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Challenging the dogma of colorectal peritoneal metastases as an untreatable condition : Results of a population-based study

PURPOSE: To determine the impact of the implementation of novel systemic regimens and locoregional treatment modalities on survival at population level in colorectal cancer (CRC) patients presenting with peritoneal metastases (PMs).METHODS: All consecutive CRC patients with synchronous PM (<3 months) between 1995 and 2014 were extracted from the Eindhoven area of the Netherlands Cancer Registry. T

Randomized trial of cytoreduction and hyperthermic intraperitoneal chemotherapy versus systemic chemotherapy and palliative surgery in patients with peritoneal carcinomatosis of colorectal cancer

PURPOSE: To confirm the findings from uncontrolled studies that aggressive cytoreduction in combination with hyperthermic intraperitoneal chemotherapy (HIPEC) is superior to standard treatment in patients with peritoneal carcinomatosis of colorectal cancer origin.PATIENTS AND METHODS: Between February 1998 and August 2001, 105 patients were randomly assigned to receive either standard treatment co

Quality assessment of radiotherapy in the prospective randomized SENOMAC trial

Background and purpose: Recommendations for regional radiotherapy (RT) of sentinel lymph node (SLN)-positive breast cancer are debated. We here report a RT quality assessment of the SENOMAC trial. Materials and Methods: The SENOMAC trial randomized clinically node-negative breast cancer patients with 1–2 SLN macrometastases to completion axillary lymph node dissection (cALND) or SLN biopsy only be

MiDAS 5 : Global diversity of bacteria and archaea in anaerobic digesters

Anaerobic digestion of organic waste into methane and carbon dioxide (biogas) is carried out by complex microbial communities. Here, we use full-length 16S rRNA gene sequencing of 285 full-scale anaerobic digesters (ADs) to expand our knowledge about diversity and function of the bacteria and archaea in ADs worldwide. The sequences are processed into full-length 16S rRNA amplicon sequence variants

The role of echocardiography in sports cardiology : An expert opinion statement of the Italian Society of Sports Cardiology (SIC sport)

Transthoracic echocardiography (TTE) is routinely required during pre-participation screening in the presence of symptoms, family history of sudden cardiac death or cardiomyopathies <40-year-old, murmurs, abnormal ECG findings or in the follow-up of athletes with a history of cardiovascular disease (CVD). TTE is a cost-effective first-line imaging modality to evaluate the cardiac remodeling due to

A temporal developmental map separates human NK cells from noncytotoxic ILCs through clonal and single-cell analysis

Natural killer (NK) cells represent the cytotoxic member within the innate lymphoid cell (ILC) family that are important against viral infections and cancer. Although the NK cell emergence from hematopoietic stem and progenitor cells through multiple intermediate stages and the underlying regulatory gene network has been extensively studied in mice, this process is not well characterized in humans

Hybrid speciation driven by multilocus introgression of ecological traits

Hybridization allows adaptations to be shared among lineages and may trigger the evolution of new species1,2. However, convincing examples of homoploid hybrid speciation remain rare because it is challenging to demonstrate that hybridization was crucial in generating reproductive isolation3. Here we combine population genomic analysis with quantitative trait locus mapping of species-specific trait

No title

This Bachelor’s thesis examines the ever-changing educational role of the museum in our society. With a specific focus on the ethnographic museum, especially the Danish National museum’s ethnographic collection, I will try to illustrate the constant discussions on the topic of how one in the best way can represent or create exhibitions in the present day. Today people have an image of museum curat

Age and diagnostic performance of Alzheimer disease CSF biomarkers

Objectives: Core CSF changes in Alzheimer disease (AD) are decreased amyloid beta(1-42), increased total tau, and increased phospho-tau, probably indicating amyloid plaque accumulation, axonal degeneration, and tangle pathology, respectively. These biomarkers identify AD already at the predementia stage, but their diagnostic performance might be affected by age-dependent increase of AD-type brain

F-18-fluorodeoxyglucose-positron emission tomography/computed tomography after one cycle of chemotherapy in patients with diffuse large B-cell lymphoma: results of a Nordic/US intergroup study

We evaluated the predictive value of interim positon emission tomography (I-PET) after one course of chemoimmunotherapy in patients with newly diagnosed diffuse large B-cell lymphoma (DLBCL). One hundred and twelve patients with DLBCL were enrolled. All patients had PET/computed tomography (CT) scans performed after one course of chemotherapy (PET-1). I-PET scans were categorized according to Inte

