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Stimuli-responsive polymers stand out for their ability to respond to small environmental changes. One of the most representative thermo-sensitive materials is poly(N-isopropyl acrylamide) (PNIPAm), which presents reversible phase transitions close to the human body temperature. However, previous studies observed that the copolymerization of NIPAm with small quantities of different monomers like a

Alzheimer’s Disease (AD), a neurodegenerative disease, defined by abnormal accumulation of proteins, both extracellularly (senile plaques, consisting of amyloid-beta(Aβ) accumulation) and intracellularly (neurofibrillary tangles, formed by Tau protein). Several studies demonstrate that the immune cells play a central role in the pathogenesis of AD, but it is not known if immune cells from the peri

In this paper, we explore contemporary regional development in a historic industrial region. Specifically, we unpack the influences of industrial history and culture, built up over several centuries, on contemporary regional development dynamics and issues. In doing so, we draw on an evolutionary perspective within economic geography and perspectives from deindustrialization studies to understand

Background and purpose: Pyruvate dehydrogenase complex deficiency is in up to 90% caused by pathogenic variants in the X-linked PDHA1 gene. We aimed to investigate female relatives of index patients with PDHA1-related disease to (i) describe the prevalence of female PDHA1 carriers, (ii) determine whether they had symptoms and signs, and (iii) delineate the associated phenotype. Methods: In a natio

In this introduction to the special issue on critical performativity and alternative organization we provide a brief historico-theoretical sketch of the key concepts involved and point to ongoing pertinent debates in the field of critical management studies. We also present the articles included in the issue, which all explore aspects of how critical performativity and alternative organization may

Gold (Au) and platinum (Pt) screen-printed electrodes were modified with Prussian Blue (PB) for the development of amperometric sensors selective for hydrogen peroxide detection. The sensors exhibited sensitivities towards H2O2 equal to 2 A M−1 cm−2 for Au and 1 A M−1 cm−2 for Pt electrodes. The sensors were also employed as the basis for construction of glucose biosensors through further modifica

In this work, we employ density functional theory to assign vibrational signatures of [FeFe]-hydrogenase intermediates to molecular structures. For this purpose, we perform an exhaustive analysis of structures and harmonic vibrations of a series of CN and CO containing model clusters of the [FeFe]-hydrogenase enzyme active site considering also different charges, counterions, and solvents. The pur

This perspective article explores how sustainability transitions experience a geo-economization based on rising concerns about sovereignty. We argue that sovereignty has yet again become an active force structuring socio-technical trajectories. In this case, socio-technical systems tend to be reconfigured in ways that first and foremost ensure the continued provision of their core societal functio

The present article departs from the increased significance ascribed to questions concerning arts and aesthetics in contemporary academic theology as well as in church life. This development is given the designation ‘aesthetical turn’ and the content of the article tries to, in a broad outline, situate this phenomenon in the history of philosophical reflection on aesthetic issues. Originally an En

Waardenburg-Shah syndrome (Waardenburg syndrome type IV-WS4) is an auditory-pigmentary disorder that combines clinical features of pigmentary abnormalities of the skin, hair and irides, sensorineural hearing loss, and Hirschsprung disease (HSCR). Mutations in the endothelin-B receptor (EDNRB) gene on 13q22 have been found to cause this syndrome. Mutations in both alleles cause the full phenotype,

Social insects such as termites live in colonies in which cooperation is assumed by all individuals developing into castes to which specific tasks are allocated. Little has been reported about molecular aspects underlying termite caste-specific gene expression. Genetic regulation has recently been hypothesized to govern caste-specific traits and physiology in social insects. Cytochrome c oxidase (