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Using Multi-objective Genetic Algorithm for Site Selection of Industrial Factories
Healthcare utilization for somatic conditions among Swedish patients in opioid substitution treatment, with and without on-site primary healthcare
Background: Opioid substitution treatment (OST) populations are aging and have increased mortality and somatic morbidity compared to general populations internationally. While OST patients have poor self-rated physical health and unmet healthcare needs, documented healthcare utilization has been sparsely investigated. The aim of this study was to assess registered healthcare utilization for somati
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Interpretation of geophysical and geochemical data in a 3D geological model construction of a contaminated site
Comparison of soldier fly (Diptera: Stratiomyidae) and thick-headed fly (Diptera: Conopidae) diversity at two trapping sites
Jämförelse av två flugfamiljers mångfald i två olika naturtyper Djurs mångfald är inte bara intressant utan även viktigt för att vår värld ska fungera i harmoni och kretsloppen ska slutas och gå runt. Vissa djur behövs för att bryta ned vissna växter och andra för att hålla insekters antal i schack. Några djur kan även vara tecken på om naturen mår bra eller dåligt. Olika naturtyper är hem för olBiodiversity is a big part of the understanding of our life and its surroundings. Only a fraction of the earth’s species are known and many are yet to be found. When describing new species often both molecular and morphological data is needed to fully resolve cryptic taxa. In this study, the diversity of two Diptera families, soldier flies (Stratiomyidae) and thick-headed flies (Conopidae), have b
Management of saltpans as potential foraging sites for shorebirds
Abstract Estuaries and salt marshes are important wetlands used by waterbirds during winter and migration. However, many salt-marshes have been transformed into salinas, which currently function as high-tide roosts. Since traditional salt production is no longer profitable, many salinas have been abandoned or converted into aquaculture potentially becoming less attractive to waders. In this study
Structural and Functional Models of the Active Site of Zinc Phosphotriesterase
Novel APC-cleavage sites in FVa providing insights into mechanisms of action of APC and its cofactor protein S.
Electron paramagnetic resonance spectroscopy of site-directed spin labels reveals the structural heterogeneity in the N-terminal domain of apoA-I in solution
Apolipoprotein A-I (apoA-I) is the major protein constituent of high density lipoprotein (HDL) and plays a central role in phospholipid and cholesterol metabolism. This 243-residue long protein is remarkably flexible and assumes numerous lipid-dependent conformations. Consequently, definitive structural determination of lipid-free apoA-I in solution has been difficult. Using electron paramagnetic
Surface Alloy or Metal–Cation Interaction-The State of Zn Promoting the Active Cu Sites in Methanol Synthesis Catalysts
Model catalysts containing disordered CuO and ZnO species in the pores of SBA-15 were reduced under different conditions (standard: H2, 513 K; severe: CO/H2, 673 K), studied by X-ray diffraction (XRD) and X-ray absorption spectroscopy (XAS) including operando work and used as catalysts for methanol synthesis at pressures up to 8 bar, where they were comparable with a commercial reference in terms
Survival in cancer patients hospitalized for psoriasis: a population-based cohort study in Sweden.
Background Increased cancer risk after psoriasis has been observed in previous studies, whereas little is known about the prognosis in cancer patients with previously diagnosed psoriasis. Objectives We aimed at examining the cancer-specific and overall mortality among psoriatic cancer patients compared with the reference population. Methods The population-based Swedish registers were used to ident
Effects of baseline P-wave duration and choice of atrial septal pacing site on shortening atrial activation time during pacing.
Particle formation events measured at a semirural background site in Denmark
Azaflavones compared to flavones as ligands to the benzodiazepine binding site of brain GABA(A) receptors.
The M17 leucine aminopeptidase of the malaria parasite Plasmodium falciparum : importance of active site metal ions in the binding of substrates and inhibitors
The M17 leucine aminopeptidase of the intraerythrocytic stages of the malaria parasite Plasmodium falciparum (PfLAP) plays a role in releasing amino acids from host hemoglobin that are used for parasite protein synthesis, growth, and development. This enzyme represents a target at which new antimalarials could be designed since metalloaminopeptidase inhibitors prevent the growth of the parasites i
On exposure to anorexia nervosa, the temporal variation in axial and appendicular skeletal development predisposes to site-specific deficits in bone size and density : A cross-sectional study
Skeletal development is heterogeneous. Throughout growth, bone size is more maturationally advanced than the mineral being accrued within its periosteal envelope; before puberty, appendicular growth is more rapid than axial growth; during puberty, appendicular growth slows and axial growth accelerates. We studied women with differing age of onset of anorexia nervosa to determine whether this tempo
Discovery of the 4-aminopiperidine-based compound EM127 for the site-specific covalent inhibition of SMYD3
Simple and farmer-friendly bumblebee conservation : Straw bales as nest sites in agricultural landscapes
Nanoscale binding site localization by molecular distance estimation on native cell surfaces using topological image averaging
Antibody binding to cell surface proteins plays a crucial role in immunity, and the location of an epitope can altogether determine the immunological outcome of a host-target interaction. Techniques available today for epitope identification are costly, time-consuming, and unsuited for high-throughput analysis. Fast and efficient screening of epitope location can be useful for the development of t
