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β-Mannan degradation by gut bacteria - Characterization of β-mannanases from families GH5 and GH26

Popular Abstract in Swedish Människan lever inte bara själv, utan tillsammans med en mängd bakterier som lever i kroppen. Större delen av dessa lever i tjocktarmen. Dessa organismer är viktiga för vår hälsa. De stimulerar immunförsvaret, sänker pH i tarmen och gör det ogynnsamt för sjukdomsframkallande bakterier att växa till. Bakterierna lever i symbios med oss och med varandra. Förändringar i taThe human gut flora is important for our well-being. The gut bacteria are able to degrade and metabolize complex carbohydrates. Examples of such carbohydrates are β-mannans. β-Mannans consist of a backbone of β-1,4-linked mannose units and are present in e.g. the endosperm of legumes such as guar or carob. The composition of the β-mannan varies with the plant source. Carob and guar β-mannans are s

Streptococcus pyogenes secreted enzymes interacting with the human host

Streptococcus pyogenes is one of the most common bacteria infecting humans. One of the factors contributing to the disease-causing properties is the secreted streptococcal cysteine proteinase, SpeB, which degrades several host proteins in connective tissue and circulation. SpeB activity depends on the transformation from an inactive precursor, zymogen, into a mature proteinase. We show that

A framework for inversion of wavefield spectra in seismic non-destructive testing of pavements

A method for the inversion of wavefield spectra in non-destructive testing of pavements is outlined. Data acquisition and processing is based on the Multichannel Analysis of Surface Waves (MASW) method. The inversion of a vertical-shear wave velocity profile is conducted on the full wave field spectrum using the Fast Simulated Annealing (FSA) algorithm. This procedure avoids dealing with discrete

Results of a phase I/II study of ocrelizumab, a fully humanized anti-CD20 mAb, in patients with relapsed/refractory follicular lymphoma

Background: Ocrelizumab is a humanized anti-CD20 antibody with increased antibody-dependent cellular cytotoxicity compared with rituximab. This phase I/II study evaluated its safety and efficacy in patients with relapsed/refractory follicular lymphoma (FL) after prior rituximab therapy. Design and methods: Forty-seven patients were treated in three dose cohorts and received eight infusions every 3

Energy Storage & Conversion

Sustainable energy storage and conversion explores innovative methods to efficiently store and transform energy from various renewable sources. It focuses on technologies like advanced batteries, hydrogen production, fuel cells, and thermochemical systems as well as safety aspects of battery storage systems. Research aims to enhance energy density, reduce costs, and improve scalability, enabling r

https://www.energy.lth.se/research/energy-storage-conversion - 2026-06-05

Reactions between ferric oxyhydroxide mineral coatings and a dimethoxyhydroquinone : A source of hydroxyl radicals

Quinones are organic molecules that facilitate electron-transfer reactions in terrestrial environments. The reduced forms, hydroquinones, are powerful reductants that can trigger non-enzymatic radical-based decomposition of organic matter and contaminants by simultaneous reduction of iron and oxygen. Iron oxides often occur as coatings on other minerals, thus our study investigated the reactions b

Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance

Metabolomic screening of fasting plasma from nondiabetic subjects identified alpha-hydroxybutyrate (alpha-HB) and linoleoyl-glycerophosphocholine (L-GPC) as joint markers of insulin resistance (IR) and glucose intolerance. To test the predictivity of alpha-HB and L-GPC for incident dysglycemia, alpha-HB and L-GPC measurements were obtained in two observational cohorts, comprising 1,261 nondiabetic

Metformin-induced suppression of Nemo-like kinase improves erythropoiesis in preclinical models of Diamond–Blackfan anemia through induction of miR-26a

Diamond–Blackfan anemia (DBA) results from haploinsufficiency of ribosomal protein subunits in hematopoietic progenitors in the earliest stages of committed erythropoiesis. Nemo-like kinase (NLK) is chronically hyperactivated in committed erythroid progenitors and precursors in multiple human and murine models of DBA. Inhibition of NLK activity and suppression of NLK expression both improve erythr

About this site

The Faculty of Science's website is part of Lund University's web and uses the same publishing system. The central web unit is responsible for the system and the technical aspects while the Faculty of Science is responsible for the content. Processing of personal dataLund University processes personal data in accordance with the EU's General Data Protection Regulation (GDPR) 2016/679, the Data Pro

https://www.science.lu.se/internal/about-site - 2026-06-05

About this site

The Faculty of Science's website is part of Lund University's web and uses the same publishing system. The central web unit is responsible for the system and the technical aspects while the Faculty of Science is responsible for the content. Processing of personal dataLund University processes personal data in accordance with the EU's General Data Protection Regulation (GDPR) 2016/679, the Data Pro

https://www.science.lu.se/about-site - 2026-06-05

Text For Course Site English

Applied Statistics III: Regression Analysis 3 credits (half-time) Dates:  November 6 – December 1, 2023 Course content and aim:  The course provides the participants with in-depth knowledge of different methods in regression analysis and how these methods can be applied in medical research. The course consists of the following five themes: · Introduction to theory and methods of regression analysi

https://www.intramed.lu.se/sites/intramed.lu.se/files/2023-05/Text%20for%20course%20site%20English.docx - 2026-06-06

Multistable Fields

September 19th 2015 the exhibition/installation Multistable Fields opened in the atrium of the main building at Lund university. Here’s the synopsis:The main building of Lund University was inaugurated in 1882. In the building conceived by architect Helgo Zettervall the rational quest for knowledge of Academia is enmeshed with a world of mythical symbols. Sphinxes and griffins meet deans and profe