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The effect of strain and transforming growth factor beta on equine tendon fibroblasts (tenocytes) was assessed in vitro. Tenocytes were isolated from flexor and extensor tendons of horses from foetal to 10 years of age. These cells were cultured until confluent on collagen-coated silicone dishes. Cyclic biaxial strain of 9 +/- 1% was applied at 0.5 Hz for 24 hours with or without added TGFbeta1 or
Background/Aims: We have observed a difference between patients on low-flux hemodialysis (HD) or peritoneal dialysis and patients on hemodiafiltration (HDF) or high-flux HD in the capacity of transmigrated leukocytes to mobilize CD11b in response to inflammatory stimuli compared with healthy subjects. This could be due to different interstitial chemokine concentrations. Methods: We measured concen
Ligand induced activation of the beta-receptor for platelet-derived growth factor (PDGF) leads to activation of Src family tyrosine kinases. We have explored the possibility that the receptor itself is a substrate for Src. We show that Tyr934 in the kinase domain of the PDGF receptor is phosphorylated by Src. Cell lines expressing a beta-receptor mutant, in which Tyr934 was replaced with a phenyal
Each autumn, large numbers of red admirals migrate throughout northern Europe,flying south, to reach areas with conditions suitable for surviving the winter. We observed the visible butterfly migration at Falsterbo peninsula, the southwesternmost point in Sweden, where red admirals are seen most autumns. ying towards the Danish coast on their way to more southern parts of Europe. Weather parameter
-Reduced arterial compliance precedes changes in blood pressure, which may be mediated through alterations in vessel wall matrix composition. We investigated the effect of the collagen type I-alpha1 gene (COL1A1) +2046G>T polymorphism on arterial compliance in healthy individuals. We recruited 489 subjects (251 men and 238 women; mean age, 22.6+/-1.6 years). COL1A1 genotypes were determined using
This article outlines an experimental and numerical study of basic creep in High Performance Concrete. About 100 cylinders (studies of creep and shrinkage) and 400 cubes (for studies of hydration, internal relative humidity, and strength) were tested. The ambient climate was held constant at 20°C. One concrete was studied at other temperatures between -20°C and 60°C. Analyses were carried out of q
Abstract in Spanish Los rituales indígenas acompañaron a Evo Morales a través de sus primeros años como presidente de Bolivia. El oficio y las prácticas rituales del curandero y sabio aymara, el yatiri, están pasando por interesantes transformaciones, entrando a espacios políticos donde no solían estar presentes. ¿Pero cuál es realmente el papel que juegan el conocimiento terapéutico y la prácticaIndigenous rituals escorted Evo Morales throughout his first years as president of Bolivia. The art and the ritual practices of the yatiri, the Aymara healer and ritual specialist, are going through interesting transformations entering new political spaces of power. But which role does this therapeutic knowledge and ritual practice actually play in the present political process and how should this
Environmental psychology conducts research, teaching and collaborations focused on the interaction between people and the environment from the perspective of the individual. The subject deals with how people experience their surroundings and are affected by them, as well as how humans affect the environment through their behaviour. The research encompasses the relationship to both the physical a
Bacteria and humans have co-evolved since their common existence. They have thereby developed very specific defence and target mechanisms against one another. Understanding the complex biomolecular processes behind these interactions can be of great use for developing treatments against bacterial diseases. The aim of this thesis project was to verify, and introduce a model for understanding, the i
Streptococcus bovis/Streptococcus equinus complex (SBSEC) is a common cause of infective endocarditis (IE). For IE-pathogens, the capacity to activate and aggregate platelets is believed to be an important virulence mechanism. While the interactions between bacteria and platelets have been described in detail for many Gram-positive pathogens, little research has been carried out with SBSEC in this
While the eddy covariance (EC) technique is a well-established method for measuring water fluxes (i.e., evaporation or 'evapotranspiration’, ET), the measurement is susceptible to many uncertainties. One such issue is the potential underestimation of ET when relative humidity (RH) is high (>70%), due to low-pass filtering with some EC systems. Yet, this underestimation for different types of EC sy
