulmonary vascular resistance has been associated with raised levels of endothelin-1, which are
Popular Abstract in Swedish Syftet med undersökningen är att beskriva de livsförändringsprocesser som blir nödvändiga då en person drabbas av kronisk sjukdom eller ett funktionshinder. Vad innebär det att drabbas av en kronisk sjukdom eller ett funktionshinder? Hur lär man sig leva med de nya livsvillkoren? Dessa frågor belyses utifrån intervjuer med kvinnor som drabbats av kronisk smärta (fibromThe aim of this thesis is to study the life-changing processes necessary when a person is faced with the demands caused by chronic illness or disability. As subjects for the study, women with chronic pain (fibromyalgi and myofascial pain syndrome), were chosen. Eighteen women active in working life were interviewed on two occasions, with an interval of two months. The women have been living with t
To describe the Avodart after Radical Therapy for prostate cancer Study (ARTS), investigating the use of dutasteride (a dual 5 alpha-reductase inhibitor that suppresses intraprostatic dihydrotestosterone, reduces tumour volume and improves other markers of tumour regression in prostate cancer) to prevent or delay disease progression in patients with biochemical recurrence after therapy with curati
Objective. To analyze the genetic impact of allelic variants of the protein tyrosine phosphatase N22 (PTPN22) and HLA-DRB1 alleles on IgG autoantibody formation directed toward an immunodominant conformational epitope (C1(III); amino acid residues 359-369) of type 11 collagen (CII) in early rheumatoid arthritis (RA). Methods. Sera obtained at study inclusion from an inception cohort of RA patients
Most models to predict biochemical recurrence (BCR) of prostate cancer use pretreatment serum prostate-specific antigen (PSA), clinical stage and prostate biopsy Gleason grade. We investigated whether human glandular kallikrein 2 (hK2) and free prostate-specific antigen (fPSA) measured in pretreatment serum enhance prediction. We retrospectively measured total PSA (tPSA), fPSA and hK2 in preoperat
BACKGROUND: Mortality caused by acute pancreatitis in patients admitted to the hospital has been thoroughly investigated, but knowledge regarding outpatient fatalities is far from complete. The purpose of this study was to assess the incidence and clinical characteristics of patients who have died due to acute pancreatitis occurring outside the hospital. METHODS: Deaths caused by acute pancreatiti
BACKGROUND: Evaluation of stress-induced ST deviations constitutes a central part when interpreting the findings from an exercise test. The aim of this analysis was to assess the pathophysiologic correlate of stress-induced ST elevation and ST depression with regard to presence, amount and location of myocardial ischemia as assessed by myocardial perfusion SPECT (MPS) in patients with suspected co
PURPOSE: The partial volume effect (PVE) is an important source of bias in brain perfusion measurements. The impact of tissue PVEs in perfusion measurements with dynamic susceptibility contrast MRI (DSC-MRI) has not yet been well established. The purpose of this study was to suggest a partial volume correction (PVC) approach for DSC-MRI and to study how PVC affects DSC-MRI perfusion results.METHOD
The development of EuroQol-5 dimensions (EQ-5D) utility over time in rheumatoid arthritis (RA) patients, treated with biologics other than tumour necrosis factor inhibitors (TNFi), based on the standard British (UK) and the new Swedish (SE) EQ-5D preference sets, has not been previously described.
To understand the origin of disease risk in adulthood, factors in all stages of life and on different contextual levels should be considered. Therefore, the aim of this study was to investigate the relevance of a person's area of residence over their life course with regard to four outcomes: all-cause mortality; ischemic heart disease mortality and morbidity; cancer mortality and morbidity; and re
In industries like high-tech and automotive, increasingly more of the product value delivered to the customer is based on a combination of hardware (HW) and software (SW), where SW handles much of the differentiation of capacity and features. The “logistics process” of SW, especially when it merges with HW along the process, has so far been little studied but a problem noticed is the difficulties
Objective. To compare the effects of a restrictive versus a liberal fluid prescription, on quality of life, physical capacity, thirst and hospital admissions, in patients who had improved from NYHA class (III-)IV CHF to a stable condition without clinical signs of significant fluid overload. Design. The present study is a randomised cross-over study. Seventy-four patients (mean age 70 +/- 10 years
Syftet med denna studie är att finna verktyg för att kunna arbeta med musikskapande med elever som har en funktionsnedsättning. Det är en kvalitativ fallstudie där vi följer en musiklärare och en elev. Data är insamlat genom klassrumsobservationer och intervjuer. Jag börjar med att presentera den teorietiska bakgrunden och refererar till litteratur om funktionsnedsättningar och musik och musikskapTitle: Calling out - creative music making for everyone! A study about a music teacher and a pupil with a physical disability working together with creative music making. The purpose of this study is to investigate tools for working with creative music making with pupils with physical impairments. In a qualitative case study we follow one music teacher and one student in primary school. Data was c
This research explores the development and use of waste to energy (WTE) technologies in Europe and in the Province of Ontario, Canada. As the quantity of waste generated has continued to increase in industrialized countries, the need for alternative waste management methods to reduce the dependency on landfill and to recover the resource in the waste has also increased. Many European countries, in
