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Assembly of protein S and C4b-binding protein on membranes

The interaction of protein S with membranes and subsequent combination with complement C4b-binding protein (C4BP) was studied. Protein S interacted with phospholipid vesicles in a calcium-dependent manner typical of other vitamin K-dependent proteins. Association of C4BP with protein S showed no apparent selectivity for membrane-bound or solution phase protein S. When bound to the membrane, the pr

How do clinical supervisors and managers in Swedish primary care perceive their opportunities to meet the learning needs of medical students?

Introduction: Primary health care centers (PHCCs) in Sweden are struggling to maintain a balance between increasing demands of service and supervision and learning activities for a growing number of students. We sought a deeper understanding of primary care physicians and managers behavioral intention towards supervising, and their perceptions of the structural preconditions and support needed.Met

Experience of a systematic approach to care and prevention of fragility fractures in New Zealand

Summary: This narrative review describes efforts to improve the care and prevention of fragility fractures in New Zealand from 2012 to 2022. This includes development of clinical standards and registries to benchmark provision of care, and public awareness campaigns to promote a life-course approach to bone health. Purpose: This review describes the development and implementation of a systematic a

Multi-ancestry genome-wide association study of gestational diabetes mellitus highlights genetic links with type 2 diabetes

Gestational diabetes mellitus (GDM) is associated with increased risk of pregnancy complications and adverse perinatal outcomes. GDM often reoccurs and is associated with increased risk of subsequent diagnosis of type 2 diabetes (T2D). To improve our understanding of the aetiological factors and molecular processes driving the occurrence of GDM, including the extent to which these overlap with T2D

Quantitative evaluation of the tibiofemoral joint cartilage by T2 mapping in patients with acute anterior cruciate ligament injury vs contralateral knees : results from the subacute phase using data from the NACOX study cohort

Objective: Immediate cartilage structural alterations in the acute phase after an anterior cruciate ligament (ACL) rupture may be a precursor to posttraumatic osteoarthritis (PTOA) development. Our aim was to describe changes in cartilage matrix in the subacute phase of the acutely ACL-injured knee compared to the contralateral uninjured knee. Design: Participants (n = 118) aged 15–40 years with a

Extrapancreatic infections are common in acute pancreatitis and they are related to organ failure : a population-based study

BACKGROUND: Although the impact of pancreatic infections in acute pancreatitis has been studied extensively, there are no population-based data on extrapancreatic infections and their potential relation to organ failure. We aimed to study the occurrence of pancreatic and extrapancreatic bacterial infections in acute pancreatitis and their relation to patient outcome. PATIENTS AND METHODS: All pati

Prevalence and genetic diversity of avian haemosporidian parasites at an intersection point of bird migration routes : Sultan Marshes National Park, Turkey

Avian haemosporidians (Haemosporida) represent a globally distributed, species-rich multiparasite-multihost host-parasite system. Each year, many of these parasite lineages are carried between temperate and tropical regions by migratory birds. While several factors can limit the transmission of avian haemosporidians to new areas, recent studies have shown that some abundant parasites can sometimes

The oesophageal route in clinical electrocardiology

The subject of this thesis is the clinical use of the oesophageal electrode in electrocardiology. The three areas covered are oesophageal electro- cardiography, the biophysics of transoesophageal atrial stimulation (TAS) and the clinical utility of TAS. The literature is reviewed with respect to these areas. TAS was performed in 64 patients with documented supraventricular tachycardia (SVT) or a

Laminins and Fibulins in Bone Marrow

Popular Abstract in Swedish Utveckling av blodbildande celler sker i benmärgens mikromiljö, som består av cytokiner och tillväxtfaktorer, stromaceller samt extracellulära matrixmolekyler. Extracellulära matrixproteiner och stromaceller i benmärgen utgör en strukturell miljö för hematopoietiska celler, men adhesiva cell-cell och cell-matrix interaktioner påverkar också direkt hematopoietiska cellerDevelopment of hematopoietic cells in bone marrow takes place in association with the hematopoietic microenvironment. Extracellular matrix (ECM) molecules and stromal cells in bone marrow provide a structural environment for hematopoietic cells, but they also directly influence proliferation, differentiation and migration of cells by signal transduction mediated by ligand binding to cell surface a

Logotyper som informationsbärare : en studie i SVT:s logotyper & Arla Foods logotyper

