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Persistence of grassland plants - Site, landscape and species properties influencing extinction and persistence of plants in semi-natural grasslands in south Sweden

Semi-natural grasslands in Scandinavia have been created by humans since many millennia ago, but the agricultural intensification in the last few centuries caused them to decline heavily. Accordingly, the biodiversity associated to these open, nutrient-poor habitats declined as well and many remnant populations are slowly declining and threatened to go extinct. In this study, I focused on declin

Assessing Great Britain as a relocation site for the threatened Iberian Lynx in a changing climate

The Iberian Lynx (Lynx pardinus) faces imminent endangerment due to climate change resulting in the declining population of its primary prey, the European Rabbit (Oryctolagus cuniculus). With ongoing environmental shifts, this threat intensifies, heightening the risk of extinction for the species. The aim of this study was to explore a potential conservation strategy; the possibility of relocating

Instrumentation of multilevel systems with transducers to characterize hydrogeological conditions at a PCE and TCE contaminated site in Helsingborg, Sweden

Detaljerade data är avgörande vid karaktärisering av komplexa förorenade områden. I denna studie utrustar vi ett antal G360-brunnssystem med Star-Oddi milli-TD-tryckgivare i ett mestadels PCE (tetrakloretylen)- och TCE (trikloretylen)-förorenat bostadsområde i Helsingborg. Trots att dessa tryckgivare vanligtvis används inom marina undersökningar gör deras kostnad samt kompakta storlek dem av intre

Inferring the migratory status of woodland birds usisng ringing data: the case of a constant-effort site located in the Iberian highlands.

Understanding the spatiotemporal distribution of birds is crucial for effective management and conservation of their populations. However, we still have only limited knowledge not only of the wintering destinations of many Iberian breeding migrants but also of aspects as general as the migratory behaviour of the populations of many common avian species that breed in the Iberian highlands. We used

Temporal filtering and time-lapse inversion of geoelectrical data for long-term monitoring with application to a chlorinated hydrocarbon contaminated site

We present a solution for long-term direct current resistivity and time-domain induced polarization (DCIP) monitoring, which consists of a monitoring system and the associated software that automates the data collection and processing. This paper describes the acquisition system that is used for remote data collection and then introduces the routines that have been developed for pre-processing of

Air pollution online : Everyday environmental information on the social media site Sina Weibo

Purpose: This study explores how information on air pollution is shaped online on an everyday basis, with a particular emphasis on digital devices and digital representations as constitutive of environmental information practices. Furthermore, this research highlights an understudied aspect of air pollution – the digital flow of multimodal representations that citizens encounter and produce in the

QM/MM Study of the Catalytic Reaction of Myrosinase; Importance of Assigning Proper Protonation States of Active-Site Residues

Myrosinase from Sinapis alba hydrolyzes glycosidic bonds of β-d-S-glucosides. The enzyme shows an enhanced activity in the presence of l-ascorbic acid. In this work, we employed combined quantum mechanical and molecular mechanical (QM/MM) calculations and molecular dynamics simulations to study the catalytic reaction of wild-type myrosinase and its E464A, Q187A, and Q187E mutants. Test calculation

Secondary nucleation and elongation occur at different sites on Alzheimer's amyloid-b aggregates

The aggregates of the Ab peptide associated with Alzheimer's disease are able to both grow in size aswell as generate, through secondary nucleation, new small oligomeric species, that are major cytotoxins associated with neuronal death. Despite the importance of these amyloid fibril-dependent processes, their structural and molecular underpinnings have remained challenging to elucidate. Here, we c

Intercomparison of eddy-covariance software for urban tall-tower sites

Long-term tall-tower eddy-covariance (EC) measurements have been recently established in three European pilot cities as part of the ICOS-Cities project. We conducted a comparison of EC software to ensure a reliable generation of interoperable flux estimates, which is the prerequisite for avoiding methodological biases and improving the comparability of the results. We analyzed datasets covering 5

Position of Deltaproteobacteria Cas12e nuclease cleavage sites depends on spacer length of guide RNA

Cas12e proteins (formerly CasX) form a distinct subtype of Class II type V CRISPR-Cas effectors. Recently, it was shown that DpbCas12e from Deltaproteobacteria and PlmCas12e from Planctomycetes can introduce programmable double-stranded breaks in mammalian genomes. Thus, along with Cas9 and Cas12a Class II effectors, Cas12e could be harnessed for genome editing and engineering. The location of cle

Quantum refinement with electron diffraction and X-ray free-electron laser data: comparative study of ribonucleotide reductase dimetal site

Quantum refinement (QR) is an approach in which the empirical restraints used in standard structural refinement to ensure that the details of the structure, e.g. bond lengths and angles, make chemical sense are replaced by more accurate quantum mechanical calculations for a small but interesting part of the structure. QR has previously been used for X-ray and neutron crystallography, cryogenic e

Wildfire and post-fire management reshape soil microbial guilds and carbon dynamics at a boreal forest site in Sweden

Wildfires are a natural disturbance shaping boreal forests, but their effects on soil microbial communities and biogeochemical cycling remain unclear, particularly in Fennoscandia. We investigated the impact of fire severity and post-fire management on the soil microbial community two years after a boreal wildfire in Sweden. We quantified growth rates of bacteria, saprotrophic fungi (SF), ectomyco

Case report of a novel homozygous splice site mutation in PLA2G6 gene causing infantile neuroaxonal dystrophy in a Sudanese family

Background: Infantile neuroaxonal dystrophy (INAD) is a rare hereditary neurological disorder caused by mutations in PLA2G6. The disease commonly affects children below 3 years of age and presents with delay in motor skills, optic atrophy and progressive spastic tetraparesis. Studies of INAD in Africa are extremely rare, and genetic studies from Sub Saharan Africa are almost non-existent. Case pre

The dark matter of the cancer genome : Aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations

Cancer is a disease of the genome caused by oncogene activation and tumor suppressor gene inhibition. Deep sequencing studies including large consortia such as TCGA and ICGC identified numerous tumor-specific mutations not only in protein-coding sequences but also in non-coding sequences. Although 98% of the genome is not translated into proteins, most studies have neglected the information hidden

M(III) Site-Driven Structural Engineering on Lead-Free Layered Double Perovskite Nanocrystals with Enhanced Photoelectrochemical Activity

Over the past decade, organic–inorganic hybrid perovskites have revolutionized next-generation semiconductors, driving unprecedented advancements in cost-effective optoelectronics. While lead-based perovskite semiconductors exhibit exceptional optoelectronic properties, their inherent toxicity and vulnerability to environmental degradation remain significant barriers to widespread commercializ

Site selection for nature-based solutions for stormwater management in urban areas : An approach combining GIS and multi-criteria analysis

In recent years, particularly following the definition of the UN Sustainable Development Goals (SDGs) for 2030, Nature-Based Solutions (NBS) have gained considerable attention, capturing the interest of both the scientific community and policymakers committed to addressing urban environmental issues. However, the need for studies to guide decision-makers in identifying suitable locations for NBS i

Ground-State Destabilization by Active-Site Hydrophobicity Controls the Selectivity of a Cofactor-Free Decarboxylase

Bacterial arylmalonate decarboxylase (AMDase) and evolved variants have become a valuable tool with which to access both enantiomers of a broad range of chiral arylaliphatic acids with high optical purity. Yet, the molecular principles responsible for the substrate scope, activity, and selectivity of this enzyme are only poorly understood to date, greatly hampering the predictability and design of