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Combinatorial Synthesis of Pilicides

This thesis describes a combinatorial approach to design and synthesis of three libraries of compounds, referred to as pilicides, designed to target periplasmic chaperones present in uropathogenic Escherichia coli bacteria that are the main cause of urinary tract infections. Periplasmic chaperones are required for assembly of adhesive organelles, i.e. pili, which recognize and bind to specific rec

NMR Studies of Bacterial Albumin-Binding Modules

Popular Abstract in Swedish Proteiner är uppbyggda av aminosyror som är hopkopplade med varandra och bildar långa kedjor som kan bestå av hundra- eller tusentals aminosyror. Det finns en mängd olika proteiner och de har många olika funktioner. I studierna som beskrivs här, har proteiner som finns på ytan av vissa bakterier studerats. De långa proteinkedjorna i dessa bakteriella ytproteiner är oftPeptostreptococcus magnus and group C/G streptococci are Gram-positive cocci that are part of the normal flora and reside in more or less the same locations in the host. Protein G of group C/G streptococci was originally described as binding IgGFc of several species and later shown to also bind human serum albumin and albumins from various animal species. From albumin-binding strains of P. magnus

The Plasma Membrane H+-ATPase - Identification of a 14-3-3 binding motif

The P-type plasma membrane H+-ATPases form a group of proteins only found in plants and fungi. The pumping of protons across the plasma membrane, energized by ATP hydrolysis, creates an electrochemical gradient that is essential for solute transport and internal pH regulation. The H+-ATPase genes are present as multigene families in the genomes of higher plants and all cell t

Small-scale climate variability and its ecosystem impacts in the sub-Arctic

Abstract in Undetermined To improve our knowledge of climate change and its impacts on ecosystem services, and to inform local people and governments that need assistance with the development of mitigation and adaptation strategies, climate impacts need to be understood urgently at the smaller scale. On one hand, the microclimate/topoclimate is known to be strongly decoupled from the general macro

A Surface Temperature Initiated Closure (STIC) for surface energy balance fluxes

The use of Penman-Monteith (PM) equation in thermal remote sensing based surface energy balance modeling is not prevalent due to the unavailability of any direct method to integrate thermal data into the PM equation and due to the lack of physical models expressing the surface (or stomatal) and boundary layer conductances (g(S) and g(B)) as a function of surface temperature. Here we demonstrate a

Geographical variation and systematics of the tetraploid marsh orchid Dactylorhiza majalis subsp sphagnicola (Orchidaceae) and closely related taxa

Dactylorhiza majalis subsp. sphagnicola is an allotetraploid marsh orchid derived from parents closely similar to present-day D. incarnata and the western European form of D. maculata subsp. maculata, suggesting that it has a postglacial origin. It extends from northwestern continental Europe into areas formerly covered by the Weichselian ice sheet in mid-Scandinavia. Here, we studied the variatio

Peatland dynamics in response to past and potential future climate change : A regional modelling approach

En majoritet av de nordliga torvmarkerna utvecklades under holocen som ett resultat av en positiv massbalans mellan nettoprimärproduktion och heterotrofa nedbrytningshastigheter. Sedan dess har de lagrat stora mängder kol i terrestra ekosystem. En betydande del av dessa områden sammanfaller också med regioner med underliggande permafrost och uppvisar olika ackumulationsmönster av torv. Således, föThe majority of the northern peatlands developed during the Holocene as a result of a positive mass balance between net primary productivity (NPP) and heterotrophic decomposition rates. Over that time they have sequestered a huge amount of carbon in terrestrial ecosystems. A significant proportion of these areas also coincides with areas underlain with permafrost and shows a diverse range of peat

ONSHORE WINDMILL FOUNDATIONS - Evaluation of new proposals

Windmill structures must withstand very high horizontal loading giving an extremely large overturning moment on the foundation. These structures have very low stability loads in comparison to the overturning loads. The traditional way to solve the construction problem uses a shallow foundation with a massive concrete volume or a piled foundation to resist the extreme overturning moment. This work

Transcriptional Analysis of Cell-Sorted B-cell Lymphomas From High-throughput to Focused Identification of Molecular Targets

B cell lymphomas (BCLs) are a group of severe cancers, afflicting both men and women at different ages. Gene expression profiling (GEP), have during the latest decades fundamentally contributed to a better classification and biological understanding of the different BCLs. Most studies using GEP have analyzed mRNA from tumor tissue constituted of both tumor cells and non-malignant bystander cells.

Effect of tailored dose-dense chemotherapy vs standard 3-weekly adjuvant chemotherapy on recurrence-free survival among women with high-risk early breast cancer : A randomized clinical trial

IMPORTANCE Standard dosing of chemotherapy based on body surface area results in marked interpatient variation in pharmacokinetics, toxic effects, and efficacy.Whether tailored dosing can improve outcomes is unknown, as is the role of dose-dense adjuvant chemotherapy. OBJECTIVE To determine whether tailored dose-dense adjuvant chemotherapy improves the outcomes of early breast cancer compared with

Application of Laser Techniques in Combustion Environments of Relevance for Gas Turbine Studies

Popular Abstract in Swedish Oberoende av vilket bränsle som används ger förbränning upphov till utsläpp av miljöfarliga gaser, såsom kväveoxider, svaveldioxider, kolmonoxid och oförbrända kolväten. Dessa ämnen bidrar till försurning, smog, växthuseffekten och kan skada ozonlagret. Även koldioxid kan anses som en miljöfarlig gas då den bidrar till den globala uppvärmningen. För att få en bättre förIn the work presented in this thesis, different laser-based techniques were employed for measurements in different combustion devices. Laser-based techniques enable non-intrusive and in-situ measurements to be carried out, in which high spatial and temporal resolution can be obtained. Different parameters related to combustion research can be visualized, such as species concentrations, temperature