PROBLEM: Logotyper har en väldigt betydelsefull roll i företaget och är inte bara en utsmyckning för företaget. Logotypen måste passa ihop med företaget och genom logotypen ska företaget föra ut ett budskap om företagets intentioner och ambitioner. Det finns en risk att de kärnvärde som företaget vill förknippas med försvinner vid en logotypförändring eller att företaget på något annat sätt mister

Dramapedagogik: en metod för utveckling i arbetslivet

Bakgrund: Bakgrunden till uppsatsen är de ökade diskussionerna om krav på kommunikativa färdigheter och social kompetens. Arbetslivets behov av att ge personal fullgod utbildning inom dessa områden har därmed hamnat i centrum i dessa diskussioner. Detta ledde till att vi började fundera över olika utvecklingsmetoder att träna sådana förmågor och huruvida man använder sig av pedagogiskt drama för a

Outsourcing. Personalens upplevelser av förändringar

Vi har i vårt arbete utgått från huvudfrågeställningen ”hur upplever personalen förändringar som uppstår i samband med outsourcing?”. Denna frågeställning har vi delat in i följande tre delfrågor som vi anser är centrala för hur personalen upplever förändringarna: Hur upplevde personalen den information som gavs i samband med outsourcingen, hur upplever personalen sina nya roller samt hur upplever

Consumers' behaviour in the use of online services and the cultures effect on it-a study of Swedes and Danes use of online job databases

The thesis deals with consumers behaviour in the use of online services and the cultures effect on it. It is a study of Swedes and Danes use of online job data bases. The thesis is based on a quantitative study. A questionnaire were used sent out to 80 Swedes and 80 Danes. The theory concerns areas of online consumer behaviour, decision making and services theory as well as theories within culture

Organisationskultur och ledarskap - En kvalitativ studie om IKEA Älmhult

Organisationskultur har under senare decennierna blivit ett välkänt och välstuderat fenomen. IKEA är ett företag som har expanderat i snabb takt och företaget bör räknas som synnerligen framgångsrikt. Att som en multinationell koncern välja att behålla kärnverksamheten i en liten by som Älmhult är tämligen unikt, och gör studieobjektet än mer intressant. Av intresse i denna studie är framför allt

OECD:s och EU-rättens inverkan på svensk beskattning av personaloptioner vid utflyttning

On January the first 2009 the rule of exit taxation for stock-options was abolished in favor of a rule adapted to EU case law. The rule of exit taxation regulated employees who participated in stock option plans and who moved out of Sweden before those plans had expired. The rule of exit taxation was aimed at those stock options for which vesting had occurred during the period when the employee r

Sverige, Dublinreglerna och den asylsökandes rättigheter

The first Dublin Regulation was a result of those institutional changes that followed by the Amsterdam Treaty coming into force. The establishment was also a result of the European Council’s conclusions, from their meeting in Tampere in 1999. During the meeting The Council agreed to create a common European asylum system. The Dublin Regulation entered into force in 2003. The purpose of the regul

En två eller flera vårdnadshavare - en komparation av svensk och engelsk rätt

En familj har traditionellt sett bestått av en moder, en fader och ett antal barn. Det innebär att lagstiftningen inom familjerätten är utformad för att passa dessa omständigheter. Lagstiftarna har arbetat utifrån antagandet att de familjer som skulle påverkas av deras lagstiftning skulle vara av den traditionella sorten och att deras lagstiftning därför skulle vara fullt tillräcklig. Det har sagTraditionally families have been made up of a mother, a father and any number of children. This means that the legislation in this area has been made to fit those circumstances. The legislators have worked under the assumption that the families affected by their policies would be of the traditional kind and therefore their policies would be sufficient. It has been said that the legislation in a

Regler i ABL för att styra den aktiebolagsrättsliga firmateckningsrätten. En analys för aktieägare i fåmansaktiebolag

In this essay, the reader receives a presentation of the legal tools, which shareholders in closely held companies could use to ensure that the company is represented according to the rules of the Swedish Company Act. The author, has through its interest in entrepreneurship, small business and start-up ventures wanted to focus on how the shareholders of such closely held companies may use company

Sekundärförpackningens ur butiksperspektiv - En fallstudie med Lantmännen

Det här arbetet har genomförts med hjälp av metoden för en fallstudie med flerfallsdesign och en analysenhet. Svenska livsmedelsbutiker är kontexten i arbetet, fallet är sekundärförpackningar för en viss produktkategori och analysenheten är egenskaper hos sekundärförpackningen. Med sekundärförpackning menas den förpackning som fraktas till butik och innehåller flera konsumentförpackningar, oftast