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Popular Abstract in Swedish Patienter med kroniskt obstruktiv lungsjukdom, KOL, har en försämrad lungfunktion och lider av bronkit och andnöd. Dessa symptom beror troligtvis på en ständigt pågående inflammation i lungan som dels leder till ökad slemproduktion och förträngning av luftrören, dels till emfysem dvs. nedbrytning av lungvävnaden vilket försämrar gasutbytet i lungan. Cigarrettrökning är Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. The chronic inflammation in the lungs of these patients is thought to drive the pathogenesis fo

Methane emissions from Northern wetlands constitute a substantial part of the total natural emission of methane, a strong greenhouse gas. Both environmental and biotic factors influence the production, oxidation and transport of methane and hence its net flux. The methane emission from Northern wetlands is highly variable both spatially and temporally. As many factors influence the methane flux, k

Climate change has become a societal issue that has gained increasing attention in recent years. The Intergovernmental Panel on Climate Change, IPCC, presented in year 2007 its Fourth Assessment Report, pointing out different scenarios about the future climate, including the anticipated sea level rises during this century. More recent climate research has shown that sea levels are most likely to r

Ischemic heart disease is the leading cause of death in high-income parts of the world and is caused mainly by atherosclerosis in the coronary arteries. The rupture of an atherosclerotic plaque with subsequent platelet activation and clot formation can lead to myocardial infarction (MI). Atherosclerosis is a complex process, which involves the accumulation and oxidation of low-density lipoprotein

BACKGROUND: Agriculture consistently ranks as one of the highest risk industries in North America and Europe. In addition to vehicle injuries and other injuries that occur on farms, farm vehicle drivers are also involved in collisions involving tractors and other slow-moving vehicles (SMVs) on public roads. These collisions often lead to injuries among farmers, family members, farm workers, and ot

Background: Excess body weight, physical activity, smoking, alcohol consumption and certain dietary factors are individually related to colorectal cancer (CRC) risk; however, little is known about their joint effects. The aim of this study was to develop a healthy lifestyle index (HLI) composed of five potentially modifiable lifestyle factors healthy weight, physical activity, non-smoking, limited

In order to increase the understanding of suicidal behaviour, the general aim of the thesis is to gain a profound knowledge of the suicidal individual, and hence to find and ensure a preventive strategy. This will be accomplished by finding and trying new methods for evaluation of suicide risk. The Suicide Assessments Scale, SUAS, and a new self-rating version, SUAS-S were tested. These scales ar

The report, designed for interested parties of the industrial food industry in France, is founded on three research questions inspired by literature studies of sustainable development, management of corporate social responsibility, industrial food production and food product quality. The research questions search for the identification and explanation of critical categories of concern relevant for

Seven or eight thousand years ago, as the farthest the human memory can reach, the Egyptians established a great civilization that was considered as the origin of civilization on the Earth. There is no place in Egypt where man cannot find evidence that enlighten this civilization and tell about Egypt's role in most of the world's historic events from the beginning of mankind until the pres

Sediment transport in the cross-shore (CS) and associated changes in the beach profile, especially during storms, have been topics of widespread concern. Since storms are often accompanied by high water levels and large waves, large quantities of sand from the beach and the dune are typically transported offshore, leading to severe beach and dune erosion, which threatens the integrity of buildings

Forest steppes are dynamic ecosystems, highly susceptible to changes in climate, disturbances and land use. Here we examine the Holocene history of the European forest steppe ecotone in the lower Danube Plain to better understand its sensitivity to climate fluctuations, fire and human impact, and the timing of its transition into a cultural forest steppe. We used multi-proxy analyses (pollen, n-al

In situ CO2 and CO measurements from five Integrated Carbon Observation System (ICOS) atmosphere stations have been analysed together with footprint model runs from the regional Stochastic Time-Inverted Lagrangian Transport (STILT) model to develop a dedicated strategy for flask sampling with an automated sampler. Flask sampling in ICOS has three different purposes, namely (1) to provide an indepe

Background: To understand how the neuronal circuits in the brain process information there is a need for novelneuro-electronic interfaces that can interact chronically with brain tissue with minimal disturbance of thephysiological conditions in the tissue, in awake and freely moving animals. For this, there is a need for implantableneuro-electronic interfaces that are mechanically compliant with t

The monoamines, serotonin, dopamine, norepinephrine, epinephrine and histamine, play a critical role in the function of the hypothalamic- pituitary-adrenal axis and in the integration of information in sensory, limbic, and motor systems. The primary mechanism for termination of monoaminergic neurotransmission is through reuptake of released neurotransmitter by Na+,CI-dependent plasma membrane tran