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Selective mutation in ATP-binding site reduces affinity of drug to the kinase: a possible mechanism of chemo-resistance
Spatial variability of soil fungal and bacterial abundance: Consequences for carbon turnover along a transition from a forested to clear-cut site
Predicted alterations in belowground plant-allocated C as a result of environmental change may cause compositional shifts in soil microbial communities, and it has been hypothesized that such alterations will influence C mitigation in forest ecosystems. In order to investigate to what degree living trees influence the abundance and activity of mycorrhizal fungi, saprotrophic fungi, and bacteria we
Interpreting canopy development and physiology using a European phenology camera network at flux sites
Plant phenological development is orchestrated through subtle changes in photoperiod, temperature, soil moisture and nutrient availability. Presently, the exact timing of plant development stages and their response to climate and management practices are crudely represented in land surface models. As visual observations of phenology are laborious, there is a need to supplement long-term observatio
Does immigration play a role in the risk of gastric cancer by site and by histological type? A study of first-generation immigrants in Sweden
The observed increased risks of gastric cancer among first-generation immigrants compared to those in Swedes suggest the role of childhood environmental exposure in the risk of this disease.
Carbon dioxide ion dissociations after inner shell excitation and ionization: The origin of site-specific effects.
Multi-coincidence experiments with detection of both electrons and ions from decay of core-excited and core-ionized states of CO2 confirm that O2 (+) is formed specifically in Auger decay from the C1s-π* and O1s-π* resonances. Molecular rearrangement occurs by bending in the resonant states, and O2 (+) is produced by both single and double Auger decay. It is suggested that electron capture by C(+)
Rules for priming and inhibition of glycosaminoglycan biosynthesis; probing the beta 4GalT7 active site
beta-1,4-Gatactosyltransferase 7 (beta 4GalT7) is an essential enzyme in the biosynthesis of glycosaminoglycan (GAG) chains of proteoglycans (PGs). Mammalian cells produce PGs, which are involved in biological processes such as cell growth and differentiation. The PGs consist of a core protein, with one or several GAG chains attached. Both the structure of the PGs and the GAG chains, and the expre
Paleogeographical Reconstruction and Management Challenges of an Archaeological Site Listed by UNESCO: Case of the Plain of Xanthos and Letoon (Turkey)
Living at the margin of the retreating Fennoscandian ice sheet : the early mesolithic sites at Aareavaara, northernmost Sweden
Acoustic trapping as a generic non-contact incubation site for multiplex bead-based assays.
In this study, we show a significantly reduced assay time and a greatly increased bead recovery for a commercial Luminex-based multiplex diagnostic immunoassay by performing all liquid handling steps of the assay protocol in a non-contact acoustic trapping platform. The Luminex assay is designed for detecting antibodies in poultry serum for infectious bursal disease virus, infectious bronchitis vi
The unique structure of Haemophilus influenzae protein E reveals multiple binding sites for host factors.
Haemophilus influenzae protein E (PE) is a multifunctional adhesin, involved in direct interactions with lung epithelial cells and host proteins, including plasminogen and the extracellular matrix proteins vitronectin and laminin. We recently crystallized PE and successfully collected X-ray diffraction data to 1.8 Å. Here we solved the structure of a recombinant version of PE and analyzed differen
Simultaneous assimilation of satellite and eddy covariance data for improving terrestrial water and carbon simulations at a semi-arid woodland site in Botswana
A web site analysis of music teacher education in Europe - A study of six countries
The present study is a part-study of the EVEDMUS (evaluation of teacher education in music) project aiming to examine the music teacher education programmes across Europe and Latin America. The overarching objective of the EVEDMUS project is to learn about the different conditions and causes in which the musical and educational knowledge is being constructed and identify factors in the programmes
To Buy or Not to Buy: Standards and practices of assessing environmental aspects of sites and companies
This research set out to describe the current state of Environmental due iligence, how it evolved, current trends, and where it may be headed. The approach taken to accomplish this was a literature review, comparison of international Environmental due diligence standards, in particular ASTM E-1527 00 and ISO 14015, review of six case studies of environmental due diligence assessment reports, and i
Testing the effect of site selection and parameter setting on REVEALS-model estimates of plant abundance using the Czech Quaternary Palynological Database
REVEALS-based quantitative reconstruction of Holocene vegetation cover (expressed in plant functional types. PFTs) is used in the LANDCLIM project to assess the effect of human-induced land-cover change on past climate in NW Europe. Using the Czech Quaternary Pollen Database, this case study evaluates the extent to which selection of data and input parameters for the REVEALS model applications wou
Polymorphisms in the promoter region and intron 1 of the estrogen receptor alpha gene including a novel glucocorticoid responsive site are associated with bone mineral density in 75-year old Swedish women ( Abstracts of the 35th European Symposium on Calcified Tissues)
Can a web-site constitute an establishment for the purposes of jurisdiction and applicable law?
Towards a full greenhouse gas budget at a clear-cut and stump harvested boreal forest site in Sweden
Exploration of conformational flexibility and hydrogen bonding of xylosides in different solvents, as a model system for enzyme active site interactions
The predominantly populated conformation of carbohydrates in solution does not necessarily represent the biologically active species; rather, any conformer accessible without too large an energy penalty may be present in a biological pathway. Thus, the conformational preferences of a naphthyl xyloside, which initiates in vivo synthesis of antiproliferative glycosaminoglycans, have been studied by
Analysis of particle size distribution changes between three measurement sites in northern Scandinavia
We investigated atmospheric aerosol particle dynamics in a boreal forest zone in northern Scandinavia. We used aerosol number size distribution data measured with either a differential mobility particle sizer (DMPS) or scanning mobility particle sizer (SMPS) at three stations (Varrio, Pallas and Abisko), and combined these data with the HYSPLIT (Hybrid Single Particle Lagrangian Integrated Traject
