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Initial person reference in providence island sign language

When referring to non-present entities, speakers and signers can select from a range of different strategies to create expressions that range from extremely concise to highly elaborate. This design of referring expressions is based partly on the availability of contextual information that can aid addressee understanding. In the small signing community of Providence Island, signers' heavy reliance

Athlete mental health in the Olympic/Paralympic quadrennium : a multi-societal consensus statement

This consensus statement is the product of the Second International Think Tank on Athlete Mental Health, held on the initiative of the International Society of Sport Psychology. The purposes of the Think Tank were to engage international sport psychology societies and organisations in a discussion about athlete mental health as embedded in an Olympic/Paralympic cycle, and to develop practical reco

Political Economy in Geographic Research: Institutionalist versus Marxist Approaches

Since the rise of radical geography in the early 1970s, political economy has been crucial in examining the spatial dynamics of capital in economic geography. Marxist and non-Marxist (particularly institutionalist) economic geographers use political economy to challenge non-political economy approaches that ignore the relationship between microeconomic processes and their spatial manifestations an

Development of the NNBAR Experiment at the ESS : Design of the Second Neutron Source and Towards the Realisation of Time Projection Chamber

This thesis contributes to the development of the proposed NNBAR experiment at theEuropean Spallation Source (ESS), which aims to search for free neutron-antineutron oscillations with unprecedented experimental sensitivity. Achieving this goal requires both an intense beam of cold neutrons and a detector capable of reconstructing the pionic final state expected from antineutron annihilation on a c

Exhibition in Lund, Sweden: Following the fish : films, drawings and full-scale prototypes developed through a workshop-based artistic research project

Following the Fish—an artistic research project exploring architecture, migration and collective practice through workshop-based methodologies—was presented in 2024 as part of the exhibition UnFold: Exploring Artistic Directions in Architectural Research at Lund University.The project was developed through a series of workshops across Barcelona, Lund and Venice, engaging with the spatial and socia

Reduced Expression Level of Protein Phosphatase PPM1E Serves to Maintain Insulin Secretion in Type 2 Diabetes

Reversible phosphorylation is an important regulatory mechanism. Regulation of protein phosphorylation in β-cells has been extensively investigated, but less is known about protein dephosphorylation. To understand the role of protein dephosphorylation in β-cells and type 2 diabetes (T2D), we first examined mRNA expression of the type 2C family (PP2C) of protein phosphatases in islets from T2D dono

Instituting: Public Program

Instituting (Athens, 2021)What could processes of self-organizing and collective making look like in the current landscape? In what ways might they affect public processes of social improvisation? How might such forms of “instituting” give rise to other forms of institutions? Inviting theoretical as well as practical approaches, this edition of the New Alphabet School studies “instituting” as an i

Bcl-2 but not FOXP1, is an adverse risk factor in immunochemotherapy-treated non-germinal center diffuse large B-cell lymphomas

Non-germinal center (non-GC) phenotype, high level expression of the transcription factor forkhead box protein P1 (FOXP1) and anti-apoptotic protein Bcl-2 have been identified as unfavorable prognostic factors for diffuse large B-cell lymphoma (DLBCL) patients treated with chemotherapy. Our aim was to re-evaluate the prognostic impact of these biologic factors on the survival of the patients treat

Genomic investigation of alpha-synuclein multiplication and parkinsonism

Objective: Copy number variation is a common polymorphic phenomenon within the human genome. Although the majority of these events are non-deleterious they can also be highly pathogenic. Herein we characterize five families with parkinsonism that have been identified to harbor multiplication of the chromosomal 4q21 locus containing the a-synuclein gene (SNCA). Methods: A methodological approach us

Alpha-1-microglobulin: Innate defence against pathological oxidation

Oxidative stress has been implicated as an important factor in the progression of many diseases. An imbalance in the redox-system may cause oxidation of cells and molecules, which might subsequently lead to tissue damage. The research presented in this thesis has focused on elucidating a possible involvement of the human protein alpha-1-microglobulin in the defence against pathological oxidation.

