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Popular Abstract in Swedish Hemofili A är en form av blödarsjuka som beror på en medfödd defekt av äggviteämnet faktor VIII (FVIII). FVIII spelar en viktig roll för att kroppens blodlevringsförmåga (s.k. koagulation) ska fungera optimalt och med nedsatt funktion hos FVIII riskerar man att drabbas av allvarliga blödningar i framför allt leder, men även i muskler, slemhinnor (t.ex. näsblödning) och

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Popular Abstract in Swedish Förekomsten av hudcancer ökar i ljushyade befolkningsgrupper och hudcancer tillhör de cancergrupper som ökar mest i Sverige. De tre vanligaste formerna av hudcancer är basalcellscancer, skivepitelcancer och malignt melanom. Under 2013 utgjorde skivepitelcancer och malignt melanom ca 16 % av alla cancerfall som rapporterades in till Svenska Cancerregistret; över 6 000 faSkin cancer incidence is increasing in fair-skinned populations. The three most common skin cancers are basal cell carcinoma (BCC), squamous cell carcinoma (SCC) and malignant melanoma (MM). A correct diagnosis is crucial for an efficient and tailored treatment for the skin cancer patient. The purpose of this thesis was to evaluate different aspects of the preoperative diagnosis of skin cancer. Th

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Critics maintain that there are a number of troublesome issues resulting from the construction sector’s way of operating and that these remain, despite widespread criticism and measures designed to change all of this. The construction sector’s and the critics’ manner of describing these problems fails to a large extent to take into consideration the way people function in connection with practical

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The main objective of this thesis was to quantitatively estimate the gaseous exchange of carbon dioxide (CO2) and methane (CH4) between a subarctic wetland ecosystem and the atmosphere. Additionally some initial estimates of the carbon input to the atmosphere of nonmethane hydrocarbons (NMHCs) were also obtained by combining different techniques in a joint setting. The data presented were collecte

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Interactions between metals and natural organic matter (NOM) are of great environmental importance and one of the key factors influencing hydrolysis, solubility, and speciation of the metals. However, studying geochemically relevant metals like Al, Fe, and Cu is sometimes associated with analytical problems; for example Fe and Cu are both redox active. Gallium (Ga) is a non-redox active metal that

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In this work conformational studies have been performed on peptides from four different systems in an attempt to gain knowledge about their biological function. Circular dichroism (CD) spectroscopy and nuclear magnetic resonance (NMR) spectroscopy in combination with distance geometry and restrained molecular dynamics simulations were the methods used. A detailed conformational study of a cyclic p

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The small heat shock proteins (sHsps) are a widespread class of molecular chaperones existing in all organisms. During heat stress the sHsps protect other proteins from unfolding and aggregation. In plants the sHsps play an especially prominent part of the stress response. In this thesis chemical crosslinking and mass spectrometric mapping of crosslinked peptides has been used to investigate the

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Vehicle design is characterized by a high number of compromises. The special role of human factors in the process is to ensure that the compromises do not occur at the expense of the driver and passengers. Within the automotive industry there is a need for the development of inexpensive and efficient ergonomic tools, facilitating a fast and cost effective car development process as well as discuss

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Glucose-evoked insulin secretion exhibits two phases: The first phase represents exocytosis of insulin granules situated at the plasma membrane, whereas the second phase reflects insulin release from granules continuously recruited to the plasma membrane. This thesis investigates different aspects of phasic insulin secretion, with the specific aims to elucidate the possible contribution of insulin

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This report is about the housing situation in Manila, capital of the Philippines. 25% of the inhabitants in this mega city live in informal settlements, often on places unsuitable for living. The target area of this paper is Baseco, a large slum area near the outlet of Pasig River and home to 47 000 people according to the 2002 census. Among its many problems including overpopulation and poverty i

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The Internet has revolutionised the global market place. Internet shopping is now accessible to an increasing numbers of people. In theory, this new form of media offers convenience, speed and choice to the consumer, but the question is whether it works in practice? Business-to-consumer cross-border transactions, whether carried out electronically or otherwise, are subject to the existing framewor

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In our society, digital cameras are used for a countless number of different purposes. There are many components going in to making such a complex product but one could argue that the camera sensor and lens make out the heart of a digital camera. Axis Communications AB, founded in 1984, is a Swedish company which pioneered and specialize in digital network cameras. In 1996 Axis delivered the first

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This master’s thesis focuses on pedagogy and aspects of learning and remembering within guided museum tours for people with dementia. We explore in what way learning and remembering are focused on and triggered during those tours and with the help of which pedagogical means. Furthermore, we discuss what place these tours have within the museum as an institution. In order to examine our questions a

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This thesis analyses web statistics belonging to a national B2C e-commerce in retail. The purpose of the thesis is to investigate abandoned carts amongst logged in customers with at least one product added in to their cart and at least one visit to the payment page. Since the response variable "cart" is binary and we are studying the probability of a cart being abandoned, the suitable me

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Punktlighet och förseningar inom järnväg är något som står högt upp på agendan i dagens samhälle. Med en infrastruktur som är i ett stort behov av underhåll samtidigt som trycket på klimatsmarta transportlösningar bara ökar, blir punktligheten och framkomligheten inom järnvägen avgörande. Med en total punktlighet på ungefär 90% finns det mycket att göra. En av järnvägens infrastrukturproblem är spPunctuality and delays within the railway system are of utmost concern in today’s society. With an infrastructure in a dire need of maintenance and the increasing pressure for environmentally friendly transportation solutions, punctuality and accessibility within the railway system becomes crucial. With an overall punctuality rate of approximately 90%, there is much to be improved. One of the prob

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The fact that solitary migratory birds can find their migration routes has indicated the possibility that a genetic basis may be involved in determining the route of migration. Researchers have also found evidence to investigate this hypothesis in various ways. The focal species of this study is the willow warbler (Phylloscopus trochilus), which has three described subspecies (trochilus, acredula

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Denna studie presenterar en detaljerad undersökning av utvecklingen av sedimentära landformer under en ablationssäsong vid Blåisen, en del av Hardangerjøkulen, Norge. Två besök vid Blåisen, i början och i slutet av ablationssäsongen, gjorde det möjligt att studera hur landformerna bevaras och utvecklas. Det pågår mycket forskning om glaciala landformer som är en nyckel till förståelse av hur tidigThis study presents a detailed investigation into the evolution of sedimentary landforms over an ablation season at Blåisen, an outlet of the Hardangerjøkulen Icecap, Norway. The two visits to Blåisen, one each side of the ablation season, allowed the preservation and evolution of the landforms to be studied. Much research is conducted studying glacial landforms, which are key in our understanding