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Impact of thearubigins on the estimation of total dietary flavonoids in the European Prospective Investigation into Cancer and Nutrition (EPIC) study

Thearubigins (TR) are polymeric flavanol-derived compounds formed during the fermentation of tea leaves. Comprising similar to 70% of total polyphenols in black tea, TR may contribute majorly to its beneficial effects on health. To date, there is no appropriate food composition data on TR, although several studies have used data from the US Department of Agriculture (USDA) database to estimate TR

Confirmation of TNIP1 but not RHOB and PSORS1C1 as systemic sclerosis risk factors in a large independent replication study

Introduction A recent genome-wide association study in European systemic sclerosis (SSc) patients identified three loci (PSORS1C1, TNIP1 and RHOB) as novel genetic risk factors for the disease. The aim of this study was to replicate the previously mentioned findings in a large multicentre independent SSc cohort of Caucasian ancestry. Methods 4389 SSc patients and 7611 healthy controls from differe

Plasma Elaidic Acid Level as Biomarker of Industrial Trans Fatty Acids and Risk of Weight Change: Report from the EPIC Study.

Few epidemiological studies have examined the association between dietary trans fatty acids and weight gain, and the evidence remains inconsistent. The main objective of the study was to investigate the prospective association between biomarker of industrial trans fatty acids and change in weight within the large study European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.

Coulomb excitation of Ga-73

The B(E2; I-i -> I-f) values for transitions in Ga-71(31)40 and Ga-73(31)42 were deduced from a Coulomb excitation experiment at the safe energy of 2.95 MeV/nucleon using post-accelerated beams of Ga-71,Ga-73 at the REX-ISOLDE on-line isotope mass separator facility. The emitted gamma rays were detected by the MINIBALL gamma-detector array, and B(E2; I-i -> I-f) values were obtained from the yield

International Epidemiology of Child and Adolescent Psychopathology II: Integration and Applications of Dimensional Findings From 44 Societies

Objective: To build on Achenbach, Rescorla, and Ivanova (2012) by (a) reporting new international findings for parent, teacher, and self-ratings on the Child Behavior Checklist, Youth Self-Report, and Teacher's Report Form; (b) testing the fit of syndrome models to new data from 17 societies, including previously underrepresented regions; (c) testing effects of society gender, and age in 44 societ

The Gaia-ESO Survey: CNO abundances in the open clusters Trumpler 20, NGC 4815, and NGC 6705

Context. The Gaia-ESO Public Spectroscopic Survey will observe a large sample of clusters and cluster stars, covering a wide age-distance-metallicity-position-density parameter space. Aims. We aim to determine C, N, and O abundances in stars of Galactic open clusters of the Gaia-ESO survey and to compare the observed abundances with those predicted by current stellar and Galactic evolution models.

Isospin Symmetry in the sd Shell: Transition Strengths in the Neutron-deficient sd Shell Nucleus 33Ar

Reduced transition strengths of the deexciting transitions from the first two excited states in 33Ar were measured in a relativistic Coulomb excitation experiment at the GSI Helmholtz center. The radioactive ion beam was produced by fragmentation of a primary 36Ar beam on a 9Be target followed by the selection of the reaction product of interest via the GSI Fragment Separator. The 33Ar beam hit a

Gaia-ESO Survey: Properties of the intermediate age open cluster NGC 4815

Context. NGC 4815 is a populous similar to 500 Myr open cluster at R-gc similar to 7 kpc observed in the first six months of the Gaia-ESO Survey. Located in the inner Galactic disk, NGC 4815 is an important potential tracer of the abundance gradient, where relatively few intermediate age open clusters are found. Aims. The Gaia-ESO Survey data can provide an improved characterization of the cluster

Subtypes of fruit and vegetables, variety in consumption and risk of colon and rectal cancer in the European Prospective Investigation into Cancer and Nutrition.

Previously, a lower risk of colorectal cancer was observed with fruit and vegetable consumption in the European Prospective Investigation into Cancer and Nutrition within a follow-up period of nine years which was not fully supported by a recent meta-analysis. Therefore, we were interested in the relation with extended follow-up, also focusing on single subtypes and variety of intake of fruit and

Common Carotid Intima-Media Thickness Relates to Cardiovascular Events in Adults Aged

Although atherosclerosis starts in early life, evidence on risk factors and atherosclerosis in individuals aged <45 years is scarce. Therefore, we studied the relationship between risk factors, common carotid intima-media thickness (CIMT), and first-time cardiovascular events in adults aged <45 years. Our study population consisted of 3067 adults aged <45 years free from symptomatic cardiovascular

Addressing Challenges in Simulating Inter–Annual Variability of Gross Primary Production

A long-standing challenge in studying the global carbon cycle has been understanding the factors controlling inter–annual variation (IAV) of carbon fluxes, and improving their representations in existing biogeochemical models. Here, we compared an optimality-based model and a semi-empirical light use efficiency model to understand how current models can be improved to simulate IAV of gross primary

Binarity at LOw Metallicity (BLOeM) Enhanced multiplicity of early B-type dwarfs and giants at Z = 0.2 Z

Early B-type stars with initial masses between 8 and 15 M are frequently found in multiple systems, as is evidenced by multi-epoch spectroscopic campaigns in the Milky Way and the Large Magellanic Cloud (LMC). Previous studies have shown no strong metallicity dependence in the close-binary (a < 10 au) fraction or orbital-period distributions between the Milky Way’s solar metallicity (Z) and that o

Pain management in preterm infants with necrotizing enterocolitis : an international expert consensus statement

Necrotizing enterocolitis (NEC) is probably the most painful intestinal disease affecting infants born preterm. NEC is known to cause highly severe and prolonged pain that has been associated with adverse short- and long-term effects. However, research on pain management in infants with NEC is scarce. This is likely due to its low incidence and very acute occurrence. As a result, the optimal pain

The design and performance of the Gaia photometric system

The European Gaia astrometry mission is due for launch in 2011. Gaia will rely on the proven principles of the ESA Hipparcos mission to create an all-sky survey of about one billion stars throughout our Galaxy and beyond, by observing all objects down to 20 mag. Through its massive measurement of stellar distances, motions and multicolour photometry, it will provide fundamental data necessary for

Eating out of home and its correlates in 10 European countries. The European Prospective Investigation into Cancer and Nutrition (EPIC) study

OBJECTIVE: To compare the average out-of-home (OH) consumption of foods and beverages, as well as energy intake, among populations from 10 European countries and to describe the characteristics of substantial OH eaters, as defined for the purpose of the present study, in comparison to other individuals. DESIGN: Cross-sectional study. Dietary data were collected through single 24-hour dietary recal

Isomers in neutron-rich A approximate to 190 nuclides from Pb-208 fragmentation

Relativistic projectile fragmentation of Pb-208 has been used to produce isomers in neutron-rich, A approximate to 190 nuclides. A forward-focusing spectrometer provided ion-by-ion mass and charge identification. The detection of gamma-rays emitted by stopped ions has led to the assignment of isomers in Ta-188, W-190, Re-192, Re-193, Os-195, Ir-197, Ir-198, Pt-200, Pt-201, Pt-202 and Au-203, with

Investigations of neutron deficient nuclei close to Sn-100 with EUROBALL

Excited states of nuclei in the vicinity of Sn-100 have been studied using: the EUROBALL detector array. Gamma-ray lines from Sn-103 have been identified for the first time, and a level scheme of low-lying excited states of Sn-103 has been established. New constraints on energies of single particle orbitals with respect to the Sn-100 core are obtained.