Filtyp
Inhibition of mitochondrial permeability transition (mPT) has emerged as a promising approach for neuroprotection and development of well-tolerated mPT inhibitors with favorable blood-brain barrier penetration is highly warranted. In a recent study, 28 clinically available drugs with a common heterocyclic structure were identified as mPT inhibitors e.g. trifluoperazine, promethazine and nortriptyl
The Symphony study showed that at 1 year posttransplant, a regimen based on daclizumab induction, 2 g mycophenolate mofetil (MMF), low-dose tacrolimus and steroids resulted in better renal function and lower acute rejection and graft loss rates compared with three other regimens: two with low-doses of cyclosporine or sirolimus instead of tacrolimus and one with no induction and standard cyclospori
The quantum theory of measurement has been with us since quantum mechanics (QM) was invented. It has recently been invigorated, partly due to the increasing interest in quantum information science. In this, partly pedagogical review, I attempt to give a self-contained overview of the basis of (non-relativistic) QM measurement theory expressed in density matrix formalism. I will not dwell on the ap
This thesis examines the role of beamlines with publication metadata from the European Synchrotron Radiation Facility (ESRF a large scientific facility offering diverse conditions for scientific research. As a user-oriented Big Science facility, the ESRF channels extremely brilliant light into different experimental areas called beamlines that house specific instruments that cater to the needs of
The frame story
takes place in a dystopian Europe, possibly some kind of European Union around 2050 – in a state of conflicts and decay. The protagonists are a retired general, Piscator (cf. Fisher King) and a former journalist, Perle Vaus (cf. Perlesvaus/Perceval/Parsifal). She lost her home because of a new genderrelated law and stays homeless with others, covered by the Saxon bridge.
The main aim of this thesis is to analyze the process of institutionalization and neo-/interdisciplinarization in Women’s/Gender/Feminist Studies (WGFS) in Sweden, and the construction of feminist knowledge within this process. Furthermore, the thesis aims to contribute to the feminist debates on academic feminism as a transformative project. Three questions have guided the research process: 1) Ho
Context: It is an enigma that agile projects can succeed ‘without requirements’ when weak requirements engineering is a known cause for project failures. While agile development projects often manage well without extensive requirements test cases are commonly viewed as requirements and detailed requirements are documented as test cases.Objective: We have investigated this agile practice of using t
The present article analyses the relation between politics and historiography in communist Romania (1948- 1989). Since the beginning of the four-decades-long communist dictatorship, history has been turned into an ancillary discipline of the political discourse. The analysis of this peculiar kind of historiography starts from the processes that have determined its political nature and brought to i
Background: Around 70% of all ICU patients are treated with antibiotics whereas up to 30% are suggested as unnecessary. Measuring antibiotic consumption is a prerequisite to improving its use and the purpose of the present investigation was to explore the use of antibiotics in Swedish ICUs. Material and methods: Daily Defined Doses (DDDs) of antimicrobials delivered to Swedish ICUs, 2016–2018, wer
BACKGROUND AND OBJECTIVES: Under the ISBT, the Working Party (WP) for Red Cell Immunogenetics and Blood Group Terminology is charged with ratifying blood group systems, antigens and alleles. This report presents the outcomes from four WP business meetings, one located in Basel in 2019 and three held as virtual meetings during the COVID-19 pandemic in 2020 and 2021.MATERIALS AND METHODS: As in prev
Humanitarian considerations in the Swedish asylum process. A study of the migration authorities’ balancing act between solidarity and inequality. Medical certi cates are becoming increasingly important as a basis for asylum assessments. Using examples from 24 asylum decisions concerning children and their families, the present article discusses how the Swedish Migration Agency and the Migration Co
Background: Baleen whales are a clade of gigantic and highly specialized marine mammals. Their genomes have been used to investigate their complex evolutionary history and to decipher the molecular mechanisms that allowed them to reach these dimensions. However, many unanswered questions remain, especially about the early radiation of rorquals and how cancer resistance interplays with their huge n
The erection of roadside memorials in Sweden is commonly considered a novel practice, appearing during the last 10-15 years. Nevertheless similar precedent practices can be found in the history of Sweden. Stories about marking the site of an unexpected death with a cross could be said to date back to the eleventh century legend of Saint Sigfrid, telling of the first English missionary to spread C
The drafters of the 1990 Dublin Convention knowingly and willfully disregarded divergences among Member States' protection systems. Like a boomerang, the fallacy of this approach has now reappeared in cases where asylum seekers have challenged transfers under the Convention, tasking judges to tackle a problem which its drafters avoided. The core issue of this article is whether and when such diver
Rubella virus encodes a nonstructural polyprotein with RNA polymerase, methyltransferase, and papain-like cysteine protease activities, along with a putative macrodomain of unknown function. Macrodomains bind ADP-ribose adducts, a post-translational modification that plays a key role in host-virus conflicts. Some macrodomains can also remove the mono-ADP-ribose adduct or degrade poly-ADP-ribose ch
För domstolar finns det grundläggande principer som ska prägla domstolsar-betet under hela processen från start till slut. Dessa principer finns i syfte att bland annat upprätthålla rättssäkerheten på en hög nivå, vilket i sin tur är tänkt att garantera de tvistande parterna en rättvis och lika behandling. Dessa principer efterlevs inte alltid fullt ut. Exempelvis kan en domstol, i syfte att utredIn a judicial process, there are essential and foundational principles intended to shape the proceedings from initiation to conclusion. These principles serve a crucial purpose, including the maintenance of a relatively high level of legal certainty, ultimately aiming to ensure fair and equal treatment for the disputing parties. However, these principles are not always fully adhered to. For instan
Uppsatsen undersöker rätten till självbestämmande för ursprungsfolk och huruvida en sådan rättighet existerar inom internationell sedvanerätt och vad omfattningen av en sådan rättighet innebär. Vidare undersöker uppsatsen vilka åtgärder stater har vidtagit för att implementera rättigheten med fokus på aspekterna gällande autonomi och självstyrelse. Detta görs genom att undersöka olika nationella sThis thesis examines the right to self-determination for indigenous peoples and whether such a right exists within international customary law and what the scope of such a right entail. Furthermore, the essay investigates what measures states have taken to implement such a right with a focus on the autonomous and self-governance aspects. This is done by examining different domestic self-government
Syftet med denna uppsats är att undersöka den pågående förflyttningen av palestinier i Gaza efter den 7 oktober 2023. Specifikt syftar uppsatsen till att avgöra om förflyttningen av palestinier utgör ett brott mot mänskligheten enligt internationell straffrätt. Forskningen bygger huvudsakligen på två frågor: Hur definierar och reglerar internationell straffrätt tvångsförflyttning och deportation uThe purpose of this essay is to examine the ongoing displacement of Palestin-ians in Gaza after October 7th, 2023. In specific, the essay aims to determine whether the displacement of Palestinians constitutes a crime against humanity under the international criminal law. The research is based around two main questions: How does international criminal law define and regulate forcible transfer and d
