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A β-mannosidase was purified to homogeneity from the culture filtrate of Aspergillus niger. A specific activity of 500 nkat mg−1 and a 53-fold purification was achieved using ammonium sulfate precipitation, anion-exchange chromatography, and gel filtration. The isolated enzyme has an isoelectric point of 5.0 and appears to be a dimer composed of two 135-kDa subunits. It is a glycoprotein and conta
Popular Abstract in Swedish Allmän Introduktion Hormonkänsligt lipas (HKL/HSL) är det protein (enzym) som hydrolyserar (bryter ner) det fett som finns lagrat inne i fettcellerna i fettväven. HSL finns också i steroidproducerande vävnader, som t.ex. binjure, äggstockar, moderkaka och testikel, och har troligtvis en viktig funktion i steroidsyntesen i åtminstone vissa av dessa vävnader. Det är dock Hormone-sensitive lipase (HSL) is a key enzyme in adipose tissue that hydrolyses stored fat (triacylglycerol). The activity of HSL is under strict hormonal and neural control. Lipolytic agents, such as catecholamines, increase the cAMP levels, resulting in an activation of cAMP-dependent protein kinase (PKA), which in turn phosphorylates and activates HSL. This thesis describes the structural orga
The purpose of this study is to dissect the process of ideological orientation in the public debate of postwar Sweden. Crucial to the study is the idea of a generic totalitarianism; a concept used both on a scholarly and a political level, focusing on the similarities between communism and Nazism, and the diverging guiding potential of this totalitarianism idea in different times and situations.
Popular Abstract in Swedish Bakgrund I Sverige erbjuds samtliga gravida kvinnor ett rutinultraljud vid 18-20 graviditetsveckor. Syftet med undersökningen är att fastställa antalet foster, uppskatta graviditetslängd samt granska fosteranatomin för att upptäcka eventuella missbildningar. En del missbildningar kan man se med ultraljud, men långtifrån alla. Att redan under graviditeten känna till om The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. Prenatal diagnosis of major congenital heart malformations was compared between the two groups. In
The first aim of this study was to on historical background survey women's alcohol habits and especially to investigate women aged 50-59 living in the Lund area. The second aim was to increase the understanding of how women's sex role has a restrictive influence on their alcohol habits. To investigate women's alcohol habits I made two quantitative studies. From secondary data I found t
Inte bara potthål och andra korta gupp, utan även mycket långa ojämnheter på vägbanan skapar stora dynamiska laster då tunga fordon färdas där. Dessa laster skadar vägbanan och gör att slitaget ökar så att livslängden på vägbanan förkortas. Detta leder i sin tur till att kostnaden för att hålla vägbanan i acceptabelt skick ökar. Syftet med detta examensarbete är pröva en metod för att beräkna och
Blåljusutredningen tillsattes med syftet att stärka det straffrättsliga skyddet för blåljuspersonal och andra samhällsnyttiga funktioner. Bakgrunden var förekomsten av stenkastning och våld mot blåljuspersonal (polis, ambulans och räddningstjänst) under uttryckningar, ett fenomen som är mest uttalat i socioekonomiskt svagare förorter. Dessutom påverkades utredningen av medias rapporteringar av hurBlåljusutredningen was appointed with the aim to strengthen the criminal law protection of the police, ambulance, rescue service and other professions related to public service. The background was the occurrence of violence against the police in Swedish socio-economically weakened suburbs. In addition, Blåljusutredningen was affected by the medial news coverage of how staff on emergency hospitals
This thesis addresses the lack of consideration of Instagram as an online brand community. The aim is to explore consumption activities and motives regarding the artisan food brand on Instagram. It also seeks to investigate the idea of craft products and its influence on consumers' consumption choices and activities, including the concept of craft consumption. A netnographic approach is the ma
Objective: The objective was to investigate the association between experience of violation during the past 3 months and self-rated health, taking trust (social capital), economic stress, and country of birth and parents' country of birth into account. Design/setting/participants/measurements: The 2008 public health survey in Skåne is a cross-sectional study with 55% response rate. A random sample
This thesis deals with the task of modeling a web server and designing a mechanism that can prevent the web server from being overloaded. Four papers are presented. The first paper gives an M/G/1/K processor sharing model of a single web server. The model is validated against measurements ands imulations on the commonly usedw eb server Apache. A description is given on how to calculate the necessar
As the way of communicating and accessing information has changed radically over the past decade so has the way the public libraries operate to reach the citizens. In these times the demands of what a public library should be and offer the visitors have changed. One should have the option to access the digital public library at any given hour of the day, from anywhere in the world and at least
The aim of this study was to examine the view of social service workers on the secondary housing market based upon their work with social investigations regarding people with a difficult substance abuse. The foundation of this study rests upon a phenomenon, which according to other scholars, occurs in the secondary housing market in Sweden. The secondary housing market consists of a multitude of h
The web is a constantly growing medium that presumably plays an increasing role in public library reference services. In order to provide high quality reference service the librarians need to be able to master this medium. Therefore it is interesting to get an understanding of how librarians actually use the web. The aim of this Master s thesis is to investigate what web search tools are used by p
This paper summarized the efforts performed to understand decay heat estimation from existing spent nuclear fuel (SNF), under the auspices of the Working Party on Nuclear Criticality Safety (WPNCS) of the OECD Nuclear Energy Agency. Needs for precise estimations are related to safety, cost, and optimization of SNF handling, storage, and repository. The physical origins of decay heat (a more correc
Mot bakgrund av ett mer osäkert geopolitiskt omvärldsläge, ökad digitalisering och klimatrelaterade risker har frågor om energisystemens försörjningsberedskap fått ökad betydelse. Fjärrvärme utgör en samhällskritisk funktion av svensk energiförsörjning och spelar en central roll i klimatomställningen, samtidigt som systemen präglas av tekniska beroenden, komplexa leverantörskedjor och organisatoriAgainst the backdrop of an increasingly uncertain geopolitical environment, growing digitalization, and climate-related risks, issues concerning the security of energy supply have gained greater importance. District heating constitutes a critical societal function within Sweden’s energy system and plays a central role in the climate transition. At the same time, district heating systems are charac
Background: Despite improvements in surgical methodologies and perioperative chemo- and radiotherapy, the prognosis for patients with esophageal and gastric cancer remains poor. Hence, there is a great need to identify complementary biomarkers for improved treatment stratification. Tumor-infiltrating immune cells have been shown to impact on outcome in many types of cancer, including gastroesophag
INTRODUCTION: Opioid use disorder (OUD) is the leading cause of overdose morbidity and mortality globally. Retention in opioid agonist treatment (OAT) is crucial as it effectively reduces overdose mortality among individuals suffering from OUD. Previous research on treatment retention among heroin-dependent individuals referred from needle exchange programs (NEP) to OAT is scarce, and with predict
When does the mind begin? Infant psychology is mysterious in part because we cannot remember our first months of life, nor can we directly communicate with infants. Even more speculative is the possibility of mental life prior to birth. The question of when consciousness, or subjective experience, begins in human development thus remains incompletely answered, though boundaries can be set using cu
The distance of sprinklers below ceiling is of fundamental importance since it has a great influence on activation time. Accepted distances are specified in different sprinkler standards such as NFPA 13, FM 2-0 and EN 12845 for different configurations. This distance is unambiguously defined for flat smooth ceilings, but for corrugated ceilings, such as corrugated metal deck ceilings found in many
