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International Endometrial Tumor Analysis (IETA) terminology in women with postmenopausal bleeding and sonographic endometrial thickness ≥ 4.5 mm : agreement and reliability study

Objective: To estimate intra- and interrater agreement and reliability with regard to describing ultrasound images of the endometrium using the International Endometrial Tumor Analysis (IETA) terminology. Methods: Four expert and four non-expert raters assessed videoclips of transvaginal ultrasound examinations of the endometrium obtained from 99 women with postmenopausal bleeding and sonographic

Urban and agricultural soils : Conflicts and trade-offs in the optimization of ecosystem services

On-going human population growth and changing patterns of resource consumption are increasing global demand for ecosystem services, many of which are provided by soils. Some of these ecosystem services are linearly related to the surface area of pervious soil, whereas others show non-linear relationships, making ecosystem service optimization a complex task. As limited land availability creates co

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model

Expanded CAG repeats lead to debilitating neurodegenerative disorders characterized by aggregation of proteins with expanded polyglutamine (polyQ) tracts. The mechanism of aggregation involves primary and secondary nucleation steps. We show how a noncanonical member of the DNAJ-chaperone family, DNAJB6, inhibits the conversion of soluble polyQ peptides into amyloid fibrils, in particular by suppre

Estimating the harms and benefits of prostate cancer screening as used in common practice versus recommended good practice : A microsimulation screening analysis

BACKGROUND: Prostate-specific antigen (PSA) screening and concomitant treatment can be implemented in several ways. The authors investigated how the net benefit of PSA screening varies between common practice versus “good practice.”. METHODS: Microsimulation screening analysis (MISCAN) was used to evaluate the effect on quality-adjusted life-years (QALYs) if 4 recommendations were followed: limite

I ett andetag : En kulturanalys av astma som begränsning och möjlighet

Though asthma is a commonly occurring disorder today, the development and introduction of anti-inflammatory drugs in treating it has changed the possibilities of living with it. At the same time, the Swedish guidelines for asthma care have changed: the patient is to take responsibility for her or his chronic illness to attain full quality of life. The study aims to make a cultural analytical inves

Luvre-069svenssonbacksvala

Test "Title" ORNIS SCANDINAVICA 17: 221-229. Copenhagen 1986 Number of pairs, timing of egg-laying and clutch size in a subalpine Sand Martin Riparia riparia colony, 1968-1985 Soren Svensson Svensson, S. 1986. Number of pairs, timing of egg-laying and clutch size in a subal- pine Sand Martin Riparia riparia colony, 1968-1985. - Ornis Scand. 17: 221-229. A Sand Martin colony in the subalpine (subar

https://www.luvre.lu.se/sites/luvre.lu.se/files/luvre-069svenssonbacksvala.pdf - 2026-06-18

GAVIN : Gene-Aware Variant INterpretation for medical sequencing

We present Gene-Aware Variant INterpretation (GAVIN), a new method that accurately classifies variants for clinical diagnostic purposes. Classifications are based on gene-specific calibrations of allele frequencies from the ExAC database, likely variant impact using SnpEff, and estimated deleteriousness based on CADD scores for >3000 genes. In a benchmark on 18 clinical gene sets, we achieve a sen

β-decay study of Cu77

A β-decay study of Cu77 has been performed at the ISOLDE mass separator with the aim to deduce its β-decay properties and to obtain spectroscopic information on Zn77. Neutron-rich copper isotopes were produced by means of proton- or neutron-induced fission reactions on U238. After the production, Cu77 was selectively laser ionized, mass separated, and sent to different detection systems where β-γ

The VMC survey - XLVIII. Classical cepheids unveil the 3D geometry of the LMC

We employed the VISTA near-infrared YJKssurvey of the Magellanic System (VMC) to analyse the Y, J, and Ks light curves of δCepheid stars (DCEPs) in the Large Magellanic Cloud (LMC). Our sample consists of 4408 objects accounting for 97 per cent of the combined list of OGLE IV and Gaia DR2 DCEPs. We determined a variety of period-luminosity (PL) and period-Wesenheit PW relationships for Fundamental

