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Objective and Background: Pulse wave amplitude (PWA) derived from the digital vascular bed has been used in sleep studies. The nocturnal attenuation of PWA has been shown to reflect sympathetic activation during sleep. We assessed the relationship between nocturnal PWA attenuation and office blood pressure (BP). Methods: Eighty-one subjects (46 men; age 60 7 years: body mass index [BMI] 28.2 +/- 4
In an attempt to define clinically relevant models of akinesia and dyskinesia in 6-hydroxydopamine (6-OHDA)-lesioned rats, we have examined the effects of drugs with high (L-DOPA) vs. low (bromocriptine) dyskinesiogenic potential in Parkinson's disease on three types of motor performance, namely: (i) abnormal involuntary movements (AIMs) (ii) rotational behaviour, and (iii) spontaneous forelimb us
Anesthetized, paralyzed and mechanically ventilated pigs were exposed to extreme hypercapnia (PaCO2 approximately 20 kPa) at FiO2 0.4 for 480 min, with (n = 6) or without (n = 6) continuous infusion of isotonic buffers (bicarbonate and trometamol). Arterial pH was higher in buffered animals than controls, 7.21 +/- 0.01 vs 7.01 +/- 0.01 (mean +/- s.e.mean, P < 0.01). Serum osmolality and PaCO2 did
The evidence for anthropometric factors influencing breast cancer risk is accumulating, but uncertainties remain concerning the role of fat distribution and potential effect modifiers. We used data from 73,542 premenopausal and 103,344 postmenopausal women from 9 European countries, taking part in the EPIC study. RRs from Cox regression models were calculated, using measured height, weight, BMI an
Object: To present population-based and age related incidence of surgery and clinical outcome for adult patients operated for hydrocephalus, registered in the Swedish Hydrocephalus Quality Registry (SHQR). Methods: All patients registered in SHQR during 2004–2011 were included. Data on age, gender, type of hydrocephalus and type of surgery were extracted as well as three months outcome for patient
Treatment with pancreatic or pancreatic-like microbial enzymes during the suckling period has positive effects on the gut, resulting in a better fat absorption and improved barrier function in pigs. The present study investigated the effects of pancreaticlike enzyme treatment during the pre- or postweaning period on pig growth and nitrogen utilization. Suckling 7- to 14-d-old pigs were gavage fed
Purpose: We investigated the value of serum measurements for glandular kallikrein 2 (hK2), and free (f) and total (t) prostate specific antigen (PSA) in a second round of biannual screening for prostate cancer. Materials and Methods: In 1995 to 1996, 5,853 of 9,811 randomly selected men in Goteborg, Sweden 50 to 66 years old had PSA measurements. Of 660 men 611 with tPSA 3 ng/ml or greater underwe
Recent research on life in extreme environments has shown that some microorganisms metabolize at extremely low temperatures in Arctic and Antarctic ice and permafrost. Here, we present kinetic data on CO2 and (CO2)-C-14 release from intact and C-14-glucose amended tundra soils (Barrow, Alaska) incubated for up to a year at 0 to -39 degrees C. The rate of CO2 production declined exponentially with
BACKGROUND/AIMS: Endoscopic sphincterotomy is an established treatment of retained or recurrent common bile duct calculi after cholecystectomy and in the majority of patients with an intact gallbladder. In order to identify patients ultimately requiring additional endoscopic procedures or surgery, factors predictive of decreased endoscopic bile duct clearance were sought. MATERIAL AND METHODS: Bet
Respiratory tract deposition data of ultrafine aerosol particles, hygroscopic particles and ambient particles in general are scarce. Measurements are associated with several difficulties. The objective of this work was to design a method for fast determination of highly size-resolved fine and ultrafine particle deposition, to be used on larger groups of human subjects in exposure studies and in ty
Research on InterStellar Objects (ISOs) has been done for several decades, however, the first observed ISO in the Solar system was only recently discovered in 2017. It was named 1I/'Oumuamua and was only passing though the Solar system, but this may not be the case for all objects of its kind. For instance, one could gain a bound orbit around the Sun if the right amount of nudge is acquired wh
Back-arc volcanism in the western Argentinian provinces of Mendoza and Neuquen has been widespread from the Miocene to historic times. We present a detailed investigation of profiles through two of the major Miocene volcanic areas of the region, the neighboring Huantraico and La Matancilla plateaus, including new Ar-40/Ar-39 age results of major and trace elements as well as Nd, Sr and Pb isotopic
Male breast cancer is poorly understood with a large proportion arising in the familial context particularly with the BRCA2 germline mutation. As phenotypic and genotypic differences between sporadic and familial male breast cancers have been noted, we investigated the importance of a hypoxic drive in these cancers as this pathway has been shown to be of importance in familial female breast cancer
Laser diagnostic techniques have for more than 30 years added very valuable input for a deepened understanding of combustion processes. The present paper will focus on techniques developed for visualization of important parameters with the ability to get detailed information in space and time. The paper is not meant to be a complete review of the entire research field but rather a survey with a ma
In multi-user multiple input multiple output (MU-MIMO), the complexity of the base-station scheduler has increased further compared to single-user multiple input multiple output (SU-MIMO). The scheduler must understand if several users can be spatially multiplexed in the same time-frequency resource. One way to spatially separate users is through beamforming with sufficiently many antennas. In thi
The North Atlantic Oscillation (NAO), a measure of the strength of the zonal wind across the North Atlantic Ocean, strongly influences weather conditions in NW Europe, e.g. temperature, precipitation and wind, especially during winter. It was hypothesised that elevated concentrations of nitrogen oxides in Gothenburg would be enhanced during negative NAO index (NAOI) conditions, representing more a
Background: Foods with a low glycemic index are increasingly being acknowledged as beneficial in relation to the insulin resistance syndrome. Certain organic acids can lower the glycemic index of bread products. However, the possible effect of acids in fermented milk products on the glycemic index and on insulinemic characteristics has not been addressed. The metabolic effects of fermented milk or
BACKGROUND: An early age at menarche, a short menstrual cycle length, and a high age at first full term pregnancy or nulliparity are known risk factors for breast cancer. These risk factors have previously been reported to differ between breast cancer patients with and without a family history of breast cancer and also between breast cancer patients and controls. METHODS: Self-administered questio
BACKGROUND: Individuals with low income have poorer health and should, therefore, have higher health expenditure than people with high income particularly in countries with a universal health care system. However, it has been discussed if social inequities in health diminish with age and we, hence, aimed to analyse this question. METHODS: We performed an age stratified cross-sectional analysis usi
