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Systemic sclerosis. Novel molecular and epidemiological features of disease.

Popular Abstract in Swedish Systemisk skleros (SSc) är en relativt ovanlig reumatologisk sjukdom som kan engagera många av kroppens organ. Sjukdomen kallas ibland också för sklerodermi. Typiskt för sjukdomen är att huden omvandlas till fibros och blir hård och stram över olika delar av kroppen. Typiskt för sjukdomen är också att drabbade patienter har försämrad funktion i sina blodkärl, framförallSystemic sclerosis (SSc) is a systemic rheumatic disease with significant mortality and morbidity. Different estimations of disease prevalence and incidence have been presented from various parts of the world. While lung involvement is a common cause of SSc-related death, a majority of SSc patients suffer from symptoms originating in the gastrointestinal (GI) tract. By combining data from a popu

ICOS-ligand triggering impairs osteoclast differentiation and function in vitro and in vivo

Osteoblasts, osteocytes, and osteoclasts (OCs) are involved in the bone production and resorption, which are crucial in bone homeostasis. OC hyperactivation plays a role in the exaggerated bone resorption of diseases such as osteoporosis, rheumatoid arthritis, and osteolytic tumor metastases. This work stems from the finding that OCs can express B7h (ICOS-Ligand), which is the ligand of the ICOS T

Utvc22 schedule autumn2017 updated 2017-08-10

BIDS UTVC22 Lectures and seminars 2017. Schedule 2017-08-10 Date Time Room Theme Activity Group Teacher Module 1: Course Introduction 1/11 10:15-12:00 111 Course introduction Intro 1/1 AF Issues in contemporary development: The quest for growth and the internationalization of development 3/11 10:15-12:00 111 The Elusive Quest for Growth Lec 1/1 PYA 8/11 10:15-12:00 111 The Elusive Quest for Growth

https://www.keg.lu.se/sites/keg.lu.se/files/utvc22_schedule_autumn2017_updated_2017-08-10.pdf - 2026-05-30

Utvc22 schedule autumn2017 updated 2017-05-12

BIDS UTVC22 Lectures and seminars 2017. Schedule 2017-05-12 Date Time Room Theme Activity Group Teacher Module 1: Course Introduction 1/11 10:15-12:00 111 Course introduction Intro 1/1 AF Issues in contemporary development: The quest for growth and the internationalization of development 3/11 10:15-12:00 111 The Elusive Quest for Growth Lec 1/1 PYA 8/11 10:15-12:00 111 The Elusive Quest for Growth

https://www.keg.lu.se/sites/keg.lu.se/files/utvc22_schedule_autumn2017_updated_2017-05-12.pdf - 2026-05-30

µHDS system for desulfurization of logistic fuels for fuel cell applications

Bränsleceller är ett intressant alternativ till förbränningsmotorer då bränsleceller har en högre effektivitet, är miljövänligare samt tystare. Bränslen som diesel, bensin samt det undersökta bränslet Jet A1, innehåller olika svårreagerade svavelföreningar. Problemet med bränslena är att de har ett relativt högt svavelinnehåll. Svavelföreningarna riskerar att förgifta katalysatorerna i de nedströ

Development and validation of a machine learning-based model to predict isolated post-challenge hyperglycemia in middle-aged and elder adults : Analysis from a multicentric study

Introduction: Due to the high cost and complexity, the oral glucose tolerance test is not adopted as the screening method for identifying diabetes patients, which leads to the misdiagnosis of patients with isolated post-challenge hyperglycemia (IPH), that is., patients with normal fasting plasma glucose (<7.0 mmoL/L) and abnormal 2-h postprandial blood glucose (≥11.1 mmoL/L). We aimed to develop a

Mode of Coreceptor Use by R5 HIV Type 1 Correlates with Disease Stage: A Study of Paired Plasma and Cerebrospinal Fluid Isolates.

Abstract Through the use of chimeric CXCR4/CCR5 receptors we have previously shown that CCR5-tropic (R5) HIV-1 isolates acquire a more flexible receptor use over time, and that this links to a reduced viral susceptibility to inhibition by the CCR5 ligand RANTES. These findings may have relevance with regards to the efficacy of antiretroviral compounds that target CCR5/virus interactions. Compartme