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Epidemiology, bacteriology, and clinical characteristics of HACEK bacteremia and endocarditis : a population-based retrospective study

The objective was to describe the epidemiology, bacteriology, clinical presentation, risk factors for endocarditis (IE), diagnostic workup, and outcome of patients with bacteremia caused by the non-influenzae Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, and Kingella genera (HACEK). A retrospective population-based cohort of patients with bacteremia collected from 2012 to 2017 was iden

Individuell Mätning och Debitering av komfortvärme och varmvatten

EU’s and the Swedish government’s requirements to lower the energy consumption for buildings are getting stricter. In April 30 2014 the law on energy metering (SFS 2014: 267) was issued. The law deals with energy metering in new construction and reconstruction, during 2015 a decision must be taken on how measurement in existing buildings should be handled. Individual metering and charging (IMC) co

Ett självklart offer? En intervjustudie av myndigheters samverkan gällande barn som bevittnat våld i nära relation

Denna studie undersöker samverkansprocessen mellan Socialtjänst, Polis- och Åklagarmyndighet i deras arbete med barn som bevittnat våld i nära relationer. Syftet är att skildra och problematisera samverkan beträffande barn som bevittnat våld och deras eventuella möjlighet till att uppnå status som offer. Även kvinnojourers uppfattning om myndigheternas arbete har undersökts. Materialet omfattar sjThis study examines the process of cooperation between The Social service, Police department/authority and The Prosecution authority in Sweden in their work with children who have witnessed domestic violence. The purpose is to explore and to problematize if there are any difficulties concerning the cooperation between these authorities. Also the women shelters’ perception of the authorities work i

Patients with ankylosing spondylitis have increased sick leavea registry-based casecontrol study over 7 yrs

Objectives. Using prospectively collected registry data to investigate sick leave (sickness benefit and sickness compensation) over a 7-yr period in patients with AS in comparison with population-based controls matched for age, sex and residential area. Methods. We investigated 122 (21 women and 101 men) outpatients with AS in South Sweden, born 1942 or later, from rheumatology specialist care for

Unlock my potential! - en uppsats om hur projektledare kan frigöra och ta tillvara individers kreativitet för att främja serviceorganisationers innovationsförmåga

Titel: Unlock my potential! – en uppsats om hur projektledare kan frigöra och ta tillvara individers kreativitet för att främja serviceorganisationers innovationsförmåga Universitet: Lunds Universitet, Campus Helsingborg, Institutionen för Service Management Kurs: SMTX07 Service Management: Examensarbete – Magisterkurs, 15hp, VT 2010 Seminariedatum: 1 juni 2010 Författare: Kristin Lagerström och C

Coming out in Copenhagen. Homo Sports Events in City Marketing

The intense competition between places means that new and more differentiated marketing strategies are becoming increasingly important in order to attract visitors and other target groups. In order to be seen, gain positive media attention and put the place on the map many cities try to develop marketing concepts based on experiences, among other things. One such strategy used by many places is to

Cardiac Natriuretic Peptides, Obesity, and Insulin Resistance: Evidence from Two Community-Based Studies.

Background: The natriuretic peptides play an important role in salt homeostasis and blood pressure regulation. It has been suggested that obesity promotes a relative natriuretic peptide deficiency, but this has been a variable finding in prior studies and the cause is unknown. Aim: The aim of this study was to examine the association between obesity and natriuretic peptide levels and evaluate the

Assessment of gene-by-sex interaction effect on bone mineral density

Sexual dimorphism in various bone phenotypes, including bone mineral density (BMD), is widely observed; however, the extent to which genes explain these sex differences is unclear. To identify variants with different effects by sex, we examined gene-by-sex autosomal interactions genome-wide, and performed expression quantitative trait loci (eQTL) analysis and bioinformatics network analysis. We co

Podoplanin Is a Useful Marker for Identifying Mesothelioma in Malignant Effusions

The diagnosis of malignant mesothelioma in serosal effusions continues to he a major challenge because some of its cytomorphological features closely resemble adenocarcinomas. Immunohistochemistry is a valuable tool in the differentiation of epithelioid mesothelioma from metastatic adenocarcinomas. However, no single antibody has demonstrated absolute sensitivity or specificity. In this study, we

Preterm birth and risk of epilepsy in Swedish adults

Objective: To determine whether preterm birth is associated with epilepsy in a national cohort of adults aged 25-37 years. Methods: We conducted a national cohort study of 630,090 infants born in Sweden from 1973 through 1979, including 27,953 born preterm (< 37 weeks), followed from 2005 to 2009 for 1) hospitalization for epilepsy and 2) outpatient and inpatient prescription of antiepileptic drug

Performance in physical education and health impairment 30 years later-a community based cohort study.

