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Background and Aims The prognosis of adult-onset type 1 diabetes (T1D) and prognostic factors are sparsely investigated. This study assessed mortality, major adverse cardiovascular events (MACE), and prognostic factors in adult-onset T1D, particularly focusing on those diagnosed at age ≥40. Methods Participants were people diagnosed with adult-onset T1D (n = 10 184) or type 2 diabetes (T2D, n = 37
In this study, we use direct numerical simulations to investigate turbulent premixed ammonia flames assisted by non-equilibrium nanosecond plasma discharges and hydrogen addition. The results reveal the coupling effects of turbulence, the hydrogen concentration in the fuel blend, and plasma discharges on the microscopic structure of the flame and chemical pathways. It is found that the flame front
Machine Learning (ML) offers many opportunities, but its reliance on personal data raises privacy concerns. One such example is the Membership Inference Attack (MIA), which aims to determine whether a specific data point was part of a model’s training dataset. In this paper, we investigate this attack on Random Forests (RFs) and propose a method to quantify their vulnerability to MIA. We also demo
By the end of the eighteenth century, Leiden was a very unhealthy city where life was characterised by disease and untimely death – in particular young children – mainly because of high population density and unhygienic conditions. Morbidity and a high mortality rate gave city life a specific dynamic: many children grew up without one or both parents present, while many elderly men and women had t
The implementation of low-carbon futures requires both the assembling of new technologies, and practices, as well as the ‘unmaking’ of extant high-carbon infrastructures. Here, we bring together geographical, STS, anthropological, and sociological thinking on time to re-conceptualise such processes of unmaking. We argue that a focus on temporalities is especially pertinent to the unmaking of mater
Ferroelectric thin films present a powerful platform for next-generation computing and memory applications. However, domain morphology and dynamics in buried ferroelectric stacks have remained underexplored, despite their importance for real device performance. Here, nanoprobe X-ray diffraction (nano-XRD) is used to image ferroelectric domains inside BiFeO3-based capacitors, revealing local disord
INTRODUCTION: In drug facilitated sexual assault (DFSA) the victim is unable to consent to the sexual act due to influence of alcohol, narcotics, or medicine. Increasing the awareness of characteristics associated with DFSA can assist the judicial system in early recognition of cases and guide public health interventions for reducing DFSA. This study aims to assess characteristics of DFSA victims
Differentiating between abusive and accidental skin lesions in children presents significant challenges. Previous studies of skin lesion patterns have mainly focused on bruises in younger children. In this study, we compare the number, location, and distribution of recent (bruises and abrasions) and older (scars) skin lesions between police-reported cases of physical violence and controls of simil
BACKGROUND: Child abuse continues to pose a significant threat to children's health. The repercussions of abuse are profound, impacting the child's physical, social, and emotional well-being, with potential long-term effects that may extend into adulthood. To assist in identifying health concerns in children associated with exposure to physical abuse, a health questionnaire was developed to be use
BACKGROUND: Atrial fibrillation (AF) often complicates ST-segment–elevation myocardial infarction (STEMI), but data on AF recurrence after first-ever AF during STEMI are scarce. We aimed at assessing the risk of AF recurrence after first-ever transient AF during admission for STEMI. METHODS: We performed a single-center, register-based cohort study. Patients with STEMI discharged alive after prima
Claims to 'crisis' reverberate across societal and academic discourses, as people around the world face dire situations and detrimental challenges. Yet, the study of crisis tends to remain siloed and therefore oblivious to the multi-dimensional nature of crisis, which inhibits learning from one type of crisis to the next. Bringing together a broad team of contributors, this book argues for a new i
Consumption of ultra-processed food is associated with increased caloric intake and impaired health. Here, we conducted a nutrition trial (NCT05368194) with controlled, 2 × 2 crossover design and tested whether ultra-processed food impairs reproductive and metabolic fitness, with further aggravation by excess caloric intake. Comparing the response from an unprocessed to ultra-processed diet identi
Since the introduction of X-ray holotomography in projection geometry, this modality has proven to be highly effective for practical applications in the 100 nm spatial resolution range. However, one of the main obstacles to its implementation is the difficulty of producing a small focal spot, which determines the resolution of the projection microscope. To address this challenge, we present a simp
Sports-related concussions (SRCs) typically occur when the brain is hyperthermic. Acute head-and-neck cooling should, therefore, reduce the brain's metabolic demands, with the potential to improve recovery following an SRC. Elite ice hockey players who underwent head-and-neck cooling after sustaining a concussion (SRC) showed reduced return-to-play times, although further investigation is warrante
