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Cancer incidence, mortality, and survival in Eastern Libya : updated report from the Benghazi Cancer Registry

PURPOSE: Despite the increasing burden of cancer occurred over recent years in the African continent, epidemiologic data from Northern Africa area have been so far sparse or absent. We present most recently available data from the Benghazi Cancer Registry concerning cancer incidence and mortality as well as the most comprehensive survival data set so far generated for cases diagnosed during 2003 t

Understanding the complex metallic element Mn. I. Crystalline and noncollinear magnetic structure of α−Mn

Manganese is an element with outstanding structural and magnetic properties. While most metallic elements adopt a simple crystal structure and order magnetically—if at all—in a simple ferromagnetic or antiferromagnetic configuration, the stable phase of manganese at ambient conditions, paramagnetic α−Mn, adopts a complex crystal structure with 58 atoms in the cubic cell. At a Néel temperature of T

Exploring Design Potentials in Porous Urban Space : Split Vision Urbanism HK through Montage

Split Vision Urbanism HK is a design research project located at the intersection of urban governance, architectural design, and media arts. It seeks to critically address the relationship between formal and informal structures in order to uncover the hidden potentials of porous urban space, extracting new territories for design practices to engage the generative aspects of high density. Drawing o

Målinriktad informationssökning till olika besökargrupper i Helsingborg : Slutrapport

Rapporten belyser resultaten från ett Plattformsfinansierat projekt som löpt från 2018 till 2019 med syfte att undersöka dels olika besökares informationsbeteende i Helsingborg, dels vilket värde besökarna tillskriver de olika informationskanalerna. Frågan är hur vi kan förstå besökarna i ett allt mer digitalt sammanhang. Vilka informationskanaler är intressanta för besökarna och vilket värde till

A-uppsats eller kritisk essä - är det frågan?

Vilka former och uttryck kan en avslutande skriftlig uppgift på grundkursen ta? För att initiera en diskussion som tar vara på den samlade expertis och erfarenhet som finns bland åhörarna ställer jag frågan: hur skapar vi som lärare progression och konstruktiv länkning från första större skrivuppgift till en väntande kandidatuppsats? Syftet med presentationen är att öppna för denna diskussion om h

Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling

The activity-regulated cytoskeleton-associated (Arc) protein is essential for synaptic plasticity and memory formation. The Arc gene, which contains remnants of a structural GAG retrotransposon sequence, produces a protein that self-assembles into capsid-like structures harboring Arc mRNA. Arc capsids, released from neurons, have been proposed as a novel intercellular mechanism for mRNA transmissi

Histopathological dimensions differ between aganglionic and ganglionic bowel wall in children with Hirschsprung’s disease

Background: In the validation of new imaging technology for children with Hirschsprung’s disease (HSCR), basic anatomical parameters of the bowel wall must be established specifically for this patient group. Aim: To explore differences in histoanatomical layers of bowel wall, comparing ganglionic and aganglionic bowel walls, and to examine if the bowel wall thickness is linked to patient weight. M

Asymmetric changes in temperature in the Arctic during the Holocene based on a transient run with the Community Earth System Model (CESM)

The Arctic temperature changes are closely linked to midlatitude weather variability and extreme events, which has attracted much attention in recent decades. Syntheses of proxy data from poleward of 60g gN indicate that there was asymmetric cooling of-1.54 and-0.61gg C for the Atlantic Arctic and the Pacific Arctic during the Holocene, respectively. We also present a similar consistent cooling pa

Hydroxyapatite : An Antibiotic Recruiting Moiety for Local Treatment and Prevention of Bone Infections

Treatment of chronic osteomyelitis by radical debridement and filling of the dead space with antibiotic containing calcium sulphate/hydroxyapatite (CaS/HA) bone substitute has shown excellent long-term outcomes. However, in extensive infections, sessile bacteria may remain in bone cells or soft tissues protected by biofilm leading to recurrences. The primary aim of this study was to evaluate if sy

The generalisability of randomised clinical trials : an interim external validity analysis of the ongoing SENOMAC trial in sentinel lymph node-positive breast cancer

Purpose: None of the key randomised trials on the omission of axillary lymph node dissection (ALND) in sentinel lymph-positive breast cancer have reported external validity, even though results indicate selection bias. Our aim was to assess the external validity of the ongoing randomised SENOMAC trial by comparing characteristics of Swedish SENOMAC trial participants with non-included eligible pat

Usability of mepolizumab single-use prefilled syringe for patient self-administration

Objective: A liquid mepolizumab formulation in a single-use prefilled syringe (PFS) is under development. We evaluated the usability of mepolizumab self-injected via PFS by patients with severe eosinophilic asthma (SEA), or their caregivers, in clinic and at home. Methods: This open-label, single-arm, Phase IIIa study included patients with SEA, aged ≥12 years, and receiving mepolizumab (100 mg su

May Measurement Month 2018 : a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension

AIMS: Raised blood pressure (BP) is the biggest contributor to mortality and disease burden worldwide and fewer than half of those with hypertension are aware of it. May Measurement Month (MMM) is a global campaign set up in 2017, to raise awareness of high BP and as a pragmatic solution to a lack of formal screening worldwide. The 2018 campaign was expanded, aiming to include more participants an

Atrophic Myenteric and Submucosal Neurons Are Observed in Parkinson's Disease

Aim. Parkinson's disease is often accompanied by gastrointestinal symptoms, especially constipation. Microscopic studies of the enteric nervous system and enteric neuropathy have often been performed by immunostaining in the myenteric plexa. The aim of the present study was to examine whether pathologic changes could be identified by conventional hematoxylin and eosin (H&E) staining and could

Cytogenetic studies in non‐Hodgkin lymphomas ‐ Results from surgical biopsies

Cytogenetic analysis using Giemsa banding technique was successful in 30 of the 49 adult patients with nonHodgkin lymphomas investigated. The results are correlated with previous findings in 48 non‐Hodgkin lymphoma patients studied by means of fine needle aspiration in our laboratory. As 8 patients were included in both series, the total number successfully investigated was 70. The success rate wi

Open source ERP business model framework

ERP systems became popular with large organizations in the 1990s. In the 21st Century, these products were expanded by addition of supply chain management (SCM) and customer relationship management (CRM), as well as access through the Web, creating the ERP II concept. Efforts to increase the market led vendors to serve not only large organizations, but also focus more on small-to-medium sized ente

Stratigraphy and geothermal assessment of Mesozoic sandstone reservoirs in the Öresund Basin - exemplified by well data and seismic profiles

The Øresund Basin in the transnational area between Sweden and Denmark forms a marginal part of the Danish Basin. The structural outline and stratigraphy of the Mesozoic succession is described, and a novel interpretation and description of the subsurface geology and geothermal potential in the North Sjælland Half-graben is presented. The subsurface bedrock in the basin includes several Mesozoic i

Characterization of Patients with Embolic Strokes of Undetermined Source in the NAVIGATE ESUS Randomized Trial

Background: The New Approach Rivaroxaban Inhibition of Factor Xa in a Global Trial vs. ASA to Prevent Embolism in Embolic Stroke of Undetermined Source (NAVIGATE-ESUS) trial is a randomized phase-III trial comparing rivaroxaban versus aspirin in patients with recent ESUS. Aims: We aimed to describe the baseline characteristics of this large ESUS cohort to explore relationships among key subgroups.