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Psoriasiform eruptions have been described in patients treated with dupilumab. This case report describes an adolescent with severe atopic dermatitis who developed a widespread psoriasiform dermatitis 8 months after starting dupilumab. His therapy was switched to abrocitinib resulting in near-complete resolution of the psoriatic lesions with good atopic dermatitis control. This case adds to the li
Regional carbon dioxide (CO₂) and methane (CH₄) source contributions were analysed at two European coastal observatories, El Arenosillo (ARN) in southwestern Spain and Capo Granitola (CGR) in southern Italy, using in situ observations and STILT model simulations from 2006 to 2023, enabling source attribution to biogenic, fossil fuel, anthropogenic, and natural contributions. Model-observation agre
This essay intended to analyze and compare assemblages of both anthropomorphic and zoomorphic clay figurines of Pitted Ware Culture settlements in order to gain insight into how these two types of figurines were handled in comparison to each other in these particular, less common contexts. The compared aspects included quantities of the motifs, fragmentation and find context. Through comparison of
This thesis explores the concept of reuse during prehistory in relation to megalithic tombs, using three passage graves in Södervidinge, Skåne, as a case study. Using a landscape theoretical framework and a phenomenological perspective, the study analyses the spatial relationships between the graves, their relationship to the surrounding landscape, and the experience of the place. The results show
Public execution sites have long remained overlooked within Swedish archaeological research. Only a limited number out of the estimated 500-600 sites have been systematically investigated archaeologically. The public execution sites are strongly associated with death and violence, sanctioned by both the Church and the state, positioning them within what can be conceptualised as dark heritage. This
This thesis compares two qualities of flint, one more fine-grained and one more coarse-grained, from the Late Mesolithic Ertebølle site Skateholm I in Scania, Sweden. This in order to investigate what roles the different qualities of flint had in the technological organisation relating to raw material acquisition, choice of technology, and end-product goals. Through a technical analysis of the fli
The following study provides a comparative analysis of Graeco-Bactrian issues in relation to the coinage of earlier and contemporary Hellenistic dynasties, within an iconological and semiotic theoretical framework. This thesis examines the visual strategies employed by Graeco-Bactrian rulers in their attempts to construct royal legitimacy. Through the close examination of 52 extant Hellenistic coi
The aim of this thesis was to determine if and to what extent leprosy and syphilis was present at the graveyard of St:Jörgen in medieval Malmö, as well as trying to understand if it was used as a leprosy hospital. A total of 42 individuals were studied in this thesis. This thesis was based on previous pathological comments regarding changes to the skeleton that could have been interpreted as eithe
Archaeology and archaeological sciences are inherently spatial disciplines. Thus, it is of no surprise that GIS (Geographic Information System) has found its way into archaeological practice, providing an environment for data organisation, analysis and visualisation. Over the past few decades, archaeogeophysics has become an integral part of archaeological practice. The results of these studie
This thesis aims to clarify the risk that a confined aquifer can be contaminated from a spill of chlorinated solvents from a former dry-cleaning facility. This was investigated by conducting a case study at a former dry-cleaning facility in Bjärred that used PCE as a cleaning agent. The facility was active between the 1940s and 1970s, the spill from the process has had severe consequences with an
This paper aims to contribute to the already ongoing scientific discussion about socioeconomic factors and interpersonal trust. More specifically how parents educational level and view of one's self income influences this relationship. This study takes on a Swedish perspective and measures to what extent different variables affect the relationship. The analysis in this paper uses a multiple re
This study explores whether international female master’s students from non-European countries at Lund University achieve social integration, with a particular focus on friendships and sense of belonging. It also examines whether the university provides sufficient social and institutional resources to support integration. The purpose of the study is to understand what conditions Lund University pr
Ovarian cancer (OC) represents one of the most prevalent and lethal malignancies in women, with a need for novel treatments. A large obstacle in the development of OC therapies is the poor translation between preclinical and clinical results, partially attributable to the use of unsuitable models for drug screening. Common models such as cell lines, organoids, spheroids, tumor-on-a-chip, and anima
Cancer immunotherapy targeting the CD40 receptor on antigen presenting cells (APCs) is a promising treatment strategy that promotes priming of tumor-specific T cells and can revert a suppressive tumor microenvironment. CD40 signaling in dendritic cells (DCs) has been shown to promote maturation, enhance expression of MHC, costimulatory molecules and chemokine receptors, and induce IL-12 secretion,
Single-cell RNA sequencing (scRNA-seq) combined with immune receptor analysis is a significant breakthrough in immunology, enabling detect of gene expression and T-cell receptor (TCR) at the single-cell level in the same sample. However, current "gold standard" methods like 10x Genomics 5' V(D)J rely entirely on fresh samples, which severely limits their application in clinical studi
Denna studie ämnar identifiera olika aspekter av hur svenska värnpliktiga internaliseras genom den militära socialiseringsprocessen under den militära grundutbildningen. Särskilt analyseras hur militära normer, disciplin, hierarki samt roll- och identitetsskapande utvecklas och upprätthålls genom militära rutiner och anpassning till kollektivet inom institutionens ramar. Studien utgår från en kv
Small poikilothermic animals like insects rely on environmental sensing for survival. The ability to detect humidity through specialized sensory neurons is particularly critical, allowing them to maintain water balance across diverse environments. While recent studies have identified key receptors associated with humidity sensing, our understanding of the underlying molecular architecture of these
Background: Patients with relapsing–remitting multiple sclerosis (RRMS) experience fatigue and impaired information processing speed (IPS) frequently, even in the absence of clinical or radiological disease activity. Previous studies investigating associations between fatigue, IPS, neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) have reported conflicting results. Objecti