OBJECTIVE: A main purpose of physical education (PE) in school is to promote future health. However, there is very limited evidence of the effects of PE on the adult health. We hypothesized that a low performance in PE was associated with an increased risk of health impairment by middle age. METHODS: We performed a cohort study in a community-based setting in Sweden spanning over three decades. W

Transcriptional regulation of HIF-2α in neuroblastoma

Popular science summary: Transcriptional regulation of HIF-2α in neuroblastoma Neuroblastoma is the most common solid tumor in childhood. The presence of hypoxia -regions of low levels of oxygen- causes a more immature tumor phenotype that is related to a more aggressive form of this cancer. Hypoxia is mainly directed by Hypoxia Inducible Factors (HIF)-1α and HIF-2α. High levels of HIF-2α expre

Conditioning demand : Older people, thermal comfort and low-carbon housing

This special issue presents findings from the ‘Conditioning Demand: Older People, Diversity, and Thermal Experience’ re- search project undertaken between 2011 and 2013. The aim of the project was to address the confluence of two key future trends: Europe's ageing population and the need to reduce domestic en- ergy consumption to counter rising utility prices and the in- creasing threat of climate

The 10-year incidence of hypertension across blood pressure categories in a population-based cohort in southwestern Sweden

Background: To explore the determinants of incident hypertension, and especially the impact of baseline blood pressure categories, in a representative Swedish population. Methods: A 10-year longitudinal study of residents aged 30–74. Blood pressures were measured and categorized according to ESH guidelines with optimal blood pressure < 120/80 mmHg, normal 120–129/80–84 mmHg, and high normal 130–13

Risk of Major Bleeding in Patients With Atrial Fibrillation Taking Dronedarone in Combination With a Direct Acting Oral Anticoagulant (From a U.S. Claims Database)

Dronedarone may increase exposure and the risk of major bleeding when prescribed with a direct oral anticoagulant (DOAC). This retrospective cohort study examined the risk of the first occurrence of major bleeding (hospitalization or emergency room visit for gastrointestinal [GI] bleeding, intracranial hemorrhage [ICH], or bleeding at other sites) among new users of apixaban, dabigatran, and rivar

Circumferential resection margin is a predictor for metastatic disease after rectal cancer surgery: a nation-wide population-based study cohort

Background/Aim To evaluate circumferential resection margin(CRM) as a risk factor for distant metastasis (DM) in rectal cancer.The treatment of rectal cancer has evolved over the last decades.Surgical radicality is the single most important factor in preventingrecurrences, both locally and distantly. CRM B 1.0 mm is consideredto increase recurrence risk. However, not all patients with CRMB 1.0 mm

Cumulative incidence of ureteroenteric strictures after radical cystectomy in a population-based Swedish cohort

Objective: The incidence of benign ureteroenteric strictures following radical cystectomy (RC) for urinary bladder cancer (UBC) is investigated mainly in single-centre studies from high-volume centres. The aim of this study was to evaluate the cumulative incidence of strictures and risk factors in a population-based cohort. Patients and methods: Data was collected from Bladder Cancer Data Base Swe

Lynch syndrome-associated epithelial ovarian cancer and its immunological profile

Introduction: Lynch syndrome is a multi-tumor syndrome characterized by mismatch repair deficiency (MMR-d), microsatellite instability (MSI), and increased tumor-infiltrating lymphocytes (TILs) making these tumors candidates for treatment with immune checkpoint inhibitors. However, response may depend on tumor-induced immune evasion mechanisms, e.g. loss of Beta-2-Microglobulin (B2M) or upregulati

Are structural abnormalities on knee MRI associated with osteophyte development? Data from the Osteoarthritis Initiative

Objective: To assess which structural abnormalities on knee MRI are associated with development of osteophytes in middle-aged subjects without radiographic knee osteoarthritis. Design: We included subjects from the Osteoarthritis Initiative, aged 40–55 years, Kellgren & Lawrence grade 0 in both knees, and knee MRIs from both knees available at baseline, 24, 48 and 72 months. Structural exposur