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Hemicelluloses from Agricultural and Forestry Crops Isolation, Characterisation, and Enzymatic Hydrolysis

Popular Abstract in Swedish Hemicellulosa är en fantastisk källa av förnyelsebar råvara, vars användning har potental att bli kraftigt utökad i framtiden. Hemicellulosor är tillsammans, med lignin och cellulosa bland de mest förekommande klasserna av ämnen i växtcellernas väggar. Dessa tre beståndsdelar är tätt sammanlänkade, vilket gör det svårt att separera dem från varandra. Hemicellulosor är kHemicelluloses are tremendous sources of renewable raw materials, which utilisation have the potential to be highly increased in the future. Hemicelluloses are among the major groups of compounds in plant cell walls, together with cellulose and lignin. These three components are closely associated, making them difficult to separate from each other. Hemicelluloses are complex polysaccharides and tw

Profiling the cancer proteome

Popular Abstract in Swedish Cancer är en komplex och heterogen sjukdom där celler har börjat växa okontrollerat och denna sjukdom är idag ett stort hälsoproblem. På grund av diffusa symptom upptäcks cancern ofta i ett sent stadium. Otillräcklig kunskap om olika fenotyper hindrar utvecklingen av riktad behandling och patienter svarar därför väldigt olika på en given behandling. Denna avhandling ärCancer is a complex and heterogeneous disease where cells have started to grow uncontrolled and this disease remains a major health problem. Because of diffuse symptoms it often presents at a late stage. Insufficient understanding of the different phenotypes hinders the development of targeted therapeutics and consequently patients show a diverse range of responses to a given treatment. This thes

Transcriptional Regulation of HIF2A/EPAS1 in Neuroblastoma

Popular Abstract in Swedish Cancer är den vanligaste dödsorsaken bland barn mellan 1–14 år i Sverige. Neuroblastom, som nästan uteslutande drabbar barn, är en aggressiv cancersjukdom som har sitt ursprung i det sympatiska (icke-viljestyrda) nervsystemet. I frisk vävnad råder strikt balans mellan celldelning och celldöd, medan cancerceller kännetecknas av en ohämmad celldelning och minskad celldödNeuroblastoma is a childhood tumor of the developing sympathetic nervous system (SNS) and is the most commonly diagnosed form of cancer in children before one year of age. Although survival curves have improved for these patients during the past decades, the conventional regimen of neuroblastoma treatment has clearly reached a plateau of efficiency with regard to increasing the survival rates of h

Brottsprovokation och straffansvar - En studie av betänkandet till Lag (2027:000) om särskilda provokativa åtgärder

Provokation saknar idag uttrycklig lagreglering i svensk rätt och har under lång tid varit föremål för rättslig diskussion. Med provokation, agent provo-ceateur, avses utredningsåtgärder genom vilka myndigheter aktivt förmår eller påverkar en person att handla på ett visst sätt, vilket kan leda till att brottslig verksamhet avslöjas men samtidigt innebär en risk för att brott framkallas. UtvecklinCriminal provocation currently lacks explicit statutory regulation in Swedish law and has long been the subject of legal debate. Provocation, agent provo-ceatur, may be described as investigative measures through which authorities actively influence an individual to engage in conduct that may reveal criminal activity, while also risking the creation of new. The increase in organised crime, as well

Clinical Outcomes in Percutaneous Coronary Intervention: Studies on Chronic Coronary Syndrome and Drug-Coated Balloons

Background: Percutaneous coronary intervention (PCI) is frequently used in the treatment of chronic coronary syndrome (CCS), although its impact on long-term prognosis and symptom relief remains debated. Among patients undergoing revascularisation with PCI, data on clinical outcomes following drug-coated balloon (DCB) based PCI in unselected patient populations is limited, and the comparative effe

An indispensable means in a free state : The Swedish Freedom of the Press Act of 1766

The eighteenth century marks a watershed in European intellectual history. It witnessed the development of many civil rights ideas that were prerequisites for the emergence of modern political systems. One principle that appears to be supported by numerous empirical examples is that evolving political pluralism fostered the right to express one’s views with a certain degree of freedom. This articl

WHY THE KIMBERLY PROCESS DOES NOT WORK AND WHAT THE COMING FIGHT OVER MAN-MADE DIAMONDS MEANS FOR THE FUTURE OF BLOOD DIAMONDS

This thesis analyzes blood diamonds and the human rights issues surrounding them. The problems they pose and the promises and limitations of the Kimberly Process are covered along with the development and future impact of man-made diamonds on the demand side of the blood diamond problem. There are two main sections--the first covers blood diamonds and the second man-made diamonds. The introduction

Civil Society in Russia, Myth and Reality

Russia is a country in transition towards democracy. After a long period of economical and political suppression, people have a chance to participate in society's life, to affect the ruling government and to express their views more freely. However, in order for the democratic transition to continue, it is not enough to merely have a chance to participate and be active&semic there should b

Koncernbidrag vid omstrukturering - Skatteflykt eller ej?

