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Background: The Swedish Breast Reconstruction Outcome Study (SweBRO) initiative is a nationwide study with the primary aim of assessing long-term outcomes after mastectomy with and without breast reconstruction (BR). The current part (SweBRO 2) is designed to evaluate health-related quality of life (HRQoL), with the hypothesis that BR has a positive impact on patient-reported HRQoL in the long-ter

This report is an external evaluation of the scientific basis of the Norwegian assessment system for ecological condition (Fagsystem for økologisk tilstand), commissioned by the Ministry of Climate and Environment (KLD). Two assessment methods are currently used for various terrestrial and marine ecosystems: the Panel-Based Assessment of Ecological Condition (PAEC) and the Index-Based Ecological CThis reportis an external evaluation of the scientific basis of the Norwegian assessment system for ecological condition, commissioned by the Ministry of Climate and Environment. Two assessment methods are currently used for various terrestsrial and marine ecosystem: the Panel-Based Assessment of Ecological Condition (PAEC) and the Index-Based Ecological Condition Assessment (IBECA). The purpose o

Popular Abstract in Swedish Populärvetenskaplig sammanfattning Felaktig DNA-reparation av typen mismatch repair (MMR) uppkommer i 15-17% av cancer i tjock- och ändtarm (kolorektalcancer). MMR defekter är av betydelse i tre situationer: • MMR defekta tumörer har en bättre prognos än övrig tjock- och ändtarmscancer, vilket kan användas för att avgöra huruvida en patient skall erbjudas sk. adjuvant Mismatch repair (MMR) deficiency is carcinogenic and can either have somatic/sporadic causes (i.e. epigenetic silencing or somatic inactivation) or hereditary causes (Lynch syndrome due to a germline mutation in one of the MMR genes ¬- MLH1, MSH2, MSH6, PMS2). The identification of MMR defective colon cancer is clinically relevant for diagnostic, prognostic and potentially also for treatment-predi

Background: The prevalence of blindness and visual impairment from glaucoma is influenced by the criteria used to define these entities, which differ between countries and regions, as well as among published reports. The objective of the present study was to ascertain the extent to which different criteria of blindness and visual impairment influence estimates of the number of patients classified

Our knowledge about acute promyelocytic leukemia (APL) patients is mainly based on data from clinical trials, whereas population-based information is scarce. We studied APL patients diagnosed between 1997 and 2006 in the population-based Swedish Adult Acute Leukemia Registry. Of a total of 3897 acute leukemia cases, 3205 (82%) had non-APL acute myeloid leukemia (AML) and 105 (2.7%) had APL. The in

Background: The US Environmental Protection Agency voluntary phased-out residential use of chlorpyrifos in 2001. In contrast, in Costa Rica, chlorpyrifos-treated bags are increasingly used to protect banana and plantain fruits from insects and to fulfill product standards, even in populated areas. Objectives: To evaluate children's exposure to chlorpyrifos in villages situated nearby banana planta

Liming is a forest practice used to counteract forest decline induced by soil acidification. It consists of direct Ca and Mg input in forest soil and restores tree mineral nutrition, but also causes drastic changes in nutrient availability in soil. Ectomycorrhizal (ECM) fungi significantly contribute in nutrient uptake by trees, and can recover them through organic acid secretion or through enzyma

BACKGROUND: Decreased glomerular filtration rate is an established risk factor for bleeding but there are limited data on its association with bleeding risk in well-controlled anticoagulated patients taking warfarin. OBJECTIVES: The aim was to investigate the relationship between glomerular filtration rate, major bleeding and thromboembolic complications in patients with tight anticoagulation cont

Objectives To assess 2-year durability of joint contracture correction following collagenase injections for Dupuytren's disease. Design Prospective cohort study. Setting Orthopaedic Department in Sweden. Participants Patients with palpable Dupuytren's cord and active extension deficit (AED) ≥30° in the metacarpophalangeal (MCP) and/or proximal interphalangeal (PIP) joint. A surgeon injected 0.80 m

Both genetic and lifestyle factors contribute to the risk of non-alcoholic steatohepatitis (NASH). Additionally, epigenetic modifications may also play a key role in the pathogenesis of NASH. We therefore investigated liver DNA methylation, as a marker for epigenetic alterations, in individuals with simple steatosis and NASH, and further tested if these alterations were associated with clinical ph

This study aims to examine the topic of innovation in China. The need for innovative development is of importance for the nation to keep the rapid development. A few evaluations of both Chinas indigenous innovation policy and the opportunities for the citizens to develop innovation has criticized the lack of creativity in human resources and the examination based education system to be harmful for

Public transport affects people on a daily basis and therefore it is important for the public transport sector to improve the user experience for travellers. Simplicity is a keyword in the improved user experience where mobile solutions play an important role for the experience. The aim in this master thesis is to explore ways how to use a smartphone to make it easier for travellers and how to pre

Laundry as a household activity has been subject to (un)sustainable consumption studies. The majority of those studies are rooted in mainstream approaches to (un)sustainable consumption focusing on either changing individuals (e.g., their decisions, behaviors, habits) or system (e.g., infrastructure, technology). Moreover, the laundry has been predominantly studied as a washing activity. This rese

In recent years there have been frequent reports of a high workload and poor working conditions for social workers employed in social services where reports have shown that social services have had a high employee turnover. It is also common that the work the social workers do is characterised by difficult assessments and decisions which can result in a large amount of pressure to perform in accor

This thesis is divided into two parts (1&2) with different but related scopes, they are both partly a response to Volvo Truck Australia's (VTA) wish to improve their supply chain. In 1998 this wish resulted in a global benchmark, of VTA's total inbound transports, being submitted to 13 global transporting companies. Being one of the responding companies, Volvo Transport delegated the d

Under vilka förutsättningar kan ett effektivt samarbete komma till stånd vid humanitära insatser? Den omfattande jordbävningen i Pakistan 2005 kallade till sig ett stort antal aktörer, däribland Röda Korset, Oxfam och CARE, alla NGOs inriktade på humanitära insatser, samt FN och den pakistanska staten. Vi framlägger i vår studie teorin att ett effektivt samarbete främst kan komma till stånd om de

Syftet med uppsatsen är att skapa ett teoretiskt kunskapsbidrag där vi identifierar och kartlägger hur de olika litteraturområdena sammanfaller och samverkar i avseendet värdebildande aspekter inom ett industriellt nätverk. Studiens syfte är även att bringa klarhet i huruvida Sölvesborgsregionens fiskoljeprojekt är möjligt att genomföra samt att definiera eventuella hinder. Uppsatsen har två separ

Vart fjärde år väljer vi de politiker vi anser bäst kan tillgodose våra behov och önskemål. Politikerna antar mål för den offentliga verksamheten som förhoppningsvis motsvarar det väljarna förväntar sig. Men vad händer sedan? Arbetet behandlar hur väl implementeringen av politiskt antagna styrdokument fungerar, från politikerna, via tjänstemännen och ut till privata entreprenörer. Vi har valt att