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Rats and mice with unilateral damage to the nigrostriatal dopamine system-induced by neurotoxins, such as 6-hydroxydopamine, overexpression of α-synuclein, or injections of toxic synuclein protofibrils-are widely used as experimental models to mimic the loss of dopamine neurons seen in Parkinson's disease. The amphetamine rotation test is commonly used to monitor the extent of motor impairment ind
Transportplanering är mycket komplext. Forskning och praktik är överens om attfärdmedelsandelen för kollektivtrafik och andra hållbara färdmedel behöver öka.Samtidigt är det inte självklart hur vägen dit ska gå och hur man bäst stödjerbeslutsfattarna så att besluten leder till avsedda mål.Denna rapport handlar om planering och analys av infrastrukturprojektet Spårväg syd iStockholms län. Syftet va
Längs stränderna i Italien, Spanien och vid Öresund har vi alla hittat plastföremål som flyter i havet och ligger på stränderna. I Europa hamnar upp till en halv miljon ton plastavfall i haven varje år. Det motsvarar 66 000 sopbilar som dumpar sitt avfall direkt i havet istället för återvinningscentralen. Efter att frågan vuxit under de senaste åren har EU-länderna nu tagit upp kampen mot detta pr
The role of hybridization in evolution has been debated for more than a century regarding bryophytes (mosses, liverworts, and hornworts) as well as most other organisms. Bryophytes have haplodiplontic life cycles with a dominant haploid generation. Hybridization in bryophytes involves fusion of gametes produced by haploid parental gametophytes of different species. The hybrid is thus the short-livThe role of hybridization in evolution has been debated for more than a century regarding bryophytes (mosses, liverworts, and hornworts) as well as most other organisms. Bryophytes have haplodiplontic life cycles with a dominant haploid generation. Hybridization in bryophytes involves fusion of gametes produced by haploid parental gametophytes of different species. The hybrid is thus the short-liv
Under ASLA-symposiet hölls för första gången ett panelsamtal om forskningsbehov i språkämnena där lärare, språkforskare och gymnasieelever deltog. I detta kapitel situerar vi idén med panelsamtalet i studier av lärares roll i och för den praktiknära skolforskningen. Vi redogör för några modeller för samverkan mellan lärare och forskare och diskuterar identifierade framgångsfaktorer i praktiknära f
Populärvetenskaplig sammanfattning(Summary in Swedish)Hjärnskada som orsakas av olyckor är en vanlig orsak till både handikapp och död bland vuxna. För 30 år sedan var majoriteten av de som drabbades yngre eller väldigt gamla. Ålderssammansättningen av de som drabbas har skiftat under de senaste 20 åren och nu är det ungefär lika vanligt i alla åldrar. Dessutom är den vanligaste olycksorsaken inte
Cerebral intraventricular hemorrhage in preterm infants continues to be a major clinical problem associated with neurodevelopmental abnormalities manifested by cognitive, behavioral, attentional, social and motor deficits. Hypothesis and aims: The central thesis is that the cytotoxicity of extravasated blood and of consequently released cell-free hemoglobin(Hb) is pivotal for the pathophysiolog
What is an intellectual about in this context? It seems that the traits of British provincial intellectuals in the 50s are snobbery, social sophistication and hierarchical mentality. Their productivity consists of correct, but mediocre articles, and once in a while books, especially compilations. These are the pillars of a decrepit modernism, figment of social respectability, but not of originalit
Background: Hip and groin problems are just as common in ice hockey as they are in soccer. The 5-second squeeze test (5SST) is a valid indicator of hip- and groin-related sporting function (self-reported function) in soccer and is suggested to be interpreted according to a “traffic light” approach in guiding the early identification and management of affected players. It is currently unknown how t
Chronic obstructive pulmonary disease (COPD) is a leading cause of death world-wide. Recently, we showed that COPD is associated with gene polymorphisms in SUMF1, a master regulator of sulfatases. Sulfatases are involved in extracellular matrix remodeling and activated by SUMF1, but their role in the lung is poorly described. We aimed to examine how sulfatases are affected in the airways of patien
Existing knowledge suggests that people's willingness to pay (WTP) for climate change mitigation depends not only on personal characteristics but also on the payment vehicle (PV) that is used to elicit WTP. The aim of this research is to investigate policy-relevant differences in WTP between different PVs to support the design of carbon pri
Climate change has been shown to shift the seasonal timing (i.e. phenology) and distribution of species. The phenological effects of climate change on living organisms have often been tested using first occurrence dates, which may be uninformative and biased. More rarely investigated is how different phases of a phenological sequence (e.g. beginning, central tendency and end) or its duration have
The inclusive production of four isolated charged leptons in pp collisions is analysed for the presence of hard double-parton scattering, using 20.2 fb −1 of data recorded in the ATLAS detector at the LHC at centre-of-mass energy s=8 TeV. In the four-lepton invariant-mass range of 80
We attempt to integrate the literatures on authoritarian regime types and democratic forms of government. We propose a theoretical framework of five dimensions of executive appointment and dismissal that can be applied in both more democratic and more authoritarian regimes: the hereditary, military, ruling party, direct election, and confidence dimensions, respectively. Relying on the Varieties of
Background: Uncomplicated urinary tract infection (uUTI) is common and a majority of patients are prescribed antibiotics. There is little knowledge about antibiotic resistance in urine samples from patients with uUTI in primary health care (PHC). The aim was to describe antibiotic treatment, bacterial findings, the prevalence of resistant E.coli and factors associated with antibiotic resistance. T
Background: The survival rate for dialysis patients is poor. Previous studies have shown improved survival with home hemodialysis (HHD), but this could be due to patient selection, since HHD patients tend to be younger and healthier. The aim of the present study is to analyse the long-term effects of HHD on patient survival and on subsequent renal transplantation, compared with institutional hemod
