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The GHG-CCI project is one of several projects of the European Space Agency's (ESA) Climate Change Initiative (CCI). The goal of the CCI is to generate and deliver data sets of various satellite-derived Essential Climate Variables (ECVs) in line with GCOS (Global Climate Observing System) requirements. The "ECV Greenhouse Gases" (ECV GHG) is the global distribution of important climate relevant ga
Coastal flooding and erosion are worldwide problems that are further aggravated by rising sea levels and increasing population densities in coastal areas. In many of those areas, sandy beaches and dunes protect thehinterland from waves and extreme water levels during storms, while providing natural and recreational values. Sandy coasts are dynamic systems. Thus, risk assessments and coastal manage
Prostate cancer bone metastasis is still not fully understood, and increased knowledge could aid in the development of better treatment options for patients in the future. This thesis focuses on microRNAs (miRNAs), which modulate gene expression in healthy and tumour cells. Using cell culture, animal and patient studies, we investigated the biological role of microRNA-96 (miR-96) and microRNA-379
Adipocytes are crucial energy reservoirs to maintain metabolic homeostasis of glucose and lipids in the human body.Glucose transporters (GLUTs) and aquaporins (AQPs) play an important role in metabolic regulation of glucose andlipids in human adipocytes. Specifically, glucose transporter 4 (GLUT4) and aquaporin 7 (AQP7) are the centralplayers for glucose transport and glycerol efflux in adipocytes
Consumer research has a long tradition of examining the limits of consumer society (e.g. Schor & Holt, 2000). Overconsumption refers to a harmful and excessive type of consumption practice, which is typical of contemporary consumerism (Kjellberg, 2008). In the past, overconsumption was used synonymously with more theoretical concept such as hyper-consumption (Kilbourne et al., 1997) and afflue
Background: Breast cancer arises within specific regions in the human breast referred to as the terminal duct lobular units (TDLUs). These are relatively dynamic structures characterized by sex hormone driven cyclic epithelial turnover. TDLUs consist of unique parenchymal entities embedded within a fibroblast-rich lobular stroma. Here, we established and characterized a new human breast lobular fi
In situ CO2 and CO measurements from five Integrated Carbon Observation System (ICOS) atmosphere stations have been analysed together with footprint model runs from the regional Stochastic Time-Inverted Lagrangian Transport (STILT) model to develop a dedicated strategy for flask sampling with an automated sampler. Flask sampling in ICOS has three different purposes, namely (1) to provide an indepe
Background: To understand how the neuronal circuits in the brain process information there is a need for novelneuro-electronic interfaces that can interact chronically with brain tissue with minimal disturbance of thephysiological conditions in the tissue, in awake and freely moving animals. For this, there is a need for implantableneuro-electronic interfaces that are mechanically compliant with t
The monoamines, serotonin, dopamine, norepinephrine, epinephrine and histamine, play a critical role in the function of the hypothalamic- pituitary-adrenal axis and in the integration of information in sensory, limbic, and motor systems. The primary mechanism for termination of monoaminergic neurotransmission is through reuptake of released neurotransmitter by Na+,CI-dependent plasma membrane tran
Sediment transport in the cross-shore (CS) and associated changes in the beach profile, especially during storms, have been topics of widespread concern. Since storms are often accompanied by high water levels and large waves, large quantities of sand from the beach and the dune are typically transported offshore, leading to severe beach and dune erosion, which threatens the integrity of buildings
Forest steppes are dynamic ecosystems, highly susceptible to changes in climate, disturbances and land use. Here we examine the Holocene history of the European forest steppe ecotone in the lower Danube Plain to better understand its sensitivity to climate fluctuations, fire and human impact, and the timing of its transition into a cultural forest steppe. We used multi-proxy analyses (pollen, n-al
In an effort to mitigate global climate change, the REDD+ mechanism (an acronym for ‘Reduced Emissions from Deforestation and Forest Degradation plus the role of conservation, sustainable management of forests and enhancement of forest carbon stock’) continues to be put forward as an attractive carbon sequestration and forest conservation tool. The Democratic Republic of the Congo (DRC), hosting m
Purpose: Contribution to the understanding of defensive routines within the context of Landora Färgindustri. Research question: What are the explanatory factors behind defensive routines facing an individual within the context of their situational environment at Landora. Methodology: Mixed methods with triangulation, deduction, qualitative and quantitative methods are used. Conceptual Framework: T
Efforts to reduce energy consumption in buildings have increased with the pending impact of climate change. Heat losses through airing behaviours remain a largely unknown factor due to the variety of reasons for opening a window, making generalization difficult. Currently, an estimation of 4 kWh/m2 heated area for airing heat loss is assumed in Sweden. Additionally, the resulting airflow from open
Amelogenin, a critical protein in enamel formation, self-assembles into supramolecular structure that guide hydroxyapatite (HAP) crystal growth that is essential for the development of strong and healthy enamel. Phosphorylation of amelogenin at Ser-16 plays a pivotal role in modulating its self-assembly and functional properties, impacting the overall enamel biomineralization process. This post-tr
Over the last 30 years scientists have studied the morphological and mineralogical proofs of past aqueous activity on Mars. NASA’s latest flagship mission, the Mars 2020 mission with its Perseverance rover, landed in Jezero crater in 2021. Perseverance is tasked with investigating the wet history that has partially formed today’s Mars, and more specifically, find specific indicators for potential
Idén till det här examensarbetet föddes när vi tillsammans tillbringade en termin i London för snart tre år sedan. Vi bodde nära Hackney City Farm, en stadsbondgård i östra London. Ett stenkast från bullrande vägar och röda dubbeldäckare fanns får, kor, getter, åsnor, höns och grisar mitt i stan. Vi blev berörda och fascinerade av närheten mellan djur och människa i en urban miljö. I vårt examensInitially the idea for this thesis was born when we spent a semester together in London about three years ago. We lived close to Hackney City Farm, in the heart of eastern London. Within a stone’s throw from noisy roads and red double-deckers there were sheep, cows, goats, hens and pigs right in the middle of the city. We were fascinated and inspired by the closeness of animals and humans in a ver
Problem - Skanska Industrial Solutions AB lays asphalt over a wide geographical area, and never in the same place and is also a work that is dependent on the weather. Asphalt is a product with low to no capacity to be stored. These factors contribute to a distribution that has the necessity to follow the JIT-principles. The asphalt production is in of a steady flow of asphalt being transported fro
