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Osteoarthritis of the carpometacarpal joint at the base of the thumb (CMC1 OA) is common and causes difficulty in grasp, grip, and fine manipulation of the hand. Surgery is recommended after failure of non-operative treatment, andevidence from short and medium-term follow-up studies shows successful relief of pain and return of function. Previous investigations of epidemiology and risk factors wer

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Pollination is a key ecosystem service for global agriculture but evidence of pollinator population declines is growing. Reliable spatial modelling of pollinator abundance is essential if we are to identify areas at risk of pollination service deficit and effectively target resources to support pollinator populations. Many models exist which predict pollinator abundance but few have been calibrate

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Biomarkers are used in molecular biology to predict characteristics of interest and are applied in agriculture to accelerate the breeding of target traits. Proteomics has emerged as a promising technology for improved markers by providing a closer view to the phenotype than conventional genome-based approaches. However, a major challenge for biomarker development is that the identified biological

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Afhandlingens empiriske udgangspunkt er Bornholms vikingetidsskatte (ca. 850-ca. 1150), med særlig fokus på 34 udgravede lokaliteter, der i hidtil uset skala gør det muligt, at inddrage den arkæologiske kontekst i tolkningen af skattenes betydninger. I afhandlingen opstilles tre forskningsspørgsmål: 1) Afspejler skattene de mennesker, der akkumulerede, håndterede og deponerede dem, og er det mulig

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Purpose: To evaluate and increase the efficiency of the internal processes by clearly visualizing the information flow and present improvement suggestions at Vestas Northern Europe.
Problem definition: To clearly define what information is shared today, identify where the critical interfaces take place and where vital information is lost.
Method: This study takes a her

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Sweden’s grocery distribution is routed through a limited number of upstream hubs and relies on corridors and ferry links. When disruptions affect a hub or a critical link, reallocations propagate fast and travel times increase, with some areas losing coverage temporarily. Decentralising the whole system is costly, so targeted resilience options must be evaluated. The purpose of this thesis is to

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Throughout history, human civilisation and wildlife have instinctively settled close to water and coastlines out of necessity for resources. It has always been a natural instinct, yet we have also continually adapted to weather conditions and relocated when resources were found elsewhere. We have always been flexible and mobile, adapting to nature and allowing it to lead and guide us. With the ris

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GPS tracking technologies are essential to follow long-distance migratory species throughout their annual cycle and identify the threats they encounter at large geographical scales. Information on the “lost” years of juvenile individuals of many species is lacking and it is vital to uncover their movements during these critical early stages. The Baltic Lesser Black-backed Gull (L. f. fuscus), a lo

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Uppsatsen behandlar hur miljörelaterade fordringar hanteras när en verksamhet går i konkurs och i vilken utsträckning principen om att förorenaren ska betala får genomslag i svensk konkursrätt. Utgångspunkten är de praktiska problem som uppstår när kostsamma efterbehandlingsåtgärder aktualiseras först efter konkursutbrottet, samtidigt som det inte finns någon generell skyldighet för staten eller kThis thesis examines how environmental claims are treated when a business is declared bankrupt, and to what extent the polluter pays principle is upheld in Swedish bankruptcy law. The point of departure is the practical difficulties that occur when costly remediation measures become relevant only after the opening of bankruptcy proceedings, while there is no general legal obligation for the State

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Scientific summary: Ground settlement due to groundwater drainage during construction is important to be considered since ground settlement may cause severe building damages. The calculation of ground settlement contained several parameters with different magnitude of uncertainties. Thus a risk evaluation of ground settlement is necessary. The aim of this thesis was first to build a soil strata mo

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Denna avhandling undersöker hur aktörer i Stilla havet producerade och spred oppositionell kunskap om kärnvapentester från 1950-talet till början av 2000-talet, med Franska Polynesien i fokus. För att analysera detta lanseras begreppet vittnesaktivism som övergripande står för organiserade praktiker av vittnesmål, dokumentinsamling, arkivering och transnationell spridning, genom vilka aktörer utmaThis dissertation examines how actors in the Pacific produced, mobilized, and circulated oppositional knowledge about nuclear weapons testing from the 1950s to the early 2000s, with French Polynesia as its primary focus. At its core is witness activism: coordinated practices of testimony, document retrieval and annotation, archiving, publication, and transnational circulation through which activis

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This thesis examines the economic potential of lithium-ion battery storage systems in multi-family residential buildings in Sweden, focusing on profitability, revenue opportunities, and the factors influencing investment decisions. The increasing share of renewable electricity, combined with the electrification of society, has intensified the need for energy storage solutions capable of balancing

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Ett förändrat nederbördsklimat i kombination med ökade trafikbelastningar ställer nya krav på vägkonstruktioners utformning och funktion. Syftet med denna litteraturstudie är att undersöka hur vägkonstruktioner påverkas av kraftig nederbörd och tung belastning, samt att analysera skillnader mellan moderna och äldre konstruktioner avseende lastupptagning och vattenhantering. Vidare behandlas hur daA changing precipitation pattern, characterized by shorter but more intense rainfall events, combined with increasing traffic loads, places new demands on road construction design and performance. The aim of this literature study is to investigate how road structures are affected by heavy rainfall and increased loading, as well as to analyse differences between modern and older road constructions

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Bygg- och anläggningsprojekt genererar stora mängder schaktmassor, den årliga mängden som uppstår är cirka 60–200 miljoner ton (Naturvårdsverket, 2024). Schaktmassorna behöver hanteras och omhändertas vilket kan innebära att de återanvänds på den plats de uppstått eller att de transporteras bort för att hanteras på annan plats. Däremot kan massorna vara förorenade vilket ställer till problem, exem

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Karst caves are known to buffer external climatic variability and track annual temperature and humidity means, yet little is understood about how this buffering extends beyond cave interiors or whether it influences vegetation patterns at cave entrances. This pilot study investigates microclimate (temperature, relative humidity and derived vapour pressure deficit) and vegetation patterns (Shannon

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Laccases are multicopper oxidases capable of oxidizing a broad range of phenolic and non-phenolic compounds, making them attractive biocatalysts for lignin valorization and environmental applications. In this work, two bacterial laccases, LacA from Bacillus amyloliquefaciens and MEK from Psychrobacter sp., were recombinantly produced in Escherichia coli BL21 (DE3), purified, and characterized to s

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This study examines the relationship between video games exposure and political attitudes among young adults in Sweden. As video games have become one of the most prominent forms of contemporary popular culture and entertainment media, and Sweden ranks as one of Europe’s most founded gaming industries. It is important to understand whether gaming engagement is associated with political socialisati

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Introduction: Ovarian cancer is a lethal disease with low survival rates for women diagnosed in advanced stages. Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. The β-galactoside-binding lectin, Galectin-3, is involved in different immune processes and has been associated with poor outcome in various cancer