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Objective: The therapies available today for multiple sclerosis (MS) reduce but do not fully control disease activity. The objective of this article is to review the definitions of and treatments for suboptimally controlled MS and highlight the challenges faced by clinicians to increase awareness of recognizing and managing patients with suboptimally controlled MS. Methods: Published literature de
Popular Abstract in Swedish Polymerer är samlingsnamnet på långa molekylkedjor. Runt omkring oss i vårt dagliga liv är vi omgärdade av polymerer så som plaster, lim, fibrer och proteiner. Utvecklingen av många högteknologiska produkter är starkt beroende av polymera material. Grundläggande kunskaper om dem och deras egenskaper är därför viktigt. I ett batteri kan många fördelar erhållas då den koThere is a growing need for multifunctional polymeric materials for the development of several important energy conversion technologies. For example, the polymer electrolyte is a key component in lithium polymer batteries. The basic functions of this electrolyte are to efficiently conduct the lithium ions and physically separate the electrodes. Consequently, these electrolytes should ideally posse
Wetland creation at large, regional scales is implemented as a measure to abate the biodiversity loss in agricultural landscapes and the eutrophication of watersheds and coastal areas by non-point source nutrient pollution (mainly nitrogen). The consequences of creating many new wetlands for biodiversity conservation and nutrient retention (ecosystem functioning) in agricultural landscapes are sti
We have investigated calcium-induced secretion in human neutrophils, using a whole-cell patch-clamp technique. Mobilization of subcellular granules to the cell membrane was followed as the change in membrane capacitance (Delta C-m). Both the magnitude and the kinetics of the response differed between low and high concentrations of Ca2+. A sustained secretion following a short lag phase was induced
BACKGROUND. The objectives of this study were to determine the maximum tolerable dose (MTD), toxicity, efficacy, and feasibility of a sequential regimen of fixed-dose topotecan (1.00 mg/m(2) on Days 1-5) and increasing doses of oral etoposide (50 mg, 75 mg, and 100 mg on Days 6-12 or Days 6-19) in patients with recurrent ovarian carcinoma. METHODS. This multicenter, open-label study was planned as
Calculated absorbed dose distributions from tangential irradiation of the breast have been compared with TLD measurements in a anthropomorfic body-shaped phantom which has gone through all phases of the radiation treatment planning cycle, including mapping of electron densities with a CT scanner, simulation of beam set-up and several treatments with an accelerator. The absorbed doses, measured in
Popular Abstract in Swedish Cancer i tjock- och ändtarm drabbar årligen drygt 5000 svenskar. En rad faktorer har satts i samband med tumöruppkomst i tarmen, bl a ärftlighet, inflammatorisk tarmsjukdom, kost och motion, men det är till stor del okänt hur dessa faktorer orsakar cancerutveckling. Genetiska förändringar styr tumörutvecklingen Tumörerna utvecklas oftast från ett godartat förstadium, Colorectal cancer is one of our most common malignancies and the second leading cause of cancer death worldwide. About 1/3 of the tumors are located in the rectum. Treatment advances such as the introduction of the standardized surgical technique total mesorectal excision (TME), pre-operative radiotherapy, and adjuvant chemotherapy have reduced the previously high local recurrence rates and improv
Purpose: To quantify fixation stability in patients with neovascular age-related macular degeneration (nAMD) at baseline, 3 and 6 months after anti-vascular endothelial growth factor (anti-VEGF) treatment and furthermore asses the implications of an unsteady fixation for multifocal electroretinography (mfERG) measurements. Methods: Fifty eyes of 50 nAMD patients receiving intravitreal anti-VEGF tr
BACKGROUND:The importance of supportive social relationships for psychological well-being has been previously recognized, but the direction of associations between both dimensions and how they evolve when adolescents enter adulthood have scarcely been addressed. The present study aims to examine the gender-specific associations between self-reported friendship network quality and psychological wel
