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This chapter draws on recent literature to outline the trajectory of China’s national development in the fields of gender equality and sexual and reproductive health and rights (SRHR), as well as its global engagement in these fields. By highlighting how Chinese national and global development agendas speak to and depart from each other, it attempts to identify potential synergies and contradictio

Objective: So-called responder analyses are commonly used in randomized controlled trials (RCT) for osteoarthritis and are typically based on observed change from baseline in self-reported pain. However, it is well known in the methodological literature that such responder analyses are misleading. We aimed to illustrate the size of the problem using simulation. Design: We generated individual pain

Background and Aims: Colon capsule endoscopy (CCE) provides a non-invasive alternative to traditional colonoscopy. This study evaluated the feasibility, safety, diagnostic yield (DY), and patient satisfaction of the OMOM CC100 CCE system, with special focus on fully remote (n = 30) and partially remote (n = 89) administration across four centres to advance decentralised models. Methods: This prosp

Influenza A virus (IAV) is a major respiratory pathogen, causing around 650,000 deaths annually. Asignificant transmission pathway for IAV is via expelled respiratory aerosol. For successfultransmission via the aerosol route, IAV must remain infectious following transport from an infectedhost to a susceptible individual. Many environmental factors may affect IAV infectivity, includingambient relat

We investigate subalgebras of finite codimension in. In earlier work we have introduced a way of describing such subalgebras in terms of their so called (subalgebra) spectrum and a set of conditions for subalgebra membership that can be expressed by evaluating polynomials and their derivatives in points of the spectrum only. In this paper we focus on subalgebras with a single element in their spec

Background: Metformin is one of the most used drugs worldwide. Given the increasing use of proteomics in trials, bioresources, and clinics, it is crucial to understand the influence of metformin on the levels of the circulating proteome. Methods: We analysed a combined longitudinal proteomics dataset from the IMPOCT, RAMP and S3WP-T2D clinical trials in 98 participants before and after metformin e

Context. The Near-InfraRed Planet Searcher (NIRPS) is a high-resolution, high-stability near-infrared (NIR) spectrograph equipped with an adaptive optics (AO) system. Installed on the ESO 3.6-m telescope at La Silla Observatory, Chile, it was developed to enable radial velocity (RV) measurements of low-mass exoplanets around M dwarfs and to characterise exoplanet atmospheres in the NIR. Aims. This

Photonics technologies play a crucial role in driving technological advancements within the agrifood industry, aiming to deliver a sustainable food and agriculture, and offering healthy, nutritious and safe food for all of us. Particularly, optical sensors and imaging systems, together with machine-learning processing and advanced lighting, play a pivotal role in monitoring crop and soil health wi

Background: We aimed to assess the risk of serious infections in patients with inflammatory bowel disease (IBD) exposed to different advanced therapies. Methods: We linked nationwide registers and compared rates of incident serious infections in patients with Crohn’s disease (CD) and ulcerative colitis (UC) exposed to medical therapies versus matched general population comparators during 2007-2023

Background: We aimed to determine corticosteroid (CS) use in paediatric inflammatory bowel disease (PIBD, < 18 years), which remains common despite recommendations for limited use and the emergence of steroid-sparing therapies. Methods: We conducted a study of all children in Sweden diagnosed with CD (n = 2460) or UC (n = 2470) in 2006–2022. Nationwide health registers provided annual individual-l

GOALS: To assess the incidence, type, and severity of infections in patients with IBD before and after starting thiopurine therapy.BACKGROUND: Thiopurines have been used for decades in the treatment of inflammatory bowel disease (IBD), yet real-world data regarding the extent and types of infections associated with their use are scarce.STUDY: We included all thiopurine-naive adults with IBD who in

ObjectivePediatric cancer patients are at increased risk for sleep disturbances; however, there are no clinical practice guidelines for treating sleep disturbances in pediatric oncology, resulting in variable approaches to sleep management across clinicians. The current study surveyed clinicians regarding their approaches to assessing and treating sleep.MethodsA total of 200 pediatric oncology cli