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TMA20 (MCT-1), TMA22 (DENR) and TMA64 (eIF2D) are eukaryotic translation factors involved in ribosome recycling and re-initiation. They operate with P-site bound tRNA in post-termination or (re-)initiation translation complexes, thus participating in the removal of 40S ribosomal subunit from mRNA stop codons after termination and controlling translation re-initiation on mRNAs with upstream open re
There is a need of problematizing taken for granted assumptions in the conceptualization of collaborative housing when attempting to link collaborative housing and social integration. What are the difficulties and opportunities that migrants and non-migrants face in accessing collaborative housing projects? Addressing such type of questions will help to capture exclusionary processes affecting old
Background: Emergency surgery for acute type A aortic dissection in patients with previous cardiac surgery is controversial. This study aimed to evaluate the association between previous cardiac surgery and outcomes after surgery for acute type A aortic dissection, to appreciate whether emergency surgery can be offered with acceptable risks. Methods: All patients operated on for acute type A aorti
BackgroundPatients with chronic right ventricular (RV) pacing are at an increased risk of heart failure. Previous studies have indicated that cardiac resynchronization therapy (CRT) is underused in this setting, and that there may be sex-based differences in both CRT use and clinical outcome.ObjectiveTo evaluate sex-based differences in CRT use and clinical outcome for patients with new-onset hear
Nature-based solutions (NBS) is a relatively novel concept and real-world application has only started to proliferate in cities, which motivates addressing early attempts of cross-boundary collaboration for implementing NBS. The aim of this paper is to reflect about the process of transdisciplinary research-practice collaboration on NBS and its associated learnings, potentials and challenges. To d
Questions around school choice have attracted growing attention among educational scholars worldwide, and there is by now a burgeoning body of literature that links school choice to (i) the marketization and commercialization in education, (ii) new modes of governance in education, and (iii) individualized patterns of life-planning among families who see themselves increasingly exposed to global c
The radioactive isotope Sn-107 was studied using Coulomb excitation at the REX-ISOLDE facility at CERN. This is the lightest odd-Sn nucleus examined using this technique. The reduced transition probability of the lowest-lying 3/2(+) state was measured and is compared to shell-model predictions based on several sets of single-neutron energies relative to Sn-100. Similar to the transition probabilit
This thesis is mainly concerned with the intersection between ideals and (maximal commutative) subrings of graded rings. The motivation for this investigation originates in the theory of C*-crossed product algebras associated to topological dynamical systems, where connections between intersection properties of ideals and maximal commutativity of certain subalgebras are well-known. In the last few
Popular Abstract in Swedish Cancer är den vanligaste dödsorsaken bland barn mellan 1–14 år i Sverige. Neuroblastom, som nästan uteslutande drabbar barn, är en aggressiv cancersjukdom som har sitt ursprung i det sympatiska (icke-viljestyrda) nervsystemet. I frisk vävnad råder strikt balans mellan celldelning och celldöd, medan cancerceller kännetecknas av en ohämmad celldelning och minskad celldödNeuroblastoma is a childhood tumor of the developing sympathetic nervous system (SNS) and is the most commonly diagnosed form of cancer in children before one year of age. Although survival curves have improved for these patients during the past decades, the conventional regimen of neuroblastoma treatment has clearly reached a plateau of efficiency with regard to increasing the survival rates of h
The discovery that paracetamol is metabolized to the potent TRPV1 activator N-(4-hydroxyphenyl)-5Z, 8Z, 11Z, 14Z-eicosatetraenamide (AM404) and that this metabolite contributes to paracetamol's antinociceptive effect in rodents via activation of TRPV1 in the central nervous system (CNS) has provided a potential strategy for developing novel analgesics. Here we validated this strategy by examining
There is no answer to the question “Are sustainability challenges solvable within capitalism?” which is not already taking sides in a debate about values, perceptions and motivations. There are several different approaches to sustainability, based on assumed feasibilities and expected agents of change. By disclosing one’s own stand in the debate while being aware and acknowledging other possible a
Alkoholkonsumtionen i Sverige är högre än på mycket länge. Med nya överenskommelser, som öppnade möjligheter för alkoholbranschen att marknadsföra sina produkter, utsätts konsumenter för ökad påtryckning av önskad kommunikation från företagen. Företagens kommunikation riktar sig gärna till den yngre allmänheten som ofta formar sina uppfattningar och attityder genom inlärning och erfarenheter. Upps
A set of B(E2) values for the low-lying excited states in the radioactive isotope Sn-109 were deduced from a Coulomb excitation experiment. The 2.87-MeV/u radioactive beam was produced at the REX-ISOLDE facility at CERN and was incident on a secondary Ni-58 target. The B(E2) values were determined using the known 2(+) -> 0(+) reduced transition probability in Ni-58 as normalization with the semicl
The radioactive isotope In-107 was studied using sub-barrier Coulomb excitation at the REX-ISOLDE facility at CERN. Two gamma rays were observed during the experiment, corresponding to the low-lying 11/2(+) and 3/2(-)states. The reduced transition probability of the 11/2(+) state was determined with the semiclassical Coulomb excitation code GOSIA2. The result is discussed in comparison to large-sc
Genetically modified organisms (GMOs) are controversial, especially for food and feed products, mainly due to potential benefits and potential risks. Advocates claim substantial yield improvements and reduced pesticide usage, while opponents claim contamination of non-GMO crops and damage to health and the environment. The European Union (EU) has since 2003 used a cautious approach, where GMO prod
This thesis analyzes blood diamonds and the human rights issues surrounding them. The problems they pose and the promises and limitations of the Kimberly Process are covered along with the development and future impact of man-made diamonds on the demand side of the blood diamond problem. There are two main sections--the first covers blood diamonds and the second man-made diamonds. The introduction
