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The aim of this study was to develop (68)Ga-SPIONs for use as a single contrast agent for dynamic, quantitative and high resolution PET/MR imaging of Sentinel Lymph Node (SLN). In addition (68)Ga enables Cherenkov light emission which can be used for optical guidance during resection of SLN. SPIONs were labeled with (68)Ga in ammonium acetate buffer, pH 5.5. The labeling yield and stability in hum

The central nervous system (CNS) monitors modifications in metabolic parameters or hormone levels and elicits adaptive responses such as food intake regulation. Particularly, within the hypothalamus, leptin modulates the activity of pro-opiomelanocortin (POMC) neurons which are critical regulators of energy balance. Consistent with a pivotal role of the melanocortin system in the control of energy

Tre borrkärnor bestående av sjösediment, vardera 1.5 meter långa, från Byestadsjön i Småland, Sverige studerades med hjälp av mineralmagnetiska- kol- pollen- och röntgenflourosens (XRF)- analyser. Målet med studien var att rekonstruera tidig Holocen miljö, med fokus på tiden mellan 9000-7000 år sedan och därmed avgöra om det kalla klimatåterslaget cirka 8200 före nutid påverkade regionen eller ej.Three sediment cores, each 1.5 meters in length, obtained from Lake Byestadsjön in the province of Småland, southern Sweden were studied with high resolution mineral magnetic measurements, carbon content, pollen analysis and XRF analysis. The aim was to reconstruct the early Holocene environment, with focus on the period between 9000-7000 cal yr BP, and thereby conclude if the 8200 cal yr BP cooli

A personal transporter is under development at LTH, Industrial Electrical Engineering and Automation, IEA. A wireless link is desired to develop control remotely for the transporter. The development of the control becomes easier without wires and if the transporter can move freely within the range of the link. A link is built, using Bluetooth devices and a microprocessor from Microchip. This link

Depth data and bathymetry maps are used to analyze their association with tides, winds, currents and wave conditions in the port of Talara, at the coast of northern Peru. The objective is to investigate the processes that influence the sediment transport in the port. The sedimentation affects the saltwater pumps for fire fighting, obstructing them from delivering water since their operational wate

Myrosinase from Sinapis alba hydrolyzes glycosidic bonds of β-d-S-glucosides. The enzyme shows an enhanced activity in the presence of l-ascorbic acid. In this work, we employed combined quantum mechanical and molecular mechanical (QM/MM) calculations and molecular dynamics simulations to study the catalytic reaction of wild-type myrosinase and its E464A, Q187A, and Q187E mutants. Test calculation

Background: Transrectal prostate biopsy (TRbx) transfers colonic bacteria into prostatic tissue, potentially causing infectious complications, including sepsis. Our objective was to determine whether biopsy needle shape, surface properties and sampling mechanism affect the number of bacteria transferred through the colon wall, and evaluate a novel needle with improved properties. Methods: The stan

Recent outlooks suggest a long-term relevance of internal combustion engines for both power generation and transportation. Nonetheless, stringent pollutant reduction requirements combined with new CO2 mandates draws a challenging scenario, requiring intensive research and development activities to develop and optimize combustion modes to fulfill these requirements. Among the recent advancements, t

Avian communities play a pivotal role in Arctic ecosystems and birds have become the key model taxa for climate change research. Due to funding priorities, Arctic passerines have been studied less intensively than waterfowl and shorebirds. In our study, we aim to partly fill this gap and look at the change in passerine community species composition in the Chaun River Delta in Northeast Siberia (68

OBJECTIVE: The aim of the present study was to examine the effects of incomplete surgery and adjuvant chemotherapy on the prognosis of patients with intraoperative rupture of capsulated stage I epithelial ovarian cancer (OvCa). METHODS: A regional retrospective study was conducted between 1986 and 2019. Among 4,730 patients with malignant ovarian tumors, 534 women with International Federation of

Predation risk is often invoked to explain variation in stress responses. Yet, the answers to several key questions remain elusive, including the following: (1) how predation risk influences the evolution of stress phenotypes, (2) the relative importance of environmental versus genetic factors in stress reactivity and (3) sexual dimorphism in stress physiology. To address these questions, we explo

Thousands of species migrate [1]. Though we have some understanding of where and when they travel, we still have very little insight into who migrates with whom and for how long. Group formation is pivotal in allowing individuals to interact, transfer information, and adapt to changing conditions [2]. Yet it is remarkably difficult to infer group membership in migrating animals without being able

The measurement of innovation is a challenging task for management accounting practitioners and researchers alike. To tackle this task, key performance indicators (KPIs) can be used to measure and follow up innovation. This case study shows how KPIs are used to measure innovation after strategic changes due to competitive pressures. The findings of this study indicate that KPIs in innovation are uMeasuring innovation is a challenging but essential task to improve business performance. To tackle this task, key performance indicators (KPIs) can be used to measure and monitor innovation. The objective of this study is to explore how KPIs, designed for measuring innovation, are used in practice. To achieve this objective, the author draws upon literature on business performance in accounting a