Dynamic Interference of Chirped Photoelectrons

Dynamic interference is an elusive strong-field effect where photoelectrons from intense laser pulses interfere in time, forming rich kinetic energy patterns. Here, we present the first experimental demonstration of isolated dynamic interference using a novel two-color scheme: chirped laser-assisted dynamic interference. Isolation was achieved with a crossed-polarization setup combining an extreme

Biocompatibility of two model elastin-like recombinamer-based hydrogels formed through physical or chemical cross-linking for various applications in tissue engineering and regenerative medicine

Biocompatibility studies, especially innate immunity induction, in vitro and in vivo cytotoxicity, and fibrosis, are often lacking for many novel biomaterials including recombinant protein-based ones, such as elastin-like recombinamers (ELRs), and has not been extensively explored in the scientific literature, in contrast to traditional biomaterials. Herein, we present the results from a set of ex

Luminosity measurement at ATLAS - Development, construction and test of scintillating fibre prototype detectors

We are reporting about a scintillating fibre tracking detector which is proposed for the precise determination of the absolute luminosity of the CERN LHC at interaction point 1 where the ATLAS experiment is located. The detector needs to track protons elastically scattered under mu rad angles in direct vicinity to the LHC beam. It is based on square shaped scintillating plastic fibres read out by

Transferability of tag SNPs in genetic association studies in multiple populations

A general question for linkage disequilibrium-based association studies is how power to detect an association is compromised when tag SNPs are chosen from data in one population sample and then deployed in another sample. Specifically, it is important to know how well tags picked from the HapMap DNA samples capture the variation in other samples. To address this, we collected dense data uniformly

The West African climate system: a review of the AMMA model inter-comparison initiatives

We review the African Monsoon Multidisciplinary Analysis (AMMA) model inter-comparison activities for West Africa. The Model Inter-comparison Project is an evaluation exercise of how global and regional atmospheric models represent seasonal and intra-seasonal variations of the climate and rainfall over the Sahel. The Land surface Model Inter-comparison Project in turn focuses on modelling critical

Terms, definitions and measurements to describe sonographic features of myometrium and uterine masses: a consensus opinion from the Morphological Uterus Sonographic Assessment (MUSA) group

The MUSA (Morphological Uterus Sonographic Assessment) statement is a consensus statement on terms, definitions and measurements that may be used to describe and report the sonographic features of the myometrium using gray-scale sonography, color/power Doppler and three-dimensional ultrasound imaging. The terms and definitions described may form the basis for prospective studies to predict the ris

Wp 12 may 2012 0

Social sector auditing –From soft to sharp auditing RESEARCH IN SERVICE STUDIES Working paper No 12, May 2012 The Department of Service Management Campus Helsingborg | Lund University Emma Ek, School of Public Administration, Gothenburg University Gustaf Kastberg, Department of Service Management, Lund University 1 2 Social sector auditing – From soft to sharp auditing Emma Ek, School of public ad

https://www.ses.lu.se/sites/ses.lu.se/files/wp_12_may_2012_0.pdf - 2026-05-07

ATMP Pipeline Report 2024 092024 final

ATMP Pipeline Report 2024_092024_final draft_PM & Bleed_2.0 A look at how the cell and gene therapy field from the local level to the national stage. is developing in Sweden, THE ATMP PIPELINE REPORT LUND STEM CELL CENTER | LUND UNIVERSITY ATMP CENTER | LUND UNIVERSITY NR 2 | 2024 What’s on the ATMP horizon? 4 QUOUSQUE TANDEM ABUTERE 3QUOUSQUE TANDEM ABUTERE CONTENTS A Quick Look at the Report 4 C

https://www.stemcellcenter.lu.se/sites/stemcellcenter.lu.se/files/2024-11/ATMP%20Pipeline%20Report%202024_092024_final.pdf - 2026-05-07

Microsoft PowerPoint - Posterlund.ppt

Microsoft PowerPoint - Posterlund.ppt INTRODUCTION Morpho-syntactic context effects in spoken language : An ERP study Angèle Brunellière and Ulrich Hans Frauenfelder Laboratory of experimental psycholinguistics, University of Geneva METHOD RESULTS RESULTS CONCLUSIONS References Kutas, M. and Hillyard SA. (1984) Brain potentials during reading reflect word expectancy and semantic associaton. Nature

https://konferens.ht.lu.se/fileadmin/user_upload/sol/ovrigt/konferens_BrainTalk/Brunelliere.pdf - 2026-05-04