Vascular Endothelin and Angiotensin Receptors Regulation in Inflammatory Arterial Disorders

The present thesis is aimed to examine the hypothesis that the degree of vascular inflammation correlates with the expression of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). In addition, patients with giant cell arteritis (GCA) were also investigated because o

Alternate States of Proteins Revealed by Detailed Energy Landscape Mapping

What conformations do protein molecules populate in solution? Crystallography provides a high-resolution description of protein structure in the crystal environment, while NMR describes structure in solution but using less data. NMR structures display more variability, but is this because crystal contacts are absent or because of fewer data constraints? Here we report unexpected insight into this

Plastic response to pond drying in tadpoles Rana temporaria: tests of cost models

Tadpoles from two types of ponds, temporary and permanent, were raised in a common garden experiment. There was no clear effect of pond type on development rate (time for metamorphosis). From each sibship, one group was raised under a constant water regime (deep tanks) and one was subject to simulated pond drying (shallow tanks). The tadpoles exhibited a plastic response to pond drying: they metam

Improve Sofa Assembly through Automation and Redesign of the Processes Case: Current Design

Objective: To redesign the current assembly process of the Ektorp Sofa from IKEA in order to improve cycle times, quality levels and to reduce, if possible, costs associated with manufacturing, production times and materials. IKEA wants to increase either the productivity or the quality standard of the Ektorp Sofa by simplifying the processes involved in the construc-tion of the sofa and modernizi

Synthesis development towards new pyranoside-based β4GalT7 inhibitors

Proteoglycans (PG) are comprised of a core protein with a varying number of glycosaminoglycan (GAG) chains attached. Both PGs and GAG chains are involved in biological processes such as cell growth and dif-ferentiation. Both their structure and the expression of enzymes involved in their biosynthesis differ between cancer cells and healthy cells. Heparan sulfate(HS) and chondroitin sulfate/dermata

Franchising ur ett konkurrensperspektiv - Är regleringen för franchising tillräcklig eller finns det risk för snedvridning av konkurrensen på den inre marknaden?

Franchising är egentligen ett företagsekonomiskt begrepp vars avtal berör många rättsområden såsom konkurrensrätt, avtalsrätt, immaterialrätt samt arbetsrätt. Det en verksamhetsform som kombinerar ett lyckat beprövat affärskoncept med egenföretagande. Det är en specialform av ett återförsäljaravtal, men bör enligt EU-domstolens avgörande i mål C-161/84 Pronuptia de Paris, inte räknas som en distriFranchising is an economic concept in business law, which relates to several legal areas of law such as competition law, contract law, intellectual property law and labor law. It is a business strategy, which combines a successful proven business concept with selfemployment. Franchising is a special form of a reseller agreement, but should, according to the judgment from the EU Court of Justice in

The Department of English in Lund : Working Papers in Linguistics Vol. 3

The Department of English in Lund: Working Papers in Linguistics is an annual volume produced by the English Department at Lund University in Sweden. Its main aim is to publicize research being carried out by staff and post-graduate students in the department, but we are also pleased to include contributions from members of neighbouring departments and universities. The contributions in volume 3

Floating-Point Analog-to-Digital Converter

Popular Abstract in Swedish I denna avhandling har jag undersökt hur man kan utöka det dynamiska omfånget utan att öka noggrannheten i en analog-till-digital omvandlare med en flyttalsliknande lösning. Den valda lösningen går ut på att man förstärker en analog insignal med flera oberoende analoga förstärkare med skilda förstärkningar. Sedan väljs den förstärkare som ger den starkaste utsignalen s

Causes and predictors of death in cerebral venous thrombosis

Background and Purpose - The causes of death of patients with cerebral venous thrombosis (CVT) have not been systematically addressed in previous studies. We aimed to analyze the causes and predictors of death during the acute phase of CVT in the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) to identify preventable or treatable causes. Methods - ISCVT is a multinational,