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Assessing the effects of mining projects on child health in sub-Saharan Africa : a multi-country analysis
Background: The African continent hosts many industrial mining projects, and many more are planned due to recent prospecting discoveries and increasing demand for various minerals to promote a low-carbon future. The extraction of natural resources in sub-Saharan Africa (SSA) represents an opportunity for economic development but also poses a threat to population health through rapid urbanisation a
Epithelioid and Spindle Cell Hemangioma : Clinicopathologic Analysis of 18 Primary Bone and Soft Tissue Tumors Highlighting a Predilection for the Hands and Feet, Frequent Multicentricity, and Benign Behavior
Epithelioid and spindle cell hemangioma was initially described in 1999 in a series of primary bone tumors and was subsequently suggested by some to represent a variant of epithelioid hemangioma. Here, we studied 18 epithelioid and spindle cell hemangiomas. Nine patients (50%) were male. Age at presentation ranged from 12 to 78 years (median: 38.5 y). Nine patients (50%) had tumor(s) limited to bo
A numerical model to simulate short-term beach and dune evolution
Sediment transport in the cross-shore (CS) and associated changes in the beach profile, especially during storms, have been topics of widespread concern. Since storms are often accompanied by high water levels and large waves, large quantities of sand from the beach and the dune are typically transported offshore, leading to severe beach and dune erosion, which threatens the integrity of buildings
North Atlantic marine biogenic silica accumulation through the early to middle Paleogene : Implications for ocean circulation and silicate weathering feedback
To continue or not to continue? Antipsychotic medication maintenance versus dose-reduction/discontinuation in first episode psychosis : HAMLETT, a pragmatic multicenter single-blind randomized controlled trial
Background: Antipsychotic medication is effective for symptomatic treatment in schizophrenia-spectrum disorders. After symptom remission, continuation of antipsychotic treatment is associated with lower relapse rates and lower symptom severity compared to dose reduction/discontinuation. Therefore, most guidelines recommend continuation of treatment with antipsychotic medication for at least 1 year
Transnasal Evaporative Cooling in Out-of-Hospital Cardiac Arrest Patients to Initiate Hypothermia—A Substudy of the Target Temperature Management 2 (TTM2) Randomized Trial
Background: In animal models, early initiation of therapeutic cooling, intra-arrest, or restored circulation has been shown to be neuroprotective shortly after cardiac arrest. We aimed to assess the feasibility and cooling efficacy of transnasal evaporative cooling, initiated as early as possible after hospital arrival in patients randomized to cooling in the TTM2 trial. Methods: This study took t
Multiscale pollen-based reconstructions of anthropogenic land-cover change in Karula Upland, south Estonia
Pollen-based quantitative vegetation reconstructions using multiple sedimentary basins from the same area, along with their quantified relevant pollen source areas, are a powerful means to study how long-term human impact has affected vegetation and shaped the currently protected heritage landscapes at different spatial scales. Our study presents the outcome of a palynological investigation in Kar
Falls Predict Fractures Independently of FRAX Probability : A Meta-Analysis of the Osteoporotic Fractures in Men (MrOS) Study
Although prior falls are a well-established predictor of future fracture, there is currently limited evidence regarding the specific value of falls history in fracture risk assessment relative to that of other clinical risk factors and bone mineral density (BMD) measurement. We therefore investigated, across the three Osteoporotic Fractures in Men (MrOS) Study cohorts, whether past falls predicted
Integrated approach to investigate groundwater nitrate nitrogen pollution and remediation simulation in Shimabara Peninsula, Nagasaki, Japan
Groundwater is the general source of drinking water in the Shimabara Peninsula, Nagasaki, Japan, and consequently, occurring nitrate nitrogen (NO3-N) pollution in the groundwater is a significant problem. Although various countermeasures have been implemented, nitrate nitrogen concentrations remain serious. Therefore, it is necessary to evaluate effects of different potentially effective counterme
A clinical study of efficacy and safety of the Carry Life UF system in continuous ambulatory peritoneal dialysis patients : protocol for a prospective, multicenter, randomized, crossover study
Background: Carry Life UF is a novel peritoneal dialysis (PD) technology for improved fluid management using steady concentration PD (SCPD). The Carry Life UF treatment starts with a manual peritoneal fill of 1.36% glucose PD fluid, followed by a 5-hour treatment where small amounts of glucose are continuously added to maintain a stable intraperitoneal glucose concentration. A recent in-center cli
Pre- or postoperative radiotherapy for oral cancer - Does the treatment order matter?