Lokalföreningen vid LiU/LiTH Styrelsen Verksamhetsberättelse 2021 för lokalföreningen av Sveriges Ingenjörer vid LiU/LiTH 1. Medlemsutveckling Under verksamhetsperioden har ett antal nya medlemmar rekryterats. Samtidigt har dock ett flertal medlemmar, främst nyblivna doktorer och licentiater, lämnat universite- tet. Den 31 december 2021 hade lokalföreningen ca 600 medlemmar. Störst antal med- lemm
Sveriges Ingenjörer Lokalföreningen vid LiU/LiTH Styrelsen Verksamhetsberättelse 2023 för lokalföreningen av Sveriges Ingenjörer vid LiU/LiTH 1. Medlemsutveckling Under verksamhetsperioden har ett antal nya medlemmar rekryterats. Samtidigt har dock ett flertal medlemmar, främst nyblivna doktorer och licentiater, lämnat universite- tet. Den 31 december 2023 hade lokalföreningen ca 600 medlemmar. St
Sveriges Ingenjörer Lokalföreningen vid LiU/LiTH Styrelsen Verksamhetsberättelse 2025 för lokalföreningen av Sveriges Ingenjörer vid LiU/LiTH 1. Medlemsutveckling Under verksamhetsperioden har ett antal nya medlemmar rekryterats. Samtidigt har dock ett flertal medlemmar, främst nyblivna doktorer och licentiater, lämnat universite- tet. Den 31 december 2025 hade lokalföreningen ca 600 medlemmar. St
The purpose of this short paper is to present a minimalist account of the syntax of the Swedish Wh-Root-infinitives, trying to characterize the syntax of this generally neglected main clause equivalent while comparing its syntax to the syntax of finite root clauses. See (i) and (ii): (i) Swedish Varför sälj-a huset? why sell-inf house.the 'Why sell the house?' (ii) Swedish Varför sälj-er ni huset?
only using electric-dipole forbidden emission lines, in what we label forbidden-line spectroscopy, we identified several energy levels in cadmium-like tungsten, W26+. The spectrum was recorded at the Shanghai permanentmagnet electron beam ion trap in the visible region. The identifications were supported by large-scale multiconfiguration Dirac-Hartree-Fock calculations which involved careful inves
The current debate on different models of global democracy has at times pitted proponents of ’statist’, ’cosmopolitan’, and ’pluralistic’ perspectives against each other, each claiming to represent perspectives fulfilling normative criteria for maintaining democratic legitimacy in a wider global and transnational sphere. This paper sets out to act in defence of one of these models in particular, n
The city of Brăila, Romania, has been undergoing a lot of changes in the last two decades, but as the city is shrinking there is a new initiative to change the current paradigm and to reinvent the city. This process starts with the creation of an urban system with the neighboring city of Galați that will attract more funds from a regional and national level. The first steps have been taken in this
The study investigates the underlying factors and motives that led to the planning of collective housing in Sweden, from the 1930s until today. The brand new collective housing KomBo is used as an example to illuminate the current practice for collective housing planning. Through a critical review of various planning related documents and a total of five interviews, the study conclude the followin
In an efficient market, assets reflect all available information. Hence, investors cannot earn abnormal returns by conducting fundamental analysis since all financial data is impounded in the asset. The only way for an investor to earn higher returns is by incurring increased risk. However, a growing body of evidence appears to contradict market efficiency and common notion of risk compensation. P
The incidence of atherosclerosis is significantly increased in rheumatoid arthritis (RA). Infection is one factor that may be involved in the pathogenesis of both diseases. The cause of RA and atherosclerosis is unknown, and infection is one of the factors that may be involved in the pathogenesis of both diseases. The aims of this study were to identify bacteria in the aortic adventitia of patient
The inducement of electroactive consortia was carried Out in dual-chamber MFCS using acetate-based substrate- and a protein-rich synthetic wastewater in fed-batch mode. The characteristics of these MFCs were then compared. MFCs based on acetate-induced consortia (MFCAce) achieved more than twice higher maximum power, and one half of optimal external resistance in comparison to MFCs based on consor
