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Background Gadolinium (Gd) neutron capture therapy (GdNCT) is based on a neutron capture reaction (NCR) that involves emission of both short and long range products. The aim of this study was to investigate both the microscopic and macroscopic contributions of the absorbed dose involved in GdNCT. Methods Cylindrical containers with diameters 1-30 mm filled with a solution of Gd were irradiated wit
Recent reports suggested frequent occurrence of cancer associated somatic mutations within regulatory elements of the genome. Based on initial exome sequencing of 21 melanomas, we report frequent somatic mutations in skin cancers in a bidirectional promoter of diphthamide biosynthesis 3 (DPH3) and oxidoreductase NAD-binding domain containing 1 (OXNAD1) genes. The UV-signature mutations occurred at
Humanity injects an almost incomprehensible 42 billion tonnes of carbon dioxide (CO₂) into the atmosphere every year. The majority of this comes from burning fossil fuels, but a substantial portion, about 16%, arises from how we use the land. Most of these land-use emissions are caused by deforestation, particularly in the tropics.In order to slow climate change, the global community needs to redu
This article discusses the relationship between undocumentedness, informality, and vulnerability to crime among migrants, using the strain theory as a conceptual framework. Research on victimisation and engagement in crime among migrants is limited, and existing studies tend to focus on one aspect rather than the interplay between the two. This study focuses on the experiences of the Uzbek communi
PurposeThe aim was to explore factors affecting guideline adherence among doctors in the emergency department and to explore the general perception about local guidelines for traumatic brain injuries.MethodsThirty semi-structured interviews were conducted with doctors with experience working in the emergency department regarding different aspects of guideline use, with emphasis on the management o
Automated decision-making (ADM) has been introduced into the public sector in many countries, including for decisions made regarding the provision of economic support to people in need. This article analyses the value positions (the ‘desired intentions’) for using ADM to determine such decisions in four Swedish municipalities. The value positions related to efficiency of the application process, i
BackgroundMizoram has the highest incidence of cancer in India. Among women, breast cancer is most prevalent and the state occupies fifth position globally. The reason for high rate of cancer in this region is still not known but it may be related to ethnic/racial variations or lifestyle factors.MethodsThe present study aims to identify the candidate mitochondrial DNA (mtDNA) biomarkers—ND1and ATP
Background: Assessment of the quality of life (QoL) among healthcare workers (HCWs) is vital for better healthcare and is an essential indicator for competent health service delivery. Since the coronavirus disease 2019 (COVID-19) pandemic strike, the frontline position of HCWs subjected them to tremendous mental and psychological burden with a high risk of virus acquisition. Aim: This study evalua
Purpose: The aim of this study was to explore how women experienced sexuality after radical cystectomy due to bladder cancer. Methods: We performed an interview study with qualitative design with content analysis. Inclusion criteria were age below 75 years. In total 10 women, with a median age of 64 years at surgery, were interviewed at median 24 months post radical cystectomy. Results: The 10 wom
Aims Among patients with acute coronary syndromes (ACS), those with diabetes mellitus (DM) are at particularly high risk of recurrent cardiovascular events and premature death. We aimed to provide a descriptive overview of unadjusted analyses of patient characteristics, ACS management, and outcomes up to 1 year after hospital admission for an ACS/index-ACS event, in patients with DM in contemporar
Objectives In an acute heart failure (AHF) setting, proenkephalin A 119-159 (penKid) has emerged as a promising prognostic marker for predicting worsening renal function (WRF), while bioactive adrenomedullin (bio-ADM) has been proposed as a potential marker for congestion. We examined the diagnostic value of bio-ADM in congestion and penKid in WRF and investigated the prognostic value of bio-ADM a
Hur stor bör den svenska statsskulden vara? I dag finns en livlig debatt kring frågan, knuten till överskottsmålets vara eller inte vara. Den ekonomiska litteraturen ger inget klart svar. Storleken på den ”optimala” eller lämpliga statsskulden beror på både vilken teori eller riktlinje som är utgångspunkten och vilken empirisk metod som används. Vi argumenterar för att statsskulden mätt som Maast
Background: Hypertrophic cardiomyopathy (HCM) is the most common monogenic cardiac disorder and the leading cause of sudden cardiac death in the young. Although in a majority of HCM cases there are gene mutations coding for sarcomere proteins, the onset for the clinical consequences of these mutations are difficult to predict, as these mutations do not show any clear relationship to the degree of
Adolescents have a unique developmental vulnerability to suicide, with youth presenting as the second most vulnerable group to suicide across the lifespan. Youth have been recognized as underserved mental health service recipients, with only one in six of those in need receiving care. Calls for innovative mental health services to better serve youth have been articulated for over a decade and the
This collection gathers the more important instruments dealing with the relationships of business with a range of topics such as labor rights, security issues, environmental protection, anti-corruption, good governance, poverty alleviation and development, which all have important human rights dimensions. The premise for this selection is that business has both responsibilities and opportunities t
Bearing a child and giving birth are often considered as a life-changing event in the life of a woman and her family, a source of joy and fulfillment. But in spite of the progress achieved in the last century, every two minutes one woman still dies from pregnancy or childbirth related causes (WHO 2018). All too often, becoming a mother can be associated with pain, suffering and even distress, disa
Popular science summary To Migrate or Not to Migrate! An interesting experiment to test how gender, personality traits, size, and condition affect migration in Roach (Rutilus rutilus). Partial migration is a phenomena in which migration does not take place in every individual’s lifecycle. The reason for this type of migration has not yet been totally understood. However, there has been studies
Sammanfattning Titel: Chefens stöd i relationen till sina medarbetare: en studie kring hur stöd för frontpersonal upplevs genom relationen mellan frontpersonal och deras chefer Universitet: Lunds Universitet, Campus Helsingborg, Institutionen för Service Management Kurs: KSKK01, Service Management: Examensarbete för kandidatexamen, 15 hp, VT2013 Författare: Sofie Fredriksson & Sara Thorén Han
