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On the missed opportunity cost, GUD, and estimating environmental quality

The missed opportunity cost (MOC), i.e., all foregone alternatives while foraging in a patch, is an important aspect of the cost-benefit analysis of foraging patch use. When making between-environment comparisons it will often be the most important factor influencing behavior, but it has received less interest than other foraging costs. In this paper, we focus on differences between individuals li

The prognostic information of DNA ploidy and S-phase fraction may vary with histologic grade in endometrial carcinoma

DNA ploidy and S-phase fraction (SPF) were determined by flow cytometry on paraffin-embedded tumor material from 243 patients treated during 1980-1985. Patients with well differentiated and moderately differentiated tumors without solid areas (n = 351) formed a low-risk group (corrected 5-year survival 90%). Twenty-four patients, dead of disease within 5 years, were compared with 52 survivors. The

Intermolecular interactions between the SH3 domain and the proline-rich TH region of Bruton's tyrosine kinase

The SH3 domain of Bruton's tyrosine kinase (Btk) is preceded by the Tec homology (TH) region containing proline-rich sequences. We have studied a protein fragment containing both the Btk SH3 domain and the proline-rich sequences of the TH region (PRR-SH3). Intermolecular NMR cross-relaxation measurements, gel permeation chromatography profiles, titrations with proline-rich peptides, and N-15 NMR r

Genetics of autoimmune diseases: a multistep process.

Abstract in UndeterminedIt has so far been difficult to identify genes behind polygenic autoimmune diseases such as rheumatoid arthritis (RA), multiple sclerosis (MS), and type I diabetes (T1D). With proper animal models, some of the complexity behind these diseases can be reduced. The use of linkage analysis and positional cloning of genes in animal models for RA resulted in the identification of

Utvärdering av cykelfälts effekter på cyklisters säkerhet och cykelns konkurrenskraft mot bil

Popular Abstract in Swedish Cykeln som transportmedel har många fördelar för individ och samhälle. Det är ett mycket energisnålt transportmedel, det förorenar inte, bullrar inte, tar liten plats och ger dem som cyklar välbefinnande och motion. Om fler cyklade istället för att åka bil skulle detta medföra trevligare stadsmiljöer. Ökad cykling hade också kunnat bidra till en ökad folkhälsa. För närThis work presents an evaluation of bicycle lane effects on cyclist safety and the ability of bicycles to compete with car traffic. Thirteen Swedish urban streets were studied before and after bicycle lanes were introduced. Data was collected using video recordings, speed studies, road side questionnaires/interviews with cyclists/car drivers, conflict studies and accident analysis. Results showed

Synthesis of boronate-contaming copolymers of N,N-dimethylacrylamide, their interaction with poly(vinyl alcohol) and rheological behaviour of the gels

Cross-linking of polyvinylalcohol (PVA) by boronate-containing copolymer of N,N-dimethylacrylamide (DMAA, 1) was studied and compared to cross-linking of PVA by borate buffers in weakly alkaline solutions. The copolymer of M-w = 19,000 g mor(-1) containing 9 mol% N-acryloyl-m-aminophenylboronic acid (NAAPBA, 2) was prepared by free radical polymerization of the monomers, exhibiting copolymerizatio

Hypoglycemic brain injury. II. Electron-microscopic findings in rat cerebral cortical neurons during profound insulin-induced hypoglycemia and in the recovery period following glucose administration

Severe hypoglycemia was induced in rats by insulin. The brain was fixed in situ by perfusion after the spontaneous EEG had disappeared for 30 or 60 min or after recovery had been induced for 30 or 180 min by glucose injection. Samples from the cerebral cortex from the area corresponding to the previous metabolic studies were processed for electron microscopy. The light-microscopic finding of two d

First-trimester diagnosis on chorionic villi obtained by direct vision technique

An improved technique for direct vision chorionic biopsy that gives a clear view of the amniotic sac was developed. With this technique, used in 48 women prior to vacuum aspiration and in six cases for diagnosis (karyotyping or enzyme analysis), it was possible to obtain chorionic villi free from contamination by maternal tissue. It was also possible to pick out villi (rich in blood vessels and wi

Engraftment of engineered ES cell-derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium

Cellular cardiomyoplasty is an attractive option for the treatment of severe heart failure. It is, however, still unclear and controversial which is the most promising cell source. Therefore, we investigated and examined the fate and functional impact of bone marrow (BM) cells and embryonic stem cell (ES cell)-derived cardiomyocytes after transplantation into the infarcted mouse heart. This proved