Fluid Management, Intra-Abdominal Hypertension and the Abdominal Compartment Syndrome : A Narrative Review

Background: General pathophysiological mechanisms regarding associations between fluid administration and intra-abdominal hypertension (IAH) are evident, but specific effects of type, amount, and timing of fluids are less clear. Objectives: This review aims to summarize current knowledge on associations between fluid administration and intra-abdominal pressure (IAP) and fluid management in patient

Impact of Post Manufacturing Handling of Protein-Based Biologic Drugs on Product Quality and User Centricity

This article evaluates the current gaps around the impact of post-manufacturing processes on the product qualities of protein-based biologics, with a focus on user centricity. It includes the evaluation of the regulatory guidance available, describes a collection of scientific literature and case studies to showcase the impact of post-manufacturing stresses on product and dosing solution quality.

The 1+Million Genomes Minimal Dataset for Cancer

Defining minimal standards for data collection is key to creating interoperative, searchable genomic and clinical databases. We highlight here the 1+Million Genomes Minimal Dataset for Cancer, encompassing 140 items in 8 domains to foster the collection of cancer data, inform transnational cooperation and advance precision cancer medicine.

Comprehensive Assessment of BARD1 Messenger Ribonucleic Acid Splicing With Implications for Variant Classification

Introduction: Case–control analyses have shown BARD1 variants to be associated with up to >2-fold increase in risk of breast cancer, and potentially greater risk of triple negative breast cancer. BARD1 is included in several gene sequencing panels currently marketed for the prediction of risk of cancer, however there are no gene-specific guidelines for the classification of BARD1 variants. We pres

Alla familjers bibliotek? En fallstudie kring hur folkbiblioteken i Malmö stad görs tillgängliga för spädbarn med flerspråkiga familjer

The aim of this master thesis is to investigate how the public libraries in the city of Malmö in Sweden, work with and towards babies under the age of one and their parents, with a specific focus on multilingual families. We also aim to investigate the awareness amongst the librarians in their meeting with this group. For this we use critical theory and an intersectional perspective using mainly t

Characterizing visual read tau-PET-negative participants with Alzheimer's disease dementia

INTRODUCTION: A subset of amyloid beta (Aβ)-positive Alzheimer's disease (AD) patients is tau-positron emission tomography (PET) negative. We aimed to characterize this subgroup using [18F]flortaucipir PET visual read (VR), as this is important for prognosis and selection for therapies. METHODS: Aβ-positive VR tau-PET-negative AD dementia patients (AD A+T−) were compared to tau-PET-positive AD pat

The human dimension of biodiversity changes on islands

Islands are among the last regions on Earth settled and transformed by human activities, and they provide replicated model systems for analysis of how people affect ecological functions. By analyzing 27 representative fossil pollen sequences encompassing the past 5000 years from islands globally, we quantified the rates of vegetation compositional change before and after human arrival. After human

10212016 679 49 mp31 johnson jpp 2015 1

OP-JPEP150093 373..383 Predicting Later Study Withdrawal in Participants Active in a Longitudinal Birth Cohort Study for 1 Year: The TEDDY Study Suzanne Bennett Johnson,1 PHD, Kristian F. Lynch,2 PHD, Judith Baxter,3 MA, Barbro Lernmark,4 PHD, Roswith Roth,5 PHD, Tuula Simell,6 PHD, Laura Smith,2 PHD, and The TEDDY Study Group7 1Department of Behavioral Science and Social Medicine, Florida State U

https://www.teddy.lu.se/sites/teddy.lu.se/files/10212016_679_49_mp31_johnson_jpp_2015_1.pdf - 2026-06-18

About the Centre for Aesthetics and Business Creativity

Our PartnersOur TeamAffiliated StaffAdvisory boardOur SupportersThe Centre for Aesthetics and Business Creativity (ABC) is a centre that loves its periphery-pulling forces. It wants to extend the research-basis for understanding and practicing organizational creativity in pursuit of values that enhance our quality of life, as citizens and consumers.ABC aims to push the boundaries by engaging acros

https://www.lusem.lu.se/organisation/research-centres/centre-aesthetics-and-business-creativity-abc/about-centre-aesthetics-and-business-creativity - 2026-06-15