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Data analysis tools for uncertainty quantification of inverse problems

We present exploratory data analysis methods to assess inversion estimates using examples based on l(2)- and l(1)-regularization. These methods can be used to reveal the presence of systematic errors such as bias and discretization effects, or to validate assumptions made on the statistical model used in the analysis. The methods include bounds on the performance of randomized estimators of a larg

Modeling the euglycemic hyperinsulinemic clamp by stochastic differential equations

The Euglycemic Hyperinsulinemic Clamp (EHC) is the most widely used experimental procedure for the determination of insulin sensitivity. In the present study, 16 subjects with BMI between 18.5 and 63.6 kg/m(2) have been studied with a long-duration (5 hours) EHC. In order to explain the oscillations of glycemia occurring in response to the hyperinsulinization and to the continuous glucose infusion

Assessing woody biomass in African tropical savannahs by multiscale remote sensing

Woody biomass production is a critical indicator in evaluation of land use management and the dynamics of the global carbon cycle (sequestration/emission) in terrestrial ecosystems. The objective of the present study was to develop, through a case study in Sudan, an operational multiscale remote-sensing-based methodology for large-scale estimation of woody biomass in tropical savannahs. Woody biom

Towards a Bioeconomy in Europe: National, Regional and Industrial Strategies

Establishing an advanced European bioeconomy is an important step in achieving the transition towards sustainable development and away from fossil fuels. The bioeconomy can be defined as an economy based on the sustainable production and conversion of renewable biomass into a range of bio-based products, chemicals, and energy. Several strategies have been produced in Europe from different perspect

Towards a molecular understanding of symbiont function: Identification of a fungal gene for the degradation of xylan in the fungus gardens of leaf-cutting ants

Background Leaf-cutting ants live in symbiosis with a fungus that they rear for food by providing it with live plant material. Until recently the fungus' main inferred function was to make otherwise inaccessible cell wall degradation products available to the ants, but new studies have shed doubt on this idea. To provide evidence for the cell wall degrading capacity of the attine ant symbiont, we

Formate dehydrogenase-modified carbon paste electrodes for amperometric detection of formate

A simple and inexpensive amperometric biosensor for formate detection was obtained by immobilization of for-mate dehydrogenase (FDH) on graphite powder, modified with a new phenothiazine derivative (DDDP; 16H, 18H-dibenzo[c,l]-7,9-dithia-16,18-diazapentacene). Two different enzyme environments were used: FDH was adsorbed on DDDP-modified graphite powder in the presence of polyethylenimine (PEI) as

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