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The human epidermal growth factor receptor 2 (HER2) is a receptor tyrosine kinase that is involved in many cellular pathways. The HER2 locus is amplified in 12-21% of all breast cancers and is associated with poor prognosis. The introns of HER2 contain two non-coding RNAs: a microRNA (miRNA) named mir-4728 and a box C/D snoRNA-like molecule thus far named snoID_0714. In this study, a list of targe
This thesis views Sankt Lars begravningsplats (cemetery) as a deathscape where histories of institutionalization, social exclusion, and neoliberal expansion are spatially materialized in the cemetery’s ecology. Tied to the former Sankt Lars asylum on the margins of Lund, Sweden, the cemetery embodies the intersections of human and nonhuman forces where ecological transformations intertwine with cu
State-controlled social media platforms can result in authoritarian soft power assets when the users' mediated communication extends across borders. Especially in times of hostile conflict and narrative divide, these transnational communication networks – without the coordination of the authoritarian state – can promote authoritarian narratives to non-domestic audiences when multilingual users
Critical scholarship has increasingly questioned the effectiveness of external menstrual health interventions in the Global South, often highlighting their lack of cultural sensitivity and potential to reinforce menstrual stigma. These critiques raise concerns not only about individual well-being, but also about broader questions of gendered inequality. Although such initiatives frequently center
This study explores how everyday ferry travel in transit spaces create experiences through the interplay of mundane and extraordinary interactions, focusing on the Øresundslinjen ferry between Helsingborg, Sweden, and Helsingør, Denmark. Drawing on the concepts of mundane tourism, the new mobilities paradigm, tourist gaze, and service-scape theories were used to examine the social, spatial, and em
Denna uppsats närmar sig svenskt plein-air måleri i Fontainebleau och inom konstnärskolonin Grèz-sur-Loing från slutet av 1800-talet genom längtans lins. Med utgångspunkt i temat nostalgi och apodemialgi – längtan hem och längtan att bort – undersöks landskapsmåleriet och hur det visualiserar teman om natur och modernitet. Denna tid av exil är en viktig punkt i svensk konsthistoria eftersom den haThis thesis examines late 19th-century Swedish plein-air painting in Fontainebleau and within the artists’ colony Grèz-sur-Loing through the lens of longing. Drawing on the theme of nostalgia and apodemialgia—longing for home and the longing to leave—it investigates how landscape painting visualizes themes of nature and modernity. This time of exile is an important point in Swedish art history as
This thesis investigates the hydrosocial territory of Sicily through a political ecology lens, analysing how water insecurity is due to climate change, state absence, socio-political fragmentation. Although water is physically present on the island, its mismanagement, shaped by clientelism, infrastructural decay, and political dysfunction, produces a sense of insecurity, exacerbating social inequa
This master thesis investigates how a manufacturing company develops and implements packaging solutions for sustainable development, using ASSA ABLOY as a case study. Focusing on the sliding door operator produced at a manufacturing plant in Eastern Europe, the study explores the environmental and economic impacts of packaging throughout its life cycle and the internal packaging innovation process
Drug use is governed today by a global prohibition regime that medicalizes and criminalizes people who use drugs, producing marginalization, risk environments, and illicit markets. In parallel, digital platformization has enabled darknet cryptomarkets to reorganize drug distribution and create new social contexts in which drugs, markets, and users are discursively constructed. This thesis examines
Detta examensarbete syftar till att identifiera företag som äger sina verksamhetsfastigheter samt analysera deras förutsättningar att genomföra energieffektiviserande åtgärder. Studien baseras på kommunal registerdata, geografisk analys via Geoportalen samt kvalitativ verifiering genom platsbesök och semistrukturerade företagsintervjuer. Resultaten indikerar att ägarstruktur har stor betydelseEnergy efficiency initiatives targeting businesses often face challenges related to identifying actors with the authority to implement measures. This study examines how property ownership influences companies’ ability to undertake energy efficiency actions. The study was conducted as a case study in Lund municipality and applied a two-step methodology consisting of registry-based mapping and qual
Streets of Recovery explores how urban environments affect stress levels and how streets can be designed to support well-being. While existing research largely emphasises parks and green spaces, this study focuses on streets as everyday environments with the potential to influence stress. If urban environments shape stress levels, they also hold the potential to mitigate them. The thesis examines
The UK achieved the ambitious goal of becoming the first G7 country to phase out coal-firedelectricity, with its last power station, Ratcliffe-on-Soar closing in 2024. Ensuring thisgeneration of transitioning communities does not follow in the footsteps of ‘left behind’ UKex-mining villages for example, is imperative. This study investigates and compares theimaginaries of place leaders and locals
Transpiration drives up to 40 % of terrestrial precipitation, with forests playing a critical role. This study combines long-term sap flow measurements and surface-based cloud observations to examine how different clouds affect tree transpiration across boreal and temperate European forests. Under specific cloudy conditions, sap flow can exceed clear-sky levels, reflecting distinct radiation effec
Accurate and continuous monitoring of inland surface water dynamics is vital for sustainable water resource management, climate impact assessment, and ecological planning. This study introduces a machine learning-based remote sensing-based data-fusion framework that improves Sentinel-3 radar altimeter (SRAL) estimations of water surface elevation (WSE) by integrating ERA5 reanalysis climate varia
The oxygen reduction reaction (ORR) on platinum is limited by a substantial overpotential, which hampers the efficiency of fuel cell technologies. While adsorbate binding energies have been widely used to explain ORR kinetics, we here illustrate a more complex role of platinum surface oxides, which are often ambiguously defined in the literature. We use operando total reflection X-ray absorption f
Alterations in cortical morphology have consistently been reported in obsessive-compulsive disorder (OCD). However, the microstructural properties of the cortex in OCD, including intracortical myelination, remain far less explored. The contrast between signal intensity in gray and subjacent white matter from T1-weighted magnetic resonance imaging (MRI), i.e. the gray/white matter contrast (GWC), i
The Quercetum Chorus Workshop introduced students in the Cal Poly Pomona Interdisciplinary Paris Study Abroad Program (CPP IPSAP) to methods of deepening human-tree relations through sound, drawing and movement. Students applied a multi-sensory approach to knowing trees by attuning to their frequencies, textures, shapes, and movements. They were invited to reimagine trees as more-than-human bodies
Natural products are emerging as valuable tools in insect pest management, particularly as synergists that enhance insecticidal activity while potentially reducing chemical usage and mitigating resistance. This chapter explores the role of natural products in boosting the efficacy of both synthetic and botanical insecticides. First, the chapter focuses on the current regulatory status of synergist
Mutations in MLC1 cause megalencephalic leukoencephalopathy with subcortical cysts (MLC), a rare form of leukodystrophy characterized by macrocephaly, epilepsy, spasticity, and slow mental deterioration. Genetic studies of MLC are lacking from many parts of the world, especially in Sub-Saharan Africa. Genomic DNA was extracted for 67 leukodystrophic patients from 43 Sudanese families. Mutations we