Estimating source area of pollen and pollen productivity in the cultural landscapes of southern Sweden - developing a palynological tool for quantifying past plant cover

Popular Abstract in Swedish Den här avhandlingen är ett bidrag till utvecklingen av en metodik som gör det möjligt att med hjälp av fossila pollen d.v.s. pollen som lagrats i mossar och sjöar, rekonstruera historiska och förhistoriska landskap så precist som möjligt vad gäller utbredning av skog, olika typer av öppen mark samt vegetationens sammansättning. Den tolknings metodik som för närvarande Fossil pollen records retrieved from peat and lake sediments have great potential for quantifying past plant cover. This thesis is a contribution to the development of a palynological interpretation tool for reconstructing past cultural landscapes in terms of plant abundance and distribution. The aims of this thesis are (1) to explore pollen-vegetation relationships in the ancient, traditional cul

General Syllabus 2015-11-11

Brevmall Board of the F acul ty o f Law English translation of the Swedish original, which remains the only authentic one. General syllabus for doctoral studies for completion of the degrees DOCTOR OF LAWS and LICENTIATE OF LAWS at the Law Faculty, Lund University 1. Identification Subjects: Jurisprudence, labour law, banking law, private law, EU law, fiscal law, public international law, administ

https://www.law.lu.se/sites/law.lu.se/files/2023-07/General%20Syllabus%202015-11-11.pdf - 2026-05-28

Ademun stella rose 1

Microsoft Word - Ademun_Stella_Rose_Lumes_thesis_final Domestic Water Supply: An Evaluation of the Impacts; Challenges and Prospects on Women in Rural Households in Uganda A thesis submitted in partial fulfillment of the requirement for the award of a degree of Masters of Science May 2009 Author Supervisor Stella Rose Ademun Johanna Alkan Olsson (PHD) LUMES, Lund University LUCSUS, Lund University

https://www.lumes.lu.se/sites/lumes.lu.se/files/ademun_stella_rose_1.pdf - 2026-05-28

Taguchi toru

Lumes Lund University International Master's Programme in Environmental Science Master Thesis Minimized Energy, Water and Transport Utilization in Urban areas: - A cage study of Musashino city, Tokyo Japan- Torn Taguchi 3-12-16 Yayoicho Nakano-ku, 164-0013, Tokyo, Japan Phone number: +81 (0)3 3372 8604 Sopervisor: Msc, Doctorai Candidate, Max Åhman Department of Environmental and Energy Systems St

https://www.lumes.lu.se/sites/lumes.lu.se/files/taguchi_toru.pdf - 2026-05-28

Ms2011-3 0

Uppsatsmall MELLAN DELTAGANDE OCH INFLYTANDE En kartläggning av brukarråd i Skånes kommuner HÅKAN JOHANSSON, LINN JOHANSSON & ROBERTO SCARAMUZZINO MEDDELANDE FRÅN SOCIALHÖGSKOLAN, LUNDS UNIVERSITET, 2011:3 Mellan deltagande och inflytande: En kartläggning av brukarråd i Skånes kommuner Håkan Johansson, Linn Johansson & Roberto Scaramuzzino Meddelande från Socialhögskolan, Lunds universitet, 2011:3

https://www.soch.lu.se/sites/soch.lu.se/files/ms2011-3_0.pdf - 2026-05-28

Kartläggning av tungmetaller uppströms Himmerfjärdsverket : en studie av möjliga källor till kadmium och nickel i avloppsslam

Slam från konventionell avloppsvattenrening innehåller näringsämnen samt mullbildande ämnen vilket medför att materialet utgör en resurs som växtnäring och jordförbättringsmedel. Problematiken med att använda slam är att det även innehåller främmande ämnen som metaller och svårnedbrytbara organiska föreningar. Syvab är ett kommunalt bolag som driver Himmerfjärdsverket men ansvarar också för någrSludge is produced in conventional waste water treatment. The sludge contains nutrients and humic formaing substances which make it useful as a fertilizer. The problem with using sludge is that it also contains toxicants as heavy metals and persistent organic compounds. Syvab is a municipal owned corporation that manage the wastewater treatment plant Him-merfjärdsverket. Since August 2010 Himmer

Behandling av personuppgifter på grund av berättigat intresse i marknadsföringssyfte - Dataskyddsförordningens påverkan på intresseavvägningen enligt artikel 6 punkt f mellan integritetsintresset och kommersiella intressen

Denna uppsats undersöker vilka möjligheter en privat organisation har att använda sig av personuppgifter utan samtycke på grund av ett så kallat ”berättigat intresse” enligt personuppgiftslagen (1998:204) samt lagen om elektronisk kommunikation (2003:389). Ett berättigat intresse föreligger när behandling av en uppgift är nödvändig för ett ändamål hos den personuppgiftsansvarige eller en tredje paThis thesis examines the possibilities of a private entity to use personal data without consent, based on a so called "legitimate interest" in accordance with the personal information act (1998:204) and the electronic communications act (2003:389). A legitimate interest is in effect when processing of a piece of personal information is necessary for the liable party or a third party with

Identifying Drivers and Mechanisms of Climate-Related Tree Mortality

Eastern New South Wales (NSW), Australia, is a region prone to frequent and intense droughts. An unprecedented episode of high temperatures and low rainfall in 2017–2019 culminating in the 2019-2020 summer triggered massive canopy dieback of eucalypt forests throughout the region. Subsequent high rainfall in 2020 offered a unique and rare opportunity to study the process of vegetation recovery fol