Koncernbidraget är ett verktyg som ofta används av bolag för att kunna erhålla kontanter till bl.a. investeringar tack vare de skattelättnader som bidraget skapar. Systemet med koncernbidrag är uppbyggt genom en strukturbildning av bolagsformen koncern som förgrenas ut i form av olika dotterbolag. Nyligen kom ett avgörande från Högsta förvaltningsdomstolen om just koncernbidrag och under vilka forThe Group contribution is a tool, often used by companies to achieve more money in order to invest and ease up the tax burden. The system is to build a concern with subsidiary companies and then make transfers to each subsidiary.This is not a problem in most cases, but would it be achievable to use this method in all tax related situations? When restructuring has been executed in a concern, it’s n

Fatty Acid Amide Hydrolase-Dependent Generation of Antinociceptive Drug Metabolites Acting on TRPV1 in the Brain

The discovery that paracetamol is metabolized to the potent TRPV1 activator N-(4-hydroxyphenyl)-5Z, 8Z, 11Z, 14Z-eicosatetraenamide (AM404) and that this metabolite contributes to paracetamol's antinociceptive effect in rodents via activation of TRPV1 in the central nervous system (CNS) has provided a potential strategy for developing novel analgesics. Here we validated this strategy by examining

Ideals and Maximal Commutative Subrings of Graded Rings

This thesis is mainly concerned with the intersection between ideals and (maximal commutative) subrings of graded rings. The motivation for this investigation originates in the theory of C*-crossed product algebras associated to topological dynamical systems, where connections between intersection properties of ideals and maximal commutativity of certain subalgebras are well-known. In the last few

Cytogenetic polyclonality in hematologic malignancies

The present study was undertaken to ascertain the frequency of cytogenetic polyclonality in various hematologic malignancies and to investigate whether morphologic subgroup, age, gender, or previous genotoxic exposure influences the incidence. Among 2,243 cytogenetically investigated hematologic malignancies, 10 acute myeloid leukemias (AML), 5 myelodysplastic syndromes (MDS), 2 acute lymphoblasti

The methylmercury cycle in Little Rock Lake during experimental acidification and recovery

The cycle of waterborne methylmercury (meHg) in Little Rock Lake is characterized by a period of accumulation during summertime (when the lake is warm and open to the atmosphere) and a period of decline during winter (when the lake is scaled by ice). We followed this cycle for 16 yr. during which time the lake was acidified with H,SO., and then allowed to recover naturally as part of a long-term f

Växandets gestaltning i Peter Pohls romansvit om Micke

Peter Pohl was born in Germany in 1940 but grew up in Stockholm, a setting reflected in many of his books. Pohl, a researcher at the Royal Technical University in Stockholm, made his fiction debut with the multi-prize-winning novel "Janne, min vän" (1985), and is internationally acclaimed for, among other things, the way in which his teenage novels highlight existential questions. The purpose of t

Genomewide Association Study Using a High-Density Single Nucleotide Polymorphism Array and Case-Control Design Identifies a Novel Essential Hypertension Susceptibility Locus in the Promoter Region of Endothelial NO Synthase.

Essential hypertension is a multifactorial disorder and is the main risk factor for renal and cardiovascular complications. The research on the genetics of hypertension has been frustrated by the small predictive value of the discovered genetic variants. The HYPERGENES Project investigated associations between genetic variants and essential hypertension pursuing a 2-stage study by recruiting cases

Kinin-Stimulated B1 Receptor Signaling Depends on Receptor Endocytosis Whereas B2 Receptor Signaling Does Not.

Kinins are potent pro-inflammatory peptides that act through two G protein-coupled receptor subtypes, B1 (B1R) and B2 (B2R). Kinin-stimulated B2R signaling is often transient, whereas B1R signaling is sustained. This was confirmed by monitoring agonist-stimulated intracellular Ca(2+) mobilization in A10 smooth muscle cells expressing human wild-type B2R and B1R. We further studied the role of rece