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Deposition of phosphorus (P) is important for the nutrient supply to forests and open land but also contributes to the eutrophication of surface waters. Deposition to open land can be measured as bulk deposition while deposition to forests cannot be measured directly, due to internal circulation of P within forest canopies. This study aimed to quantify the total deposition of P to open land and fo
In situ synthesis of oestrogens is of great importance in the development and progression of breast cancer. 17β-hydroxysteroid dehydrogenase (17HSD) type 2 catalyses oxidation from oestradiol to oestrone, and thereby protects the breast epithelial cells from oestradiol. Low expression of 17HSD type 2 has been associated with decreased survival in breast cancer, but no studies have investigated the
Temporal information in episodic memory reflects how experiences are encoded rather than objective elapsed time, giving rise to systematic distortions. These are particularly evident in emotional contexts, consistent with emotion-related biases in attention. The present study investigated whether emotion-driven distortions in remembered temporal distance were explained by encoding-related attentio
Streptomycetes grow as filamentous cells called hyphae. These cells elongate using a polar method of growth where the cell wall synthesis is restricted to the hyphal tips. It has been proved that the protein DivIVA directs the cell wall assembly to the poles and initiate branch formation along the lateral cell wall. Observations of DivIVA shows that it is regulated by AfsK, a Ser/Thr protein kinas
The digital platform Airbnb has gained popularity in a number of countries particu- larly in the Maltese islands. Striking a balance in setting a price that is competitive and also renders a good profit can be a challenge. In this thesis a model is de- veloped to predict the price of a listing in the Maltese islands for September 2022 through a machine learning approach whereby five types of model
Wildfires causes natural disturbances to ecosystems which can have potentially damaging results for ecosystem services and economic income from timber production. The post-fire management approach can be essential for the environmental work regarding the recovery of ecosystems and maintaining ecosystem services. The aim of this study was therefore to evaluate different post-fire management approac
With warming in soils due to climate change, a series of secondary factors arise, which have multifaceted effects on soil microbial communities. Of these, alterations to soil moisture are among the most crucial to understanding how microbial functions will change in the face of climate change. As living organisms, microbes must adapt to their environment, and their adaptations are reflected in the
Denna studie är en fallstudie av en byggnad belägen i Malmö, Sverige, som undersöker olika energieffektiva åtgärder och deras potentiella påverkan på byggnadens energikonsumtion. En förstudie genomfördes för att inhämta kunskap om tillämpliga energieffektiva åtgärder från befintlig forskning. Därefter genomfördes fallstudien i tre huvudsakliga faser. I den första fasen samlades byggnadsinformationThis study is a single case study of a building situated in Malmö, Sweden, examining various retrofit measures and their potential impact on the building’s energy performance. A pre-study was carried out to gain knowledge on applicable retrofitting measures from existing literature. Subsequently, the case study consisted of three major phases. In the first phase, building information was collected
Reverse Supply Chain (RSC) is defined as the value chain for defect products returning to the company, or its partners, from customers, or the end users. The defect products are thereafter either disposed & replaced, or repaired & reused. Axis communications have an established RSC department, which would like to deepen their knowledge how certain product- and production parameters can be
Exposed, well-drained and nutrient poor areas on Spitsbergen are mainly covered by a plant alliance typical for Svalbard, the Caricion nardinae. Caricion nardinae is a circum-polar alliance, which is dominated by the creeping, ever-green dwarf-shrub Dryas octopetala. On the beach flats of western Spitsbergen, Jonas Åkerman (1983) observed in 1979 the plant Dryas octopetala growing in an unusual pa
Objective: Dose optimization and pharmacokinetic evaluation of α-particle emitting radium-223 dichloride (223RaCl2) by planar γ-camera or single photon emission computed tomography (SPECT) imaging are hampered by the low photon abundance and injected activities. In this study, we demonstrate SPECT of 223Ra using phantoms and small animal in vivo models. Methods: Line phantoms and mice bearing 223R
In situ remediation of contaminated groundwater often relies on the installation of a treatment zone (TZ) degrading the contamination. Zero-valent-iron (ZVI) is a type of reagent used for this purpose. Adequate delivery of ZVI in the whole target volume is particularly challenging and requires monitoring with high spatial resolution. We present a monitoring tool for imaging the dynamic spreading o
Achieving CRISPR Cas9-based manipulation of mitochondrial DNA (mtDNA) has been a long-standing goal and would be of great relevance for disease modeling and for clinical applications. In this project, we aimed to deliver Cas9 into the mitochondria of human cells and analyzed Cas9-induced mtDNA cleavage and measured the resulting mtDNA depletion with multiplexed qPCR. In initial experiments, we fou
Since the early 1990s, many variants of the tPSA assay have been introduced to increase the sensitivity of screening programs (cancer detection) while maintaining specificity (elimination of unnecessary biopsies). Again, these guidelines recommend ways that individuals and their physicians can use these new techniques rationally for early detection of prostate cancer. These guidelines are not desi
Objectives. The subcellular localization of the breast cancer susceptibility gene product BRCA1 has been controversial. Discrepant results have been reported during the past 3 years, partially because of the unavailability of highly specific reagents for BRCA1 protein. Our objective was to characterize the BRCA1-like immunoreactivity that is detected in human seminal plasma by using monoclonal and
Diachronic and synchronic studies of linguistic landscapes of central streets and markets were conducted in five cities in Ukraine with different language use preferences in 2015 and 2017–19. The relationship between a monolingual state language policy and the reality of language use in public spaces was investigated. This study focuses on the dynamics of the linguistic landscape of Odesa, a Russi
Background: Gallbladder cancer (GBC) is an aggressive, uncommon malignancy, with variation in operative approaches adopted across centres and few large-scale studies to guide practice. We aimed to identify the extent of heterogeneity in GBC internationally to better inform the need for future multicentre studies. Methods: A 34-question online survey was disseminated to members of the European-Afri
Objective: Characterise the spatiotemporal trabecular and cortical bone responses to complete spinal cord injury (SCI) in young rats. Methods: 8-week-old male Wistar rats received T9-transection SCI and were euthanised 2-, 6-, 10-or 16-weeks post-surgery. Outcome measures were assessed using micro-computed tomography, mechanical testing, serum markers and Fourier-transform infrared spectroscopy. R
Ice-core timescales are vital for the understanding of past climate; hence they should be updated whenever significant amounts of new data become available. Here, the Greenland ice-core chronology GICC05 was revised for the last 3835 years by synchronizing six deep ice cores and three shallow ice cores from the central Greenland ice sheet. A new method was applied by combining automated counting o
New antimicrobial agents are needed to address the ever-growing risk of bacterial resistance, particularly for methicillin- and vancomycin-resistant Staphylococcus aureus (S. aureus). Here, we report a class of bile acid oligomers as facial amphiphilic antimicrobials, which are noncovalently fabricated by cholic acid (CA) and deoxycholic acid (DCA) with polyamines (e.g., diamines, diethylenetriami
