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Residue-specific pK(a) determination of lysine and arginine side chains by indirect N-15 and C-13 NMR spectroscopy: Application to apo calmodulin

Electrostatic interactions in proteins can be probed experimentally through determination of residue-specific acidity constants, We describe here triple-resonance NMR techniques for direct determination of lysine and arginine side-chain protonation states in proteins. The experiments are based on detection of nonexchangeable protons over the full range of pH and temperature and therefore are well

N-Doping Donor-Dilute Semitransparent Organic Solar Cells to Weaken Donor : Acceptor Miscibility and Consolidate Donor-Phase Continuity

Lightweight and semi-transparent organic solar cells (ST-OSCs) offer bright promise for applications such as building integrated photovoltaics. Diluting donor content in bulk-heterojunction active layers to allow greater visible light transmittance (AVT) effectively enhances device transparency, yet the ineluctable compromise of the donor-phase continuity is challenging for efficient charge transp

Complex product form generation in industrial design: A bookshelf based on Voronoi diagrams

Complex product form generation methods have rarely been used within the field of industrial design. The difficulty in their use is mainly linked to constraints – such as functionality, production and cost – that apply to most products. By cou-pling a mathematically described morphology to an optimisation system, it may be possible to generate a complex product form, compliant with engineering and

Climate Change, Adaptation, and Formal Education: the Role of Schooling for Increasing Societies' Adaptive Capacities in El Salvador and Brazil

With a worldwide increase in disasters, the effects of climate change are already being felt, and it is the urban poor in developing countries who are most at risk. There is an urgent need to better understand the factors that determine people's capacity to cope with and adapt to adverse climate conditions. This paper examines the influence of formal education in determining the adaptive capacity

Gotländsk Utveckling AB - en kvalitativ studie i Landsbygds- och Gotlandsupprorets deltagares attityder till regionalpolitiken på Gotland

Rural development on the island of Gotland has been in decline for years. In the year 2011/12, two uprisings were triggered. The first, the “Countryside Uprisings” was started against the local authority’s move to shut down 11 schools in the countryside and the second, the “Gotlandic Uprising” was against the high cost of ferry travel between Got-land and the Swedish mainland. The undercurrent of

How the Concept of the Ideal Victim of Trafficking Contributes to Re-victimize Vulnerable Populations-Human Trafficking in the People’s Republic of China Analyzed Through the Lenses of Feminist Victimology

The aim of this thesis is to demonstrate how the concept of the ideal victim of crime contributes to re-victimize significant populations exploited by human traffickers. The argument is that seeing women trafficked in the sex industry as the norm together with a focus only on “women and children” as victims/survivors contribute to further hide-and therefore re-victimize-men and young boys. The Peo

Att leva med lungcancer

Lungcancer är världens vanligaste cancerform och i Sverige den näst vanligaste cancerformen bland män och den fjärde vanligaste hos kvinnor. Patienter med lungcancer har dålig prognos och multipla symtom under loppet av sjukdomen, vilket ställer stora krav på sjuksköterskans interventioner. Syftet med denna litteraturstudie var att studera fysiologiska och psykosociala aspekter hos patienter som l

Översättning och validering av intensive care unitmemory tool

Patienter efter intensivvårdsvistelse minns fragmentariskt och på ett annorlunda sätt jämfört med andra patienter. Ett instrument på svenska för att standardiserat mäta och värdera vad patienter har för minnen efter intensivvårdsvistelsen har saknats och bromsat forskningen. ”Intensive Care Unit Memory Tool” (ICU Memory Tool) som utvecklats av Christina Jones, är ett standardiserat instrument för

Kost- och motionsvanor hos ungdomar

Det allmänna syftet med studien var att kartlägga och beskriva kost och motionsvanor hos elever i årskurs nio i Malmö. Det specifika syftet var att belysa om eventuella samband mellan kost och motion och social bakgrund förekom.Totalt ingick fem klasser i studien, tre klasser från höginkomst områden och två klasser från låginkomst områden. Alla klasser kom från olika skolor.Som underlag för val av

From Undertaker to Funeral Director: A Social Change in Cyprus

How often do we think of our own death? And how often do we stop and think of the changes surrounding death that affect our lives? Thanatology, the study of death and dying, examines death from different perspectives. Following a thanatological path, this research aimed to explore the relationship between death and technology in terms of social change, specifically in the Republic of Cyprus. F

Chlorophyll biosynthesis in higher plants. Regulatory aspects of 5-aminolevulinate formation

Chlorophyll, heme, phytochrome and siroheme biosynthesis in higher plants is regulated by the supply of their precursor 5-aminolevulinate (ALA), which is derived from glutamate. Glutamate conversion to ALA occurs only in the plastid and requires chloroplast coded tRNA(Glu) and nuclear coded glutamyl-tRNA synthetase, glutamyl-tRNA reductase and glutamate 1-semialdehyde aminotransferase. The chromos

The incidence of trisomy 8 as a sole chromosomal aberration in myeloid malignancies varies in relation to gender, age, prior iatrogenic genotoxic exposure, and morphology

Although trisomy 8 as a sole change is one of the most common chromosomal abnormalities in myeloid malignancies, it is largely unknown if the incidence of this aberration is influenced by other factors of clinical importance. In the present study, the frequencies of isolated +8 in relation to gender, age, previous treatment with chemo- or radiotherapy, and morphologic subtype were ascertained in p

Urban driving patterns - characterisation, variability and environmental implications.

Popular Abstract in Swedish Fordons körmönster, dvs deras hastighets- och accelerationsprofiler, påverkar avgasutsläpp och bränsleförbrukning avsevärt. Detta projekt syftade till att undersöka körmönster i tätort genom att behandla följande delområden: 1) Hur kan körmönster mätas?, 2) Hur kan körmönster beskrivas? – dvs att finna mått för att karakterisera olika egenskaper hos körmönster., 3) Vad Driving patterns, i.e. the speed and acceleration profiles of vehicles affect exhaust emission and fuel consumption considerably. This project was aimed at investigating urban driving patterns by focusing on the following issues: 1) how to measure driving patterns, 2) measures for the description of driving patterns, 3) identification of characteristics of driving patterns that have significant ef

Cloning and sequencing of the Bet v 1-homologous allergen Fra a 1 in strawberry (Fragaria ananassa) shows the presence of an intron and little variability in amino acid sequence

The Fra a I allergen in strawberry (Fragaria ananassa) is homologous to the major birch pollen allergen Bet v 1, which has numerous isoforms differing in terms of amino acid sequence and immunological impact. To map the extent of sequence differences in the Fra a I allergen, PCR cloning and sequencing was applied. Several genomic sequences of Fra a 1, with a length of either 584, 591 or 594 nucleo

Konkurrensskadeavgiften - ett effektivt redskap i preventivt syfte?

Konkurrensskadeavgiften introducerades i lagstiftningen i syfte att avskräcka företag från att på ett otillåtet sätt begränsa konkurrensen. Avgiften är avsedd att tillämpas då företag missbrukat sin dominerande ställning eller då flera företag väljer att delta i ett konkurrensbegränsande samarbete. Det har dock framförts kritik huruvida konkurrensskadeavgiften fått den avskräckande effekt som lags