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Exploring Unorthodox Aquaporins : Characterization of NbXIPs & AtNIPs

Popular science summaryWater is very important for life. In order to survive every organism needs to control the amount of water in its cells. One of the main ways the cell regulates its water content is through aquaporins. Aquaporins are membrane proteins that allow water and/or small neutral molecules to enter or exit the cell. Aquaporins form a large family and are present in all life forms, hoAbstractAquaporins are membrane integral proteins that facilitate the transport of waterand/or other small neutral molecules across biological membranes in cells in allforms of life. Among the subfamilies of aquaporins in higher plants, the X IntrinsicProteins (XIPs) are the most recently discovered subfamily and the leastcharacterized. However, the aromatic/arginine (ar/R) selectivity filter and

A preanalytic validation study of automated bone scan index : Effect on accuracy and reproducibility due to the procedural variabilities in bone scan image acquisition

The effect of the procedural variability in image acquisition on the quantitative assessment of bone scan is unknown. Here, we have developed and performed preanalytical studies to assess the impact of the variability in scanning speed and in vendor-specific γ-camera on reproducibility and accuracy of the automated bone scan index (BSI). Methods: Two separate preanalytical studies were performed:

Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest - an analysis of the TTM trial data

Background: Targeted temperature management is recommended after out-of-hospital cardiac arrest and may be achieved using a variety of cooling devices. This study was conducted to explore the performance and outcomes for intravascular versus surface devices for targeted temperature management after out-of-hospital cardiac arrest. Method: A retrospective analysis of data from the Targeted Temperatu

Protonolysis of Dialkyl and Alkylaryl Platinum(II) Complexes and Geometrical Isomerization of the Derived Monoorgano-Solvento Complexes: Clear-Cut Examples of Associative and Dissociative Pathways in Platinum Chemistry

SynopsisProtonolysis of the title compounds involves rate-determining proton transfer to the substrate. Subsequent isomerization is dissociative. Activation volumes for the two processes have opposite signs. A new kinetic β-hydrogen accelerating effect for isomerization favoring the fluxionality of a T-shaped 14-electron intermediate is reported.AbstractAbstract ImageProtonolysis of the complexes SynopsisProtonolysis of the title compounds involves rate-determining proton transfer to the substrate. Subsequent isomerization is dissociative. Activation volumes for the two processes have opposite signs. A new kinetic β-hydrogen accelerating effect for isomerization favoring the fluxionality of a T-shaped 14-electron intermediate is reported.AbstractProtonolysis of the complexes cis-[PtR2(PEt3

Impact of Human Papillomavirus (HPV)-6/11/16/18 Vaccine on All HPV-Associated Genital Diseases in Young Women.

Background The impact of the prophylactic vaccine against human papillomavirus (HPV) types 6, 11, 16, and 18 (HPV6/11/16/18) on all HPV-associated genital disease was investigated in a population that approximates sexually naive women in that they were "negative to 14 HPV types" and in a mixed population of HPV-exposed and -unexposed women (intention-to-treat group). Methods This analysis studied

Assessment of conventional cardiovascular risk factors and multiple biomarkers for the prediction of incident heart failure and atrial fibrillation.

OBJECTIVES: the purpose of this study was to assess the predictive accuracy of conventional cardiovascular risk factors for incident heart failure and atrial fibrillation, and the added benefit of multiple biomarkers reflecting diverse pathophysiological pathways. BACKGROUND: heart failure and atrial fibrillation are interrelated cardiac diseases associated with substantial morbidity and mortality

Thermal insulation of occupational footwear used in Japan

Introduction Many kinds of footwear are used for various purposes in the workplace in Japan. Careful selection of footwear is needed to protect workers from coldness and to keep the performance of workers in cold workplace where employees have to work under -20℃. On the other hand, safety boots with high heat conductivity from foot to outside are needed for the workers in hot environments. But the

In-depth studies on sex trafficking in women: the case of justice response, jurisprudence and human rights in Southeastern Europe

Sex trafficking has from six hundred thousand to four million victims each year (McCabe and Manian, 2010: 41-43). Because of different legal barriers, sex trafficking is closely associated with organized crime; crime victims often do not search for support from legal systems, law enforcement authorities, or other officials (ibid.) This thesis was to understand how law affects the ability of preven

Achievment of sustainable solid waste management in developing countries

With an increasingly population and urbanization, the solid waste management have become a major challenge for local authorities in developing countries all over the world. The local authorities must improve their waste management in order to minimize the negative effects of solid waste and to avoid future land use conflicts. At the same time the economical resources are limited and solid waste ma

Advanced decision support methods for solving diffuse water pollution problems

Dealing with water diffuse pollution is a major problem for watershed managers. This problem raises many complicated questions, which are important to answer in order to reach water environment protection goals. This study suggested some possible answers for the country of Lithuania. Among them were the identification of critical source areas, the identification of sensitive areas and the applicat

