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This study uses the model of Jamieson, Chapelle and Preiss, along with the extended theories of Chapelle, to evaluate a tool for learning french online, more specifically the Coffee Break French Podcast. The method employed is dual: an expert analysis based on a profound study of the material, and a survey sent to a set of the podcast users. The study finds that the podcasts, along with its supple

Optimising performance in clinical capsule endoscopy

Video capsule endoscopy (VCE), perfomed by ingesting a small vitamin-sized camera pill, was developed over a period of a couple of decades and –since its introduction in clinical practice at the dawn of the millennium– has become an essential tool in the diagnosis and management of small bowel (SB) diseases. At the same time, other fields such as minimally invasive diagnosis of other parts of the

DNA building blocks: keeping control of manufacture

Ribonucleotide reductase (RNR) is the only source for de novo production of the four deoxyribonucleoside triphosphate (dNTP) building blocks needed for DNA synthesis and repair. It is crucial that these dNTP pools are carefully balanced, since mutation rates increase when dNTP levels are either unbalanced or elevated. RNR is the major player in this homeostasis, and with its four different substra

Studies of bacterial surface proteins interacting with the immune system

Popular Abstract in Swedish En av de viktigaste substanserna i vår kropp är proteiner, också kallade äggviteämnen. Proteiner har en mängd olika uppgifter i kroppen, de finns i våra celler där de har olika uppgifter såsom att fungera som enzymer, transportörer, signalsubstanser, eller som skyddsfaktorer. Proteiner ingår också som viktiga beståndsdelar i vävnaderna mellan cellerna och finns dessutomPathogenic bacteria express a wide array of surface proteins that interact with the environment. Many of these proteins are believed to be important for the virulence. This thesis deals with the binding of immunoglobulins (Ig) and complement regulating proteins to certain bacterial surface proteins. Protein L from Peptostreptococcus magnus binds to Igk-light chains while protein A from Staphylococ

COSB50 Course Outline Fall 2021

1 CÖSB50: Contemporary Japanese Society, 7.5 Credits Fall Semester 2021 2021-11-02 – 2020-12-01 Venue: In class and Zoom Course Director: Ernils Larsson E-mail: ernils.larsson@ace.lu.se Office hours: By appointment, via Zoom This outline is provisional, and subject to change, as the situation changes. Course Content This course examines contemporary Japanese society, focusing on issues such as pol

https://www.ace.lu.se/sites/ace.lu.se/files/2021-10/COSB50%20Course%20Outline%20Fall%202021.pdf - 2026-05-27

Studies on Neuropsychiatric Manifestations and Genetic Factors in Systemic Lupus Erythematosus

Background: Systemic Lupus Erythematosus (SLE) is an autoimmune disease encompassing a wide range of symptoms that can emanate from pathology in virtually any organ system. Severe SLE includes involvement of the central nervous system and kidneys. One of the hallmarks of the disease is a multitude of autoantibodies, indicating a breakdown in self tolerance. The corresponding antigens have been fou

The molecular basis of human igg-mediated enhancement of C4b-binding protein recruitment to group a streptococcus

Streptococcus pyogenes infects over 700 million people worldwide annually. Immune evasion strategies employed by the bacteria include binding of the complement inhibitors, C4b-binding protein (C4BP) and Factor H in a human-specific manner. We recently showed that human IgG increased C4BP binding to the bacterial surface, which promoted streptococcal immune evasion and increased mortality in mice.