Bakgrund: Den kurativa behandlingen för resektabla lokalt avancerade stadier av cancer i munhålan innefattar i regel en kombination av kirurgi och radioterapi (RT). Huruvida RT bör ges först och därefter följas av kirurgi, eller om tumören bör opereras bort först, följt av RT postoperativt, har dock inte studerats i någon större omfattning.Syfte: Denna avhandling undersöker olika aspekter av pre- Background: The curatively intended treatment for resectable locally advanced stages of oral cavity cancer (OCC) generally involves a combination of surgery and radiotherapy (RT). However, whether to apply RT first and then proceed with surgery, or to resect the cancer and subsequently administer RT, has not been extensively studied. Aims: This thesis examines various aspects of pre- versus postop
New insights into the atmospheric dust dynamics in the Carpathian and Wallachian Basin during MIS 1-MIS 2
Fine-grained windblown deposits, known as loess, in which fossil soils (palaeosols) are preserved, serve as excellent records of past climate. However, paleoclimate reconstruction studies on loess-palaeosol sequences (LPS) in Southeastern Europe have primarily focused on climate changes during the last one or two glacial-interglacial cycles. Surprisingly, little attention has been given to the cli
Industrial Food Quality - Policy and Management in Favour of Sustainable Development. A study of the French food sector
The report, designed for interested parties of the industrial food industry in France, is founded on three research questions inspired by literature studies of sustainable development, management of corporate social responsibility, industrial food production and food product quality. The research questions search for the identification and explanation of critical categories of concern relevant for
Relating interannual variability of atmospheric CH4 growth rate to large-scale CH4 emissions from northern wetlands
Metan (CH4) är en av de viktigaste växthusgaserna i atmosfären och dess kraftiga ökning har bidragit till den uppvärmning som vi har upplevt fram till idag. Sedan mitten av 1980-talet påvisar mätningar att metantillväxten i atmosfären har börjat fluktuera från år till år. Orsakerna till detta är omstridda och ännu inte klargjorda. Under 2007 uppmättes en kraftig ökning i tillväxt som vaThe increasing atmospheric concentration of the greenhouse gas methane (CH4) is highly relevant for current and future global warming. Since the mid-1980s atmospheric measurements have revealed large interannual fluctuations in methane growth rate. However, the causes of this feature are still not well understood. In 2007, a peak in growth rate appears to have been particularly strong a
Defensive routines and their origins
Purpose: Contribution to the understanding of defensive routines within the context of Landora Färgindustri. Research question: What are the explanatory factors behind defensive routines facing an individual within the context of their situational environment at Landora. Methodology: Mixed methods with triangulation, deduction, qualitative and quantitative methods are used. Conceptual Framework: T
Retargeting of the IS608 Transposon
DNA transposons are a class of mobile genetic elements that can autonomously move from one genomic location to another. They are powerful drivers of genetic change and have played a significant role in the evolution of many genomes. One such transposable element, IS608 from Helicobacter pylori employs a unique mechanism of transposition as it transposes in a single-stranded DNA form and inserts sp
Lufttäthet i klimatskalet hos temporära byggnader uppförda med husmoduler
The industrialization of the Swedish construction industry has long stood in the shadow of the traditional construction methods. Problems such as high costs, long construction times and tough regulations have made the development stagnate. However, the industrial manufacturing industry has shown rapid growth within recent years. The culture within the industry has changed through innovative constr
Bristande logik på Furutorpsgatan - Problembeskrivning och åtgärdsförslag
Defective logic on Furutorpsgatan - An identification of present problems and proposed measures Helsingborg City is in the progress to make new maintenance measures on Furutorpsgatan. In relation to that, improvements to the streetscape, is also planned. Therefore a description on which problems that occurs with the current design of Furutorpsgatan, and possible measures to improve the situation h
Mifo fas 1 som inventeringsmetod för bedömning av föroreningspåverkan vid fastställande av vattenskyddsområde för Stångån.
MIFO (Metodik för Inventering av Förorenade Områden) används för att inventera potentiellt förorenade mark- och vattenområden i Sverige. Metoden började användas på 1990-talet och utgör sedan dess en mall för inventering. En MIFO-inventering består av två faser, fas-1 och fas-2. I respektive inventeringsfas tilldelas objektet en riskklass mellan 1-4. Till följd av ett omfattande inventeringsarbete