Empowerment and enablement and their associations with change in health-related quality of life after a supported osteoarthritis self-management programme - a prospective observational study

BACKGROUND: Osteoarthritis is a leading cause of disability worldwide. Current treatment supports coping strategies to improve health-related quality of life (HRQoL). The need to predict response to treatment has been raised to personalise care. This study aims to examine change in HRQoL from baseline to three and nine months follow-up after participating in a Supported Osteoarthritis Self-Managem

Genetic Moderation of the Association of β-Amyloid With Cognition and MRI Brain Structure in Alzheimer Disease

Background and Objectives: There is considerable heterogeneity in the association between increasing β-amyloid (Aβ) pathology and early cognitive dysfunction in preclinical Alzheimer disease (AD). At this stage, some individuals show no signs of cognitive dysfunction, while others show clear signs of decline. The factors explaining this heterogeneity are particularly important for understanding pr

Kalkylmodeller i affärssystem: Påverkan på varulagervärdering i tillverkande företag

Uppsatsens titel: Kalkylmodeller i affärssystem: Påverkan på varulagervärdering i tillverkande företag. Seminariedatum: 31 maj, 2012 Ämne/Kurs: Examensarbete, Civilekonomprogrammet, inriktning redovisning, 30 HP, uppsats på magisternivå. Författare: Norrlid, Daniel & Åberg, Marcus Handledare: Dergård, Johan & Sandell, Niklas Nyckelord: Affärssystem, produktkalkylering, varulager, varulagerTitle: Costing methods in Enterprise Resource Planning Systems: The effects on inventory valuation in manufacturing companies. Seminar date: May 31, 2012 Course: Master thesis in Business Administration, 30 University Credit Points (30 ECTS) Authors: Norrlid, Daniel & Åberg, Marcus Advisors: Dergård, Johan & Sandell, Niklas Key words: Enterprise Resource Planning Systems, costing methods,

Absorbed dose distributions in the vicinity of high-density materials in head and neck radiotherapy A quantitative comparison between measurements, Monte Carlo simulations and treatment planning system

Varje år diagnostiseras i Sverige ungefär 1100 personer med cancer i huvudhalsregionen. Typiska diagnoser är tungcancer, läppcancer och cancer i struphuvudet. I och runt om munhålan finns det stora skillnader i densitet mellan till exempel vävnad och tänder och vävnad och tandlagningar. I detta arbete så har effekterna av ett antal olika tandlagningsmaterial på dosberäkningarna undersökts. För a"Introduction: Around 1.000 people are diagnosed with head and neck cancer in Sweden every year. Radiotherapy is often used to treat these tumors. When irradiating patients in the head and neck area there are some problems. One of these problems is the large difference in density between the oral tissue and dental materials. Another problem is the image artifacts due to high-density materials

Changes in the concentrations of major, minor and rare-earth elements during leaf senescence and decomposition in a Fagus sylvatica forest

The principal fate during litter decomposition and mineralization is rather well established only for a limited number of elements, mainly essential plant nutrients and a few potentially very toxic metals. Elements which occupy the majority of the positions in the periodical system seems almost unknown in this context. The objectives were, therefore to assess differences in the behavior of 58 mine

Total parenteral nutrition modulates hormone release by stimulating expression and activity of inducible nitric oxide synthase in rat pancreatic islets

The expression and activities of constitutive nitric oxide synthase (cNOS) and inducible nitric oxide synthase (iNOS) in relation to insulin and glucagon secretory mechanisms were investigated in islets isolated from rats subjected to total parenteral nutrition (TPN) for 10 d. TPN is known to result in significantly increased levels of plasma lipids during the infusion time. In comparison with isl

Erythema Migrans in Primary Health Care

Lyme borreliosis (LB) is the most common vector-borne disease in the northern hemisphere, and southern Sweden is a highly endemic area. In over 70% of the cases, LB is represented by the non-disseminated cutaneous form erythema migrans (EM). This thesis has its focus on EM from a primary health care perspective in southern Sweden, including aspects on epidemiology, the clinical picture, gender dif

When the refusal to deal becomes an abuse of a dominant position - A study of how article 82 EC Treaty limits the freedom of action for undertakings in a dominant position

In my paper I have emanated from the question when a refusal to deal by an undertaking in a dominant position constitutes an abuse according to article 82 EC Treaty. Article 82 of The Consolidated version of the Treaty establishing the European Community, signed in Rome 1957, incorporating the changes made by the Treaty of Amsterdam on 2 October 1997, OJ 1997 C340, pp. 173-308, hereafter referred

Characterization of male breast cancer : Results of the EORTC 10085/TBCRC/BIG/NABCG International Male Breast Cancer Program

Background: Male breast cancer (BC) is rare, managed by extrapolation from female BC. The International Male BC Program aims to better characterize and manage this disease. We report the results of part I, a retrospective joint analysis of cases diagnosed during a 20-year period. Methods: Patients with follow-up and tumor samples, treated between 1990 and 2010, in 93 centers/9 countries